New scientific discoveries,
new hope to stop dementia

Find out more in our new digital brochure


Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research


UK DRI report urges action to reduce health inequalities in dementia

Our new report details the impact of scientific research on health inequalities for people affected by dementia. As the report launches at the start of World Alzheimer’s Month, we are urging the Government to prioritise funding for scientific innovation, to facilitate larger dementia trials, remove barriers that stop people taking part in research and close the gap on health inequalities.

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Better Ageing Older People

How will dementia diagnosis and treatment change in the next 10 years?

As the number of people living with dementia increases, there is an ever greater need for breakthroughs in developing treatments and improving lives. So how close are we to new therapeutics? And what innovations will help us get there? This World Alzheimer's Day, we asked UK DRI researchers for their predictions on what we can expect over the next decade, and where they see the most promising advances.

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Motor Neuron Shutterstock Kateryna Kon

Research reveals new insights into disease mechanisms underlying ALS

A new study led by Prof. Giampietro Schiavo (UK DRI at UCL) has uncovered why certain types of motor neurons are differentially affected in amyotrophic lateral sclerosis (ALS). The findings, published in the journal Acta Neuropathologica Communications, could open up new avenues for drug discovery and treatments for this disease.

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Race to Cures

Our new report on how discovery research will
fast-track dementia treatments

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Gene Therapy Chris Shaw Web

UK DRI at King's spin-out receives £56M investment for gene therapy in Frontotemporal dementia

Co-founded by Prof Chris Shaw (UK DRI at King's), AviadoBio will use a patented gene therapy platform to develop innovative treatments for people living with neurodegenerative diseases. If successful, these treatments have the potential to permanently correct faulty genes, transforming the lives of individuals affected.

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Dementia Research Uk Landscape Screenshot
Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Trial recruitment

Get involved in dementia research

Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.

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Alzheimers Care
Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
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Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

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Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
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Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes

Founding funders

Latest tweets from @UKDRI

🗨️UK DRI Director Prof Bart De Strooper joins other experts in the field to unpick this week's announcement about n…
30 Sep 2022 16:05

RT @n_skene: Just a few more days to apply for this postdoc position! Want to do cutting edge experimental work in a close knit team toge…
30 Sep 2022 12:53