​UK DRI at UCL

Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test.

• Specialisms at UCL
• Mechanistic understanding of dysfunction in cells and neural systems
• Gene expression and biological pathways in single cells related to the progression of Alzheimer’s disease
• New biomarkers to monitor disease progression
• Deficits in axonal transport in early neurodegeneration
• Wnt signalling in synapses to discover new targets for future dementia therapies

• Read more about UCL

  From lab bench to bedside, and back again 

  UCL was selected as the hub of the UK DRI in 2016 because of its strength to bring together excellent clinical and basic neuroscience research to advance our understanding of neurodegeneration and identify novel targets and therapeutic approaches for dementia. As the hub, it has a larger research programme and also is the location for the national headquarters team who connect the whole institute together.

  Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test. The groups believe in intervening earlier in disease in order to change the trajectory.

  We need to better understand the diversity and complexity of neurodegenerative diseases, like Alzheimer's disease, in order to understand the mechanisms involved, and ultimately how we can alter them to improve people's lives.

  We must find treatments quicker, and that's why the UK DRI at UCL is taking a novel approach by integrating diverse expertise for efficiency, from genetics to diagnostics.

  This work is enhanced by incredible clinical resources. Researchers have access to unique clinical cohorts, where comprehensive data has been collected throughout disease progression including memory assessments and brain tissue. The UK DRI at UCL provides a clinical arm to the whole of the UK DRI.

  The future iconic home of the UK DRI at UCL will be alongside UCL's Queen Square Institute of Neurology in a new building on Gray's Inn Road.

  Visit the UK DRI at UCL local website for up-to-date news.

Apply for latest jobs at UCL

• Centre Research Administrator, UK DRI at UCL

  Applications are open for a Centre Research Administrator to support the UK DRI at UCL, one of seven centres of the UK Dementia Research Institute. You will work closely with the Centre Manager to provide a varied, efficient and effective support function to enable cutting-edge science into the neurodegenerative disorders that cause dementia. You’ll need to have experience of research grant administration or budget management coupled with an administrative background in Higher Education; experience of working in a research-intensive laboratory environment is very desirable. You’ll have great organisation and prioritisation skills, strong communication skills and a commitment to providing a responsive and helpful support function to colleagues in the centre. This is an exciting chance for an experienced administrator to directly facilitate critical research, helping embed a streamlined administrative function into the centre. Ref: 1833472, Closing date: 3 November

  Apply to centre
• UK DRI Group Leader (Senior/Principal Fellow) in dementia and neurodegeneration at UCL

  The UK DRI at UCL are looking to appoint a new Group Leader (Senior/Principal Fellow), who will lead an internationally competitive research programme, relevant to the area of neurodegeneration, with the ultimate aim of improving human health. You will receive extensive support from the UK DRI, including up to £1.5 million start-up funding over a five-year period, appointment based on the MRC tenure-track route, access to shared equipment and technology across a national institute and membership of a community of world-leading scientists. You are also entitled to the full range of UCL staff benefits and development opportunities. You will have substantial postdoctoral experience, a proven track record of internationally competitive scientific research relevant to the UK DRI and a commitment to, appreciation and understanding of the mission of the UK DRI. You’ll be experienced in planning and developing projects or programmes of research and have a wide knowledge of techniques and methodologies related to research in neurodegeneration. You’ll propose an exciting and innovative programme of research that demonstrably interfaces and compliments the UK DRI’s current portfolio and science strategy, and evidence that you have the potential to lead, inspire and develop a research group into an excellent team. Rolling deadline.

  Apply to centre