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Alzheimers Research Uk Oxford 186

We are seeking programme leaders who will help transform the range and pace of research on dementias, and contribute to a vibrant, connected new institute.

The UK DRI will lead the UK’s dementia research effort and deliver a step-change in the scientific understanding of dementias. Our key goals are to generate new targets for drug development and to reinvigorate the therapeutic pipeline. 

We have awarded foundation programmes across all six UK DRI centres, which will begin in Autumn 2017 and kick-start our research. We have now opened our next wave of core recruitment to grow the institute and establish a vibrant, ambitious and interactive community centred on neuroscience, which will ultimately be made up of over 400 scientists.

As a professor or fellow at one of the six UK DRI centres, you would lead a group of postdoctoral fellows, PhD students and technical support staff. Directing activities on a local level and feeding into the organisation’s wider mission, you would provide the intellectual energy and independent thinking necessary to lead cutting-edge research, shaping the overall aims and achievements of your group.

For recruitment enquiries, please contact us on ukdri@headoffice.mrc.ac.uk or 0207 395 2226.

To be successful, you should have a proven track record of internationally competitive scientific research and persuasive plans for a new and exciting UK DRI core programme. In return, the institute offers a five-year research programme package of up to £3 million for a professor and up to £1.5 million for a fellow. Recruiting UK DRI centres are offering competitive salaries. Programme leaders will be employees of the university hosting the UK DRI centre and will be employed under the standard employment terms and conditions of that university.

The UK DRI welcomes scientists from all disciplines. We encourage you to consider the specialisms across the institute and have a discussion with the associate director of your centre of interest. You will submit one application directly to your preferred UK DRI centre, which will be strongly considered at selection stage by the institute as a whole.

This phase of recruitment is open until 26 January 2018 - please ensure you check application closing dates at each centre as they may vary. Please download our recruitment pack for role profiles and application guide.

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Our opportunities for postdoctoral researchers and technicians

Our UK DRI centres are beginning to fill positions within their foundation programmes. The institute offers interdisciplinary training and cutting-edge resources, with innovation at its heart.

From 2018 we will have many more vacancies at all levels, but please explore below to see some opportunities that are already available to join our ambitious and interactive community.

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​UK DRI at UCL

  • Specialisms at UCL
  • Mechanistic understanding of dysfunction in cells and neural systems
  • Gene expression and biological pathways in single cells related to the progression of Alzheimer’s disease
  • New biomarkers to monitor disease progression
  • Deficits in axonal transport in early neurodegeneration
  • Wnt signalling in synapses to discover new targets for future dementia therapies
  • Read more about UCL

    Research from UK DRI at UCL will cover the journey from the patient to the laboratory and back to the patient with improved diagnosis, biomarkers and candidate therapies to put to the test. Led by Professor Bart de Strooper, UK DRI Director, the team will address the key unanswered mechanistic questions that link genetic and lifecourse factors to dysfunction in molecular pathways, in cells and in neural systems during the progression of the dementias. This work will be enhanced by clinical resource to link lab work to the clinic.

    UK DRI at UCL will examine changes in gene expression and biological pathways in single cells to get a detailed picture of the changes happening during the initiation and development of Alzheimer’s disease. The UCL team will also develop new biomarkers to monitor disease progression. Programmes of work will look specifically at deficits in axonal transport as a very early step in neurodegeneration and at the role of the Wnt signaling pathway in the maintenance and function of synapses to see whether it is a promising target for future dementia therapies.

    Location: UK DRI at UCL will initially be located in a refurbished space within the Cruciform building, within UCL’s Bloomsbury campus. This location is near to Alzheimer's Research UK's UCL Drug Discovery Institute, the MRC Laboratory for Molecular Cellular Biology, the MRC Prion Unit, the Sainsbury Wellcome Centre for Neural Circuits and Behaviour, and genetic facilities. 

Apply for latest jobs at UCL

  • UK DRI Fellow at UCL

    UK DRI Fellows will lead an internationally competitive research programme with up to £1.5m in funding support, relevant to the area of neurodegeneration, with the ultimate aim of improving human health. You will draw on the knowledge and expertise of other colleagues both within and outside of the UK DRI through collaborative inputs and team working.

    Download role profile Apply to centre
  • UK DRI Professor at UCL

    UK DRI Professors will direct internationally competitive research with up to £3m programme support, relevant to the area of neurodegeneration, with the ultimate aim of improving human health. You will draw on the knowledge and expertise of other colleagues both within and outside of the UK DRI through collaborative inputs and team working.

    Download role profile Apply to centre

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