Five years of innovation
in discovery science

Uncovering new knowledge to develop
urgent treatments for dementia

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Our research

See how our science is tackling dementia

Lab profiles

Our teams are growing

Come join us in transforming dementia research

Vacancies
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Events

A clinical and scientific perspective on lecanemab

On 13 December at 16:00, join us for a virtual roundtable where an expert panel of clinicians and basic researchers will discuss the promising Phase III trial data of lecanemab for the treatment of Alzheimer’s disease, following presentation of results at CTAD.

More info
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Featured

ALS/MND research at UK DRI

Amyotrophic Lateral Sclerosis (ALS), or Motor Neurone Disease (MND), is a fatal neurodegenerative condition that causes progressive weakness of the muscles due to the degeneration of motor neurones in the brain and spinal cord. Many of our pioneering research programmes are committed to finding much-needed treatments for those people affected now and in the future.

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News

Prof Bart De Strooper is to step down as Director of the UK DRI

After six years as Director of the UK DRI, Prof Bart De Strooper is stepping down to focus on his research.

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Race to Cures

Our new report on how discovery research will
fast-track dementia treatments

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Translation

UK DRI at King's spin-out receives £56M investment for gene therapy in Frontotemporal dementia

Co-founded by Prof Chris Shaw (UK DRI at King's), AviadoBio will use a patented gene therapy platform to develop innovative treatments for people living with neurodegenerative diseases. If successful, these treatments have the potential to permanently correct faulty genes, transforming the lives of individuals affected.

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Research partners

Building connections across the dementia ecosystem

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Trial recruitment

Get involved in dementia research

Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.

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Keep in touch with UK DRI activities

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Translation and innovation

Turning breakthroughs into treatments

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
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Science Vision

Our priorities as a research institute

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

Read our science vision
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Equity, Diversity and Inclusion

Collaboration and connection

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion
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Research themes

Bringing together researchers to address major scientific questions

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes

Founding funders

Latest tweets from @UKDRI

RT @sciencecampaign: We are thrilled to announce that @UKDRI have joined CaSE. They are a fantastic addition to our membership, and we look…
06 Dec 2022 17:33

We're pleased to announce that the UK DRI has joined the Campaign for Science & Engineering @sciencecampaign (CaSE)… https://t.co/NlfpasybRU
06 Dec 2022 17:32