The role of capillary pericytes in health, stroke and Alzheimer's disease
Professor David Attwell, FRS, FMedSci, Acad Europaea is the Jodrell Professor of Physiology at University College London. Professor Attwell studied physics in Oxford, and then did a PhD in neuroscience with Julian Jack. After a post-doc in Berkeley studying the retina with Frank Werblin, he came to UCL. The Attwell lab is interested in signalling between neurons, glial cells (microglia, oligodendrocytes and astrocytes) and the vasculature, and in how the brain's energy supply is controlled and determines the computational power of the brain, using patch-clamping, 2-photon imaging, immunolabelling and mathematical modelling techniques.
In this UK DRI seminar, Professor Attwell will share exciting data from his lab that suggest a new role of amyloid beta in reducing cerebral blood flow via pericyte-mediated capillary constriction.
In addition to the live event, the seminar will be streamed online. Click here for webstream link.