Vacancies

About us

The UK Dementia Research Institute (UK DRI) is the biggest UK initiative supporting research to fill the major knowledge gap in our basic understanding of the diseases that cause dementia.

Research from UK DRI at UCL covers the journey from the patient to the laboratory and back to the patient with improved diagnosis, biomarkers and candidate therapies put to the test.

The Krupic Lab at the UK DRI at UCL aims to understand how accumulation of Tau and amyloid-beta pathology affects hippocampal-entorhinal neural networks and cognitive functions in age-related neurodegenerative diseases such as Alzheimer’s disease using cutting-edge neural recording techniques, state of the art behaviour techniques, and computational approaches.

About the role

We are now recruiting a highly motivated, experienced, and self-driven Research Fellow to join the Krupic Lab to help investigate the role of disrupted deep brain circuitry in diminished spatial memory function in Alzheimer’s disease. The research will focus on both healthy and Alzheimer’s disease-related interactions modelled by accumulation of amyloid-beta and Tau proteins. One of your main tasks will be to help implement the long-term neural recordings using smart Kages.

The post is available from 15 January 2025 and is funded by the UK DRI until 31 May 2025 in the first instance, with the possibility of extension.

If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact the Institute of Neurology HR Team (ion.hradmin@ucl.ac.uk).

Informal enquiries regarding the role can be addressed to Dr Julija Krupic (j.krupic@ucl.ac.uk). 

A full job description and person specification for this role can be accessed on the UCL website. 

About the role
We have an exciting opportunity for an individual with work experience in a life science field to join our Core Informatics team. We seek someone who is excited and committed to tackling dementia through collaborative efforts across a dementia organisation that is committed to advancing dementia research.

You will participate in several stages of data life cycle management, such as processing, curating, managing, and submitting the large and diverse amounts of data generated and prioritised by research groups from across the UK DRI. The data that you will be working with will have a focus on the non-neuronal cells of the brain, known as glia, as well as exploring the interactions between the immune system and nervous system.

What we are looking for
You will have a Master’s degree in a scientific or numerate field and familiarity with bioinformatics techniques and data curation. Practical experience with processing and analysis of large datasets, particularly next-generation sequencing, is essential, as is an understanding of the UK DRI, an interest in its research work, and a commitment to supporting high-quality research. Demonstrable programming skills in R and/or Python, excellent oral and written communication skills, and good interpersonal skills are also a requirement.

Please visit the UCL website for full details and to apply. 

About the role

We are recruiting a Research Technician to provide technical support by assisting the lab members with various experimental procedures, analysis of results, and lab organisation, aiming not only to apply the current methods used in the laboratory, but also to improve their efficacy and expand their reach. You will work under the direct supervision of three Research Fellows but be expected to work independently and provide input into the design and execution of experiments on a day-to-day basis.

The post is available immediately and is funded by the Alzheimer’s Association for 18 months in the first instance.

If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact the Institute of Neurology HR Team (ion.hradmin@ucl.ac.uk).

Informal enquiries regarding the role can be addressed to Samantha Henry (s.henry@ucl.ac.uk).

About you

You’ll have a BSc (or equivalent) in a relevant discipline such as Neuroscience, Physiology, Biology, or Medicine, experience with histology and tissue staining, and protein isolation, and with imaging and image analysis. Excellent communication and interpersonal skills, the ability to act on your own initiative and prioritise your own work to deadlines, and knowledge of neuroscience-related themes are also essential for this role.

This role does not meet the eligibility requirements for a Skilled Worker Visa certificate of sponsorship under UK Visas and Immigration legislation. Therefore, UCL will not be able to sponsor individuals who require the right to work in the UK to carry out this role.

For full details and to apply, visit the UCL website.

PhD Studentship in Neuroscience

Imperial College London

Hammersmith Campus, London, UK

Applications are invited for a 3.5-year PhD studentship supported by the Edmond J. Safra Foundation to join the group of Dr Carola Radulescu in the Department of Brain Sciences for a project to study: Age-dependent mechanisms of α-Synuclein dynamics in synaptic function 

The project is based at Imperial’s Hammersmith Campus and White City Campus. The candidate will be under the supervision of Dr Carola Radulescu, Edmond J Safra Research Fellow in the Department of Brain Sciences and will benefit an active and engaged postgraduate community at Imperial.

Age-related neurodegenerative conditions are the greatest health challenge of our century. Today, over 1 million people in the UK are living with age-related neurodegenerative conditions leading to debilitating dementia and movement disorders, including Alzheimer’s, Parkinson’s, and motor neuron disease. The impact of these incurable and progressive conditions on individuals and their families is devastating. The cost to the economy and public services is large and growing as the UK population ages. However, due to major advances in our understanding of the biology of these diseases, the scientific field is at a tipping point, with the next decade promising to deliver transformative breakthroughs in therapies and a new era of predictive, preventative, and precision medicine for neurodegenerative conditions.

Applications will be considered on a rolling basis with a final closing date of 31 January 2025.

For full details, visit here.