Five years of innovation
in discovery science

The UK’s leading biomedical research institute
dedicated to neurodegenerative diseases

Watch film

Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research

Vacancies
220427 Dementia Dri Labmain 015
World Alzheimer's Month

Filling the dementia knowledge gap

This World Alzheimer’s Month, we’re taking a closer look at some of the gaps that still exist in our understanding of dementia, and how researchers at the UK DRI are filling them with vital discovery research. Follow our campaign on social media using the hashtag #FillingTheGaps.

Read more
If62 X34 Gfp Iba1 Gfap  Sb293 S1 Ipsi 00117
Research

New study discovers how neurons die in Alzheimer’s disease

A research team led by Prof Bart De Strooper (UK DRI at UCL) has finally discovered how neurons die in Alzheimer’s disease. Subject of scientific discussion for the past decades, the breakthrough research paper illustrates how neurons initiate a programmed form of cell death, known as necroptosis, when they are exposed to amyloid plaques and tau tangles.

Read more
Siddharthan Chandran Credit James Duncan Davidson
Leadership

Professor Siddharthan Chandran appointed as new Director of the UK DRI

We are delighted to announce that Professor Siddharthan Chandran, a world-leading expert in neurodegenerative diseases, will become the new Director of the UK DRI from 1 October 2023.

Read more

Keep in touch with UK DRI activities

Sign up to our monthly e-newsletter - 'Inside Eye on UK DRI'

Subscribe
Synapse 3 D Red
Update

Three new Trustees to bring unique expertise to UK DRI Board

We are pleased to announce that three new Trustees will join our Board this year. Joining the nine existing Trustees, the new Board members bring a wealth of expertise that will prove invaluable to the Institute as it enters its next phase under new Director Prof Siddharthan Chandran. The three new Trustees are Emma Whitcombe (Charity Consultant), Rabia Khan (Serna Bio) and Roudie Shafie (OVID Health).

Read more
Dementia Research Uk Landscape Screenshot
Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

Read more
180724 Grossman Nir Brain Stimulation 051
Trial recruitment

Get involved in dementia research

Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.

Read more

Discovering hope
for dementia

Find out how we are leading the
journey of discovery in dementia

Read more
Alzheimers Care
Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
Barnes Mouse Hippocampus Smaller
Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

Read our science vision
Connectome Crowd Red
Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
Themes Pin In Board Red
Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes

Founding funders