Dr Veronique Miron

PhD (She/Her)

Group Leader

Using human brain tissue analysis and experimental modelling to understand how myelin changes with ageing and dementia

Condition

Alzheimer's disease, Mild cognitive impairment

Topics

Cell biology of neurons & glia, Ageing, Immune system, Molecular mechanisms

Techniques

Bioinformatics, Drug screening, Flow cytometry, Next generation sequencing, Single cell / nucleus transcriptomics, Spatial transcriptomics

Biography

Prof Veronique Miron’s research focuses on white matter health and pathology, revealing the cellular and molecular mechanisms by which oligodendrocytes become dysfunctional in ageing and neurodegenerative diseases such as Alzheimer’s. Her work has shown that communication between oligodendrocytes and other glial cells is critical for myelin maintenance and repair.

In addition to research, Prof Miron is an advocate for equality and diversity in STEM, and supporting the ECR community. 

Honours & awards

  • International Society for Neuroimmunology (ISNI) Mid-Career Award in Fundamental Neuroimmunology 2025
  • Elected to the Royal Society of Canada (College of New Scholars) 2024
  • Unity Health Toronto Legacy Award 2024
  • MRC Senior Non-Clinical Fellowship 2021
  • Suffrage Science Award in Life Sciences 2020
  • MRC Career Development Award 2015

News

Key publications

PLoS Biol
Published

Monocyte-secreted Wnt reduces the efficiency of central nervous system remyelination.

Authors
Bianca M Hill, Rebecca K Holloway, Lindsey H Forbes, Claire L Davies, Jonathan K Monteiro, Christina M Brown, Jamie Rose, Neva Fudge, Pamela J Plant, Ayisha Mahmood, Koroboshka Brand-Arzamendi, Sarah A Kent, Irene Molina-Gonzalez, Stefka Gyoneva, Richard M Ransohoff, Brian Wipke, Josef Priller, Raphael Schneider, Craig S Moore, Veronique E Miron
Monocyte-secreted Wnt reduces the efficiency of central nervous system remyelination.
Nat Commun
Published

Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration.

Authors
Irene Molina-Gonzalez, Rebecca K Holloway, Zoeb Jiwaji, Owen Dando, Sarah A Kent, Katie Emelianova, Amy F Lloyd, Lindsey H Forbes, Ayisha Mahmood, Thomas Skripuletz, Viktoria Gudi, James A Febery, Jeffrey A Johnson, Jill H Fowler, Tanja Kuhlmann, Anna Williams, Siddharthan Chandran, Martin Stangel, Andrew J M Howden, Giles E Hardingham, Veronique E Miron
Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration.
Nature
Published

Microglia regulate central nervous system myelin growth and integrity.

Authors
Niamh B McNamara, David A D Munro, Nadine Bestard-Cuche, Akiko Uyeda, Jeroen F J Bogie, Alana Hoffmann, Rebecca K Holloway, Irene Molina-Gonzalez, Katharine E Askew, Stephen Mitchell, William Mungall, Michael Dodds, Carsten Dittmayer, Jonathan Moss, Jamie Rose, Stefan Szymkowiak, Lukas Amann, Barry W McColl, Marco Prinz, Tara L Spires-Jones, Werner Stenzel, Karen Horsburgh, Jerome J A Hendriks, Clare Pridans, Rieko Muramatsu, Anna Williams, Josef Priller, Veronique E Miron
Microglia regulate central nervous system myelin growth and integrity.

The Miron Lab

Explore the work of the Miron Lab, using a combination of human brain tissue analysis and experimental modelling to understand how myelin changes with aging and dementia, and how we can intervene to prevent cognitive decline

Miron Lab
Astrocyte brain cells