New scientific discoveries,
new hope to stop dementia

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Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research

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Public affairs

Leading European neuroscientists call on Commission to end Horizon Europe uncertainty

The directors of four of Europe’s leading neuroscience research institutes – which together form the CURE-ND alliance (Catalysing a United Response in Europe to Neurodegeneration) – have today called upon the President of the European Commission, Ursula von der Leyen, to confirm the UK’s full association to Horizon Europe without delay.

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Research

Researchers identify way to enhance breakdown of misfolded proteins in neurodegenerative disease

A new study led by Prof David Rubinsztein (UK DRI at Cambridge) has identified a way to enhance the cell’s ability to clear away misfolded proteins, such as those implicated in neurodegenerative diseases like Alzheimer’s.

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Institute news

Brain injury and modelling microglia: third round of cross-centre postdocs announced

We are pleased to announce the latest recipients of our cross-centre postdoctoral awards – a scheme designed to stimulate exciting new academic relationships, and encourage collaboration between researchers across our seven centres.

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Race to Cures

Our new report on how discovery research will
fast-track dementia treatments

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Translation

UK DRI at King's spin-out receives £56M investment for gene therapy in Frontotemporal dementia

Co-founded by Prof Chris Shaw (UK DRI at King's), AviadoBio will use a patented gene therapy platform to develop innovative treatments for people living with neurodegenerative diseases. If successful, these treatments have the potential to permanently correct faulty genes, transforming the lives of individuals affected.

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Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Trial recruitment

Get involved in dementia research

Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.

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Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
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Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

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Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
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Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes

Founding funders

Latest tweets from @UKDRI

💡Exciting opportunity for a Senior Research Technician to join Prof Bart De Strooper's lab (UK DRI at UCL) & work o… https://t.co/9jxat1J8NY
18 Aug 2022 16:13

RT @AshwinVV: Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's Disease 🎉Delighted to share ou…
18 Aug 2022 08:41