New scientific discoveries,
new hope to stop dementia

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Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research

Vacancies
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Comment

Global dementia cases forecasted to triple by 2050

The Global Burden of Disease study examines the impact of major dementia risk factors on projections, and urges significant intervention through lifestyle changes, expanded health and social care resources and investment in research to find much-needed treatments. UK DRI Director Prof Bart De Strooper comments on the findings.

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Awards

Pioneering geneticist Prof John Hardy receives knighthood in New Year Honours 2022

Congratulations to Prof John Hardy (UK DRI Group Leader at UCL) who has been awarded a knighthood as part of the New Year Honours 2022. Prof Hardy’s groundbreaking studies on the genetics underlying Alzheimer’s has brought us closer to understanding the root causes of the disease, forming the foundations for many promising therapies currently in development.

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Race to Cures

Our new report on how discovery research will
fast-track dementia treatments

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UK DRI at King's spin-out receives £56M investment for gene therapy in Frontotemporal dementia

Co-founded by Prof Chris Shaw (UK DRI at King's), AviadoBio will use a patented gene therapy platform to develop innovative treatments for people living with neurodegenerative diseases. If successful, these treatments have the potential to permanently correct faulty genes, transforming the lives of individuals affected.

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Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Trial recruitment

Get involved in dementia research

Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.

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Alzheimers Care
Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
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Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

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Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
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Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes

Founding funders

Latest tweets from @UKDRI

RT @Daniell19244313: 👉Do you want to help people with neurodegenerative diseases live well in their own homes? 👉 Do you want to work within…
19 Jan 2022 19:21

RT @TheCrick: 📰 Researchers from @PataniLab have uncovered the diverse origins of #MND, which can converge to turn once helpful and protect…
19 Jan 2022 17:32