The Mizielinska lab at the UK DRI at King's is seeking to appoint an organised and enthusiastic research technician to support the research group. This position will involve significant work in protein biochemistry and requires consistency and attention to detail. The post-holder will also provide support to and carry out general organisational, technical and research duties to allow the smooth and efficient running of the research group. Dr Sarah Mizielinska’s group carries out research into nucleocytoplasmic transport dysfunction, sharing common focus on the two neurodegenerative diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). You will work on an ongoing research project in the lab investigating protein phase separation, working closely, and supervised by a postdoctoral research associate in the group. You will contribute to the productivity of this project in understanding neurobiology and neurodegenerative disease to find effective therapeutic strategies. Ref: 046345, Closing date: 30 May 2022
Apply to centreThe Barnaghi lab at the UK DRI Care Research & Technology is seeking a software engineer to join a dedicated cross-functional team building an innovative technology platform to support the care of people affected by dementia and other conditions. This is an unusual opportunity to contribute to a project that is both highly technical and positive in impact, working alongside dedicated developers, clinical researchers, data scientists, healthcare professionals and designers. You will have an influential role in the planning, implementation, and deployment of our system, which is being rolled out in growing number of care settings. We use an agile approach to software development, following best practices for version control, build automation and deployment. The role will inevitably evolve but you can expect to be working on user interface development and data integration, as well as technical infrastructure for data management (including an EHR system) and execution of machine learning models. Ref: MED03166, Closing date: 17 June 2022
Apply to centreThe UK DRI is looking for an experienced research scientist to lead our new Single Cell and Spatial Transcriptomics (SCST) Platform, providing collaboration opportunities and technical support across the distributed structure of the UK DRI. You will manage the application of techniques in single cell and spatial transcriptomics to neurodegenerative disease research, providing expert knowledge in SCST, along with technical support, to scientists across all seven UK DRI centres. Working with scientists on a range of neurodegenerative disease types, mechanisms, and models, you’ll implement the best available technology for the job at hand and strive for excellence in data quality to help meet the scientific aims of the UK DRI. Ref: 1884136, Closing date: 25 May 2022
Apply to centreThe UK DRI at Imperial have an exciting role for an experienced technician to provide technical support and management on projects related to the human neuropathology of Alzheimer’s disease in Prof Paul Matthews’ group. Candidates with prior experience with handling preclinical models or human tissues and in processing and performing analyses of their histopathology will be prioritised. Availability of a CyTOF and imaging mass cytometer will allow post holders to develop new expertise related to the multivariate analyses of cellular marker proteins with these exciting, advanced tools. Having experience in DNA and RNA preparation, PCR, qPCR and Western blotting will be an advantage. Technicians in the UK DRI at Imperial enjoy excellent career development opportunities including the opportunity to participate in the Technicians’ Network at Imperial and more widely with technologists across the UK DRI. Ref: MED03099, Closing date: 29 May 2022
Apply to centreThe UK DRI at Cambridge is seeking an experienced Centre Manager to support all aspects of the Centre’s operations, working with the UK DRI Headquarters team and Clinical Neurosciences support teams. The Centre Manager is a key strategic and operational leadership post critical to developing and enhancing the Centre’s positioning as a state-of-the-art dementia research institute. The post-holder will work with the Centre Director to ensure the effective execution and running of the UK DRI Centre and projects on a day-to-day basis to enable key milestones to be met. S/he will take lead responsibility for the financial and operational management of the Centre including its staffing, equipment, health and safety, working closely with the UK DRI at Cambridge Laboratory Manager and Administrator as well as liaising with a wide range of internal scientific and administrative staff, external bodies such as collaborating research partners, laboratories, institutions and Universities and provision of regular reports (financial and progress) to UK DRI central administration. Ref: ZE29308, Closing date: 29 May 2022
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