Five years of innovation
in discovery science

The UK’s leading biomedical research institute
dedicated to neurodegenerative diseases

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Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research

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Director of the UK Dementia Research Institute

An exciting and unique opportunity to lead the UK’s foremost biomedical research institute dedicated to neurodegenerative diseases. Applications due 13 March.

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Genetics, microglia and complement: fourth round of cross-centre postdocs announced

We are delighted to announce the latest recipients of our cross-centre postdoctoral awards – a scheme designed to stimulate exciting new academic relationships and encourage collaboration between researchers across our seven centres.

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ALS/MND research at UK DRI

Amyotrophic Lateral Sclerosis (ALS), or Motor Neurone Disease (MND), is a fatal neurodegenerative condition that causes progressive weakness of the muscles due to the degeneration of motor neurones in the brain and spinal cord. Many of our pioneering research programmes are committed to finding much-needed treatments for those people affected now and in the future.

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“I'm not going to give up”: in conversation with 2022 MRC Millennium Medal winner Prof Sarah Tabrizi

For her outstanding efforts and achievements, Prof Tabrizi is recognised with this year’s prestigious MRC Millennium Medal. We caught up with Sarah to reflect on her career to date, passion for scientific investigation and tireless drive to deliver a cure for her patients at the National Hospital for Neurology and Neurosurgery (NHNN), part of UCLH.

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Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Trial recruitment

Get involved in dementia research

Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.

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Discovering hope
for dementia

Find out how we are leading the
journey of discovery in dementia

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Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
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Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

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Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
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Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes

Founding funders

Latest tweets from @UKDRI

RT @suvankarpal: Congratulations to the formidable @drarpan100 for winning the ECR platform presentation prize at the #CUREND clinical work…
03 Feb 2023 17:11

RT @DrArpan100: Absolutely super, comprehensive talk by @DrNatalieRyan @drcionucl @UKDRI on her research into familial Alzheimer's dementia…
03 Feb 2023 12:09