This World Alzheimer’s Month, we’re taking a closer look at some of the gaps that still exist in our understanding of dementia, and how researchers at the UK DRI are filling them with vital discovery research. Follow our campaign on social media using the hashtag #FillingTheGaps.
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A research team led by Prof Bart De Strooper (UK DRI at UCL) has finally discovered how neurons die in Alzheimer’s disease. Subject of scientific discussion for the past decades, the breakthrough research paper illustrates how neurons initiate a programmed form of cell death, known as necroptosis, when they are exposed to amyloid plaques and tau tangles.
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We are delighted to announce that Professor Siddharthan Chandran, a world-leading expert in neurodegenerative diseases, will become the new Director of the UK DRI from 1 October 2023.
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We are pleased to announce that three new Trustees will join our Board this year. Joining the nine existing Trustees, the new Board members bring a wealth of expertise that will prove invaluable to the Institute as it enters its next phase under new Director Prof Siddharthan Chandran. The three new Trustees are Emma Whitcombe (Charity Consultant), Rabia Khan (Serna Bio) and Roudie Shafie (OVID Health).
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The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.
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Group Leader Dr Nir Grossman (UK DRI at Imperial) is leading a new trial using deep electrical currents applied to the brain of people living with Alzheimer's disease. The team are recruiting participants over the next year.
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We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.
Translation and innovation
We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.
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Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.
Equity, Diversity and Inclusion
We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.
Research themes
