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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

JAMA neurology
Published

Serum Glial Fibrillary Acidic Protein Dynamics, Disease Progression, and Therapy Response in Multiple Sclerosis

Authors
Maximilian Einsiedler, Sofia Sandgren, Sabine Schaedelin, Kiarra Ning, Aleksandra Maleska Maceski, Johanna Oechtering, Christian Cordano, Lester Melie-Garcia, Jeffrey M Gelfand, Alessandro Cagol, Roland G Henry, Sebastian Finkener, Patrice H Lalive, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D'Souza, Lars G Hemkens, Özgür Yaldizli, Bettina Fischer-Barnicol, Tobias Derfuss, Patrick Roth, Marina Herwerth, Claudio Gobbi, David Brassat, Björn Tackenberg, Rosetta Pedotti, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Georgina Arrambide, Fredrik Piehl, Henrik Zetterberg, Bruce A C Cree, Maria Pia Sormani, Ludwig Kappos, Stephen L Hauser, Michael Khalil, Cristina Granziera, Ari J Green, David Leppert, Pascal Benkert, Ahmed Abdelhak, Jens Kuhle, Expression, Proteomics, Imaging, Clinical (EPIC) study and the Swiss MS Cohort (SMSC) investigators, Lisa Hofer, Michelle Hughes, Nafiye Genc, Amar Zadic, Juan Francisco Vilchez Gomez, Riccardo Galbusera, Edoardo Galli, Jannis Müller, Marjolaine Uginet, Veronika Kana, Catarina Raposo, Jorge Oksenberg, David Conen
Serum Glial Fibrillary Acidic Protein Dynamics, Disease Progression, and Therapy Response in Multiple Sclerosis
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Exploring longitudinal relationships among Alzheimer's disease biomarkers

Authors
Benjamin Saef, Kellen K Petersen, Katherine Volluz, Yan Li, Duygu Tosun, Marta Mila-Aloma, Leslie M Shaw, Henrik Zetterberg, Jeffrey L Dage, Carrie E Rubel, Kyle Ferber, Lei Du-Cuny, Janaky Coomaraswamy, Michael Baratta, Yulia Mordashova, Ziad S Saad, Gallen Triana-Baltzer, Nicholas J Ashton, Emily A Meyers, Erin G Rosenbaugh, J Martin Sabandal, Anthony W Bannon, William Z Potter, Alzheimer's Disease Neuroimaging Initiative (ADNI), Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer's Disease Project Team, Suzanne E Schindler
Exploring longitudinal relationships among Alzheimer's disease biomarkers
Journal of the American Heart Association
Published

Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel Disease-Outcomes at 6 Months in the LACI-2 Randomized Controlled Trial

Authors
Philip M Bath, Lisa J Woodhouse, Iris Mhlanga, John Bamford, Vera Cvoro, Fergus N Doubal, Timothy J England, Ahamad Hassan, Alan A Montgomery, John T O'Brien, Christine Roffe, Nikola Sprigg, David J Werring, Joanna M Wardlaw, LACI‐2 Trial Investigators
Isosorbide Mononitrate/Cilostazol for Lacunar Cerebral Small Vessel Disease-Outcomes at 6 Months in the LACI-2 Randomized Controlled Trial
Medical image analysis
Published

Standardized evaluation of automatic methods for perivascular spaces segmentation in MRI - MICCAI 2024 challenge results

Authors
Yilei Wu, Yichi Zhang, Zijian Dong, Fang Ji, An Sen Tan, Gifford Tan, Sizhao Tang, Huijuan Chen, Zijiao Chen, Eric Kwun Kei Ng, Jose Bernal, Hang Min, Ying Xia, Ines Vati, Liz Cooper, Xiaoyu Hu, Yuchen Pei, Yutao Ma, Victor Nozais, Ami Tsuchida, Pierre-Yves Hervé, Philippe Boutinaud, Marc Joliot, Junghwa Kang, Wooseung Kim, Dayeon Bak, Rachika E Hamadache, Valeriia Abramova, Xavier Lladó, Yuntao Zhu, Zhenyu Gong, Xin Chen, John McFadden, Pek Lan Khong, Roberto Duarte Coello, Hongwei Bran Li, Woon Puay Koh, Christopher Chen, Joanna M Wardlaw, Maria Del C Valdés Hernández, Juan Helen Zhou
Standardized evaluation of automatic methods for perivascular spaces segmentation in MRI - MICCAI 2024 challenge results
Nature communications
Published

Cerebrospinal fluid biomarkers reveal transdiagnostic synaptic dysfunction across major psychiatric disorders

Authors
Andreas Göteson, Johanna Nilsson, Elena Camporesi, Anna Luisa Klahn, Elin Hörbeck, Robert Sigström, Lina Jonsson, Timea Sparding, Erik Pålsson, Aurimantas Pelanis, Anneli Goulding, Anniella Isgren, Sophie Erhardt, Simon Cervenka, Cynthia M Bulik, Henrik Zetterberg, Kaj Blennow, Carl M Sellgren, Ann Brinkmalm, Mikael Landén
Cerebrospinal fluid biomarkers reveal transdiagnostic synaptic dysfunction across major psychiatric disorders
Brain communications
Published

Peripheral and central inflammation associated with progressive cognitive decline in dementia with Lewy bodies

Authors
Peter Swann, Maura Malpetti, Leonidas Chouliaras, Simon R White, Elijah Mak, Ajenthan Surendranathan, P Simon Jones, Li Su, George Savulich, Stacey Kigar, Anna McKeever, Tim Fryer, Young T Hong, Franklin I Aigbirhio, James B Rowe, John T O'Brien
Peripheral and central inflammation associated with progressive cognitive decline in dementia with Lewy bodies
bioRxiv : the preprint server for biology
Published

Biomarker Variability Limits Individualized Amyloid Time Estimation in Alzheimer Disease

Authors
Julie K Wisch, Ziqiao Jiao, Peter R Millar, Nicole S McKay, Aleksandra Beric, Wenjing Lin, Bryce Baker, Jennifer Stauber, Sam Preminger, Mathias Jucker, Nicolas R Barthélemy, Jasmeer Chhatwal, Natalie S Ryan, Suzanne E Schindler, Carlos Cruchaga, Tammie L S Benzinger, Celeste M Karch, Randall J Bateman, Eric McDade, Jorge Llibre-Guerra, Dominantly Inherited Alzheimer Network, Alzheimer Disease Neuroimaging Initiative, Brian A Gordon, Beau M Ances, Laura Ibanez
Biomarker Variability Limits Individualized Amyloid Time Estimation in Alzheimer Disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world

Authors
Heather M Snyder, Malavika P Tampi, Paul S Aisen, Ricardo Allegri, Liana G Apostolova, Alireza Atri, Sheena Aurora, Paulo Caramelli, Lucia Crivelli, Jeffrey Cummings, Bart de Strooper, Nick C Fox, Lea Tenenholz Grinberg, John Hardy, Bruce T Lamb, Allan Levey, Oscar Lopez, Catherine Mummery, Ricardo Nitrini, Sarah Pahlke, Ronald C Petersen, K Joanne Pike, Anton P Porsteinsson, Gil D Rabinovici, Michael Rafii, Rema Raman, Marwan N Sabbagh, Stephen P Salloway, Philip Scheltens, Jonathan M Schott, Dennis J Selkoe, Gustavo Sevlever, Reisa Sperling, Malu Gamez Tansey, Christopher van Dyck, Henrik Zetterberg, Maria C Carrillo
Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

The Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale in frontotemporal dementia and Alzheimer's disease

Authors
Jessica Jiang, Eva K Larsen, Benjamin A Levett, Lucy B Core, Sophie A Froud, Ciro Della Monica, Hana Hassanin, Giuseppe Atzori, Chris Jd Hardy, Marc A Busche, Derk-Jan Dijk, Victoria L Revell, Samuel S Harris, Sofia H Eriksson, Jason D Warren
The Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale in frontotemporal dementia and Alzheimer's disease