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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

European journal of epidemiology
Published

EPIC4ND-European Prospective Investigation into Cancer and Nutrition follow-up for neurodegenerative diseases

Authors
Christina M Lill, Jan Homann, Olena Ohlei, Karl Smith-Byrne, Vivian Viallon, Jose Maria Huerta, Fanny Artaud, Yujia Zhao, Abigail Britten, Laura Deecke, Valerija Dobricic, Olatz Mokoroa, Marcela Guevara, Dafina Petrova, Miles Trupp, Jara Sabin, Mareike Gröninger, Sandra M Colorado-Yohar, Sonia Alonso-Martin, Natalia Cabrera-Castro, Sergiu Groppa, Oliver Robinson, Johnni Hansen, Sture Eriksson, Sabina Sieri, Ana Jimenez, Tammy Y N Tong, Rudolph Kaaks, Gianluca Severi, Ruth Travis, Nick Wareham, Andréa L Benedet, Henrik Zetterberg, Andre Franke, Alexis Elbaz, Lars Bertram, Roel Vermeulen, Lefkos Middleton, Giovanna Masala, Carlotta Sacerdote, Susan Peters, Verena Katzke, Pietro Ferrari, Marc J Gunter, Elio Riboli
EPIC4ND-European Prospective Investigation into Cancer and Nutrition follow-up for neurodegenerative diseases
NPJ digital medicine
Published

Real-world deployment of remote sleep monitoring technologies reveals distinct patterns associated with cognitive decline

Authors
Nan Fletcher-Lloyd, Nathalia Céspedes Gómez, Alexander Capstick, Antigone Fogel, Marirena Bafaloukou, Mahan Heydari, Alexandra Cairns, Chloe Walsh, Jessica True, CR T Group, Behnam Shariati, Ramin Nilforooshan, Payam Barnaghi
Real-world deployment of remote sleep monitoring technologies reveals distinct patterns associated with cognitive decline
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published

EXPRESS: Cerebrovascular Reactivity Delay measured by Blood Oxygen Level Dependent Magnetic Resonance Imaging and Gas Challenges: A Systematic Review

Authors
Keelin Neamh Ridge, Joanna Wardlaw, Michael Thrippleton, Michael S Stringer
EXPRESS: Cerebrovascular Reactivity Delay measured by Blood Oxygen Level Dependent Magnetic Resonance Imaging and Gas Challenges: A Systematic Review
Journal of neurology
Published

Blood-based multimodal biomarker models for differentiating early-onset Alzheimer's disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study

Authors
Hyuk Sung Kwon, So Young Moon, Mina Hwang, Hee Jin Kim, Sun Min Lee, Na-Yeon Jung, Hyemin Jang, Jeong-Min Baek, Min-Ju Kim, Myung-Hoon Han, Henrik Zetterberg, Kaj Blennow, Liana G Apostolova, Seong-Ho Koh, Eun-Joo Kim, Longitudinal study of Early-onset dementia And Family members (LEAF) investigators
Blood-based multimodal biomarker models for differentiating early-onset Alzheimer's disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study
EMBO reports
Published

Author Correction: m<sup>6</sup>A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts

Authors
Anika Pupak, Rodríguez-Navarro Irene, Kirupa Sathasivam, Ankita Singh, Amelie Essmann, Daniel Del Toro, Silvia Ginés, Ricardo Mouro Pinto, Gillian P Bates, Ulf Andersson Vang Ørom, Eulàlia Martí, Verónica Brito
Author Correction: m<sup>6</sup>A modification of mutant huntingtin RNA promotes the biogenesis of pathogenic huntingtin transcripts
Alzheimer's research & therapy
Published

Blood-based immunophenotyping of T cell profiles in patients with neurodegenerative disorders

Authors
Frederika Malichova, Peter Swann, Stacey L Kigar, Natalia Savinykh Yarkoni, Julia Goddard, Kei Onn Lai, Leonidas Chouliaras, Ajenthan Surendranathan, Lorinda Turner, George Savulich, Richard Bevan-Jones, Nicholas J Ashton, Kaj Blennow, Henrik Zetterberg, Edward Needham, Joanne Jones, William A McEwan, James B Rowe, John T O'Brien, Maura Malpetti
Blood-based immunophenotyping of T cell profiles in patients with neurodegenerative disorders
Stroke
Published

Brain Perivascular Space Morphometry Reflects Shared Familial Microvascular Architecture and Neuropsychiatric Influences

Authors
Alexandra Morozova, Maria Del C Valdés Hernández, Roberto Duarte Coello, Heather Whalley, Andrew McIntosh, Anca-Larisa Sandu Giuraniuc, Gordon D Waiter, Christopher J McNeil, J Douglas Steele, Jennifer A Macfarlane, Alison Murray, Joanna M Wardlaw
Brain Perivascular Space Morphometry Reflects Shared Familial Microvascular Architecture and Neuropsychiatric Influences
Science advances
Published

Varicose projection astrocytes: Conserved reactive cells in brain pathology

Authors
Caterina Ciani, Giulio Pistorio, Simona Giancola, Marika Mearelli, Francesca Emma Mongelli, Delaram Forouzeh, Luana Campos Soares, Marta Gonzalez Martin, Mandi E Lichtenstein, Luca Mio, Elena Christou, Kyle Hastings, Anh Quynh Nguyen Do, Paula Ramos-Gonzalez, Carlos Matute, Ugne Kuliesiute, Sari Elena Dötterer, Gediminas Luksys, Saulius Rocka, Urte Neniskyte, Daniel C Anthony, Marya Ayub, Cinzia Centelleghe, Maria Angeles Arevalo, Jean-Marie Graïc, Francesco Petrelli, Alexei Verkhratsky, Nunzio Iraci, Fabio Cavaliere, Carmen Muñoz-Ballester, Mootaz M Salman, Francesco P Ulloa Severino, Carmen Falcone
Varicose projection astrocytes: Conserved reactive cells in brain pathology
Stroke
Published

Aberrant Hippocampal Neurogenesis Is a Conserved Response to Stroke in Mice: A Multicenter Multimodel Study

Authors
Francisco J De Castro-Millán, Sandra Vázquez-Reyes, Carolina Peña-Martínez, Adrián Rodríguez-Llave, Carlos Parra-Pérez, Carmen Nieto-Vaquero, Gaia Brezzo, Kristy A Zera, Dana Straus, Jennifer E Goertz, Sanna H Loppi, Rachel R Crumpacker, Jennifer B Frye, Danielle A Becktel, Claudia Dames, Daniel Berchtold, Jill H Fowler, Andreas Meisel, Josef Anrather, Kristian P Doyle, Stuart M Allan, Marion S Buckwalter, Barry W McColl, Alicia García-Culebras, María Isabel Cuartero, María Ángeles Moro
Aberrant Hippocampal Neurogenesis Is a Conserved Response to Stroke in Mice: A Multicenter Multimodel Study
Diagnostics (Basel, Switzerland)
Published

Analytical Performance and Evaluation in Clinical Cohorts of a Fully Automated Immunoassay for Plasma Glial Fibrillary Acidic Protein

Authors
Ben Schlichtmann, Burak Arslan, Kara Johnson, Jason Patzlaff, Dusten Unruh, Miklos Szabo, Mark Holland, Jeff Todtleben, Mike Salvati, Kubra Tan, Ulf Andreasson, Jeremiah Hinson, Scott Levin, Henrik Zetterberg, Andrea Lessa Benedet, Holly Ann Hill
Analytical Performance and Evaluation in Clinical Cohorts of a Fully Automated Immunoassay for Plasma Glial Fibrillary Acidic Protein
Stroke
Published

Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI

Authors
Yu-Yuan Xu, Francesca M Chappell, Maria Valdes Hernandez, Carmen Arteaga Reyes, Una Clancy, Daniela Jaime Garcia, Stephen Makin, Michael Stringer, Michael Thrippleton, Stewart Wiseman, Yajun Cheng, Dillys Xiaodi Liu, Rosalind Brown, Fergus Doubal, Ian J Deary, Simon Cox, Danielle Kerkhofs, Julie Staals, Walter Backes, Robert van Oostenbrugge, Anna Kopczak, Marco Duering, Joanna Wardlaw
Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI
International journal of stroke : official journal of the International Stroke Society
Published

The Vascular Contribution to Dementia. World Stroke Organisation Scientific Statement

Authors
Geert Jan Biessels, Stephanie Debette, Fanny M Elahi, Fatemeh Geranmayeh, Gurpreet Hansra, Timothy M Hughes, Masafumi Ihara, Jeremy Isaacs, Hanna Jokinen, Alexi Nott, Sarah Pendlebury, Ruth Peters, Julie Schneider, Colin Smith, Eric Edward Smith, Prashanthi Vemuri, Joanna Wardlaw, Alastair Webb, Donna M Wilcock, Atticus H Hainsworth
The Vascular Contribution to Dementia. World Stroke Organisation Scientific Statement
Nature aging
Published

Spatiotemporal dynamics of tau extent and load increase in Alzheimer's disease across four longitudinal cohorts

Authors
Arthur C Macedo, Lydia Trudel, Joseph Therriault, Nesrine Rahmouni, Étienne Aumont, Gleb Bezgin, Seyyed Ali Hosseini, Cécile Tissot, Tevy Chan, Stijn Servaes, Brandon Hall, Yi-Ting Wang, Kely Quispialaya-Socualaya, Marcel S Woo, Jaime Fernandez-Arias, Jenna Stevenson, Yansheng Zheng, Marina Pereira Gonçalves, Firoza Z Lussier, João Pedro Ferrari-Souza, Pamela C L Ferreira, Bruna Bellaver, Guilherme Povala, Livia Silva do Amaral, Gassan Massarweh, Jean-Paul Soucy, Karin L Meeker, Meredith N Braskie, Tobey J Betthauser, Bradley T Christian, Ramiro Eduardo Rea Reyes, Jessica K Caldwell, Nicholas J Ashton, Thomas K Karikari, Henrik Zetterberg, Kaj Blennow, Eduardo R Zimmer, Andréa L Benedet, Sterling C Johnson, Tharick A Pascoal, Pedro Rosa-Neto, Alzheimer’s Disease Neuroimaging Initiative
Spatiotemporal dynamics of tau extent and load increase in Alzheimer's disease across four longitudinal cohorts