Five years of innovation
in discovery science

The UK’s leading biomedical research institute
dedicated to neurodegenerative diseases

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Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research

Vacancies
Dementia Manifesto
Policy

UK DRI and sector leaders launch Dementia Manifesto

The UK DRI has joined forces with Dementia UK, Alzheimer’s Research UK, Alzheimer’s Society and Alzheimer Scotland to urge the next UK government to take action on dementia, setting out five key areas for change.

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Funding

New UK DRI scheme launched to fund bold and boundary pushing research

We are delighted to announce the first recipients of the new ‘Key Questions’ intramural funding programme, leveraging the unique strengths and capabilities of our Institute to catalyse bold and ambitious research projects, which adopt multidisciplinary and innovative approaches.

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Grand Challenge

Uncovering the earliest signs of Alzheimer’s disease

A major new UK DRI Grand Challenge project, led by Prof Karen Duff, Centre Director of the UK DRI at UCL, seeks to understand the earliest stages of Alzheimer’s, by simultaneously examining molecular and cellular changes in mice and studying the very first behavioural changes in humans at risk of the disease.

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Update

Three new Trustees to bring unique expertise to UK DRI Board

We are pleased to announce that three new Trustees will join our Board this year. Joining the nine existing Trustees, the new Board members bring a wealth of expertise that will prove invaluable to the Institute as it enters its next phase under new Director Prof Siddharthan Chandran. The three new Trustees are Emma Whitcombe (Charity Consultant), Rabia Khan (Serna Bio) and Roudie Shafie (OVID Health).

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Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Get involved

Friends of CR&T: A new network to shape dementia research

The UK DRI exists to improve the lives of people affected by dementia. By involving people who have lived experience in our research, we can ensure new treatments and technologies meet the needs of those affected.

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Discovering hope
for dementia

Find out how we are leading the
journey of discovery in dementia

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Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
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Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

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Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
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Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes