Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

man sitting on bed at night
- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Early microglial and astrocyte reactivity in preclinical Alzheimer's disease

Authors
Marta Fernández-Matarrubia, Andrea Valera-Barrero, Mónica Renuncio-García, Marcos Aguilella, Carmen Lage, Sara López-García, J Gonzalo Ocejo-Vinyals, Francisco Martínez-Dubarbie, Guglielmo Di Molfetta, Ana Pozueta-Cantudo, María García-Martínez, Andrea Corrales-Pardo, María Bravo, Marcos López-Hoyos, Juan Irure-Ventura, Kaj Blennow, Nicholas J Ashton, Henrik Zetterberg, Pascual Sánchez-Juan, Eloy Rodríguez-Rodríguez
Early microglial and astrocyte reactivity in preclinical Alzheimer's disease
Alzheimer's & dementia (Amsterdam, Netherlands)
Published

Apathy and affective symptoms associated with elevated plasma neurofilament light but not p-tau181 in Alzheimer's disease

Authors
Matthew J Y Kang, Dhamidhu Eratne, Samantha M Loi, Christa Dang, Alexander F Santillo, Henrik Zetterberg, Kaj Blennow, Philip B Mitchell, Malcolm Hopwood, Charles B Malpas, Dennis Velakoulis
Apathy and affective symptoms associated with elevated plasma neurofilament light but not p-tau181 in Alzheimer's disease
Biomedicines
Published

Prospective Neuropsychological and Plasma Biomarker Changes in Treatment-Naïve People Living with HIV After Antiretroviral Treatment Initiation

Authors
Charalampos D Moschopoulos, Evangelia Stanitsa, Konstantinos Protopapas, Akrivi Vatsi, Irene Galani, Henrik Zetterberg, Ion Beratis, Paraskevi C Fragkou, Sotirios Tsiodras, Dimitra Kavatha, Antonios Papadopoulos, Sokratis G Papageorgiou, Anastasia Antoniadou
Prospective Neuropsychological and Plasma Biomarker Changes in Treatment-Naïve People Living with HIV After Antiretroviral Treatment Initiation
Alzheimer's research & therapy
Published

Alcohol consumption and cerebrospinal fluid biomarkers for preclinical alzheimer's disease in a population-based sample of 70-year-olds

Authors
Silke Kern, Tobias Skillbäck, Henrik Zetterberg, Anna Dittrich, Felicia Ahlner, Anna Zettergren, Margda Waern, Nazib M Seidu, Ulf Andreasson, Kaj Blennow, Ingmar Skoog
Alcohol consumption and cerebrospinal fluid biomarkers for preclinical alzheimer's disease in a population-based sample of 70-year-olds
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

Authors
Niti Sharma, Danyeong Kim, Himadri Sharma, Moon Il Kim, Hyon Lee, Minju Kim, Nayoung Ryoo, Min Ju Kang, Jung-Min Pyun, Young Ho Park, Jisun Ryu, Hyun Jung Oh, Hyun-Sik Yang, Hang-Rai Kim, Geon Ha Kim, Sangwon Han, YoungSoon Yang, Young Chul Youn, Charlotte Teunissen, Henrik Zetterberg, Philip Scheltens, Seong Soo A An, Young-Bum Kim, SangYun Kim, Alzheimer's Disease All Markers (ADAM) Research Group
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review
Resuscitation plus
Published

Neurofilament, but not Alzheimer disease biomarkers in the acute phase correlate with cognitive performance after cardiac arrest

Authors
Johannes Lorentzson, Gisela Lilja, Erik Blennow Nordström, Kaj Blennow, Henrik Zetterberg, Christian Hassager, Matt P Wise, Andrea L Benedet, Tommaso Pellis, Hans Friberg, Nicholas Ashton, Marion Moseby Knappe
Neurofilament, but not Alzheimer disease biomarkers in the acute phase correlate with cognitive performance after cardiac arrest
Brain communications
Published

Pupil-linked arousal, cortical activity, and cognition in Alzheimer's disease

Authors
Michael C B David, Emma-Jane Mallas, Lucia M Li, Magdalena A Kolanko, Ramin Nilforooshan, Man Lai Tsoi, Hanim Karakoc, Karen Hoang, Johanna Brandt, Charikleia Triantafyllou, Dragos C Gruia, Darije Custovic, Peter J Lally, Karl A Zimmerman, Care Research and Technology Group of the UK Dementia Research Institute, Paresh A Malhotra, Gregory Scott, David J Sharp
Pupil-linked arousal, cortical activity, and cognition in Alzheimer's disease
Nature communications
Published

Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI

Authors
Anna E Fürtjes, Isabelle F Foote, Charley Xia, Gail Davies, Joanna Moodie, Adele Taylor, David C Liewald, Paul Redmond, Janie Corley, Andrew M McIntosh, Heather C Whalley, Susana Muñoz Maniega, Maria Valdés Hernández, Ellen Backhouse, Karen Ferguson, Mark E Bastin, Joanna Wardlaw, Javier de la Fuente, Andrew D Grotzinger, Michelle Luciano, W David Hill, Ian J Deary, Elliot M Tucker-Drob, Simon R Cox
Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI
The Lancet regional health. Southeast Asia
Published

Identification of protein targets for dyslipidaemia and cardiovascular diseases among people with South Asian ancestry: a mendelian randomisation study

Authors
Siwei Wu, Devendra Meena, Alexander Smith, Jingxian Huang, Georg W Otto, Yi-Hsuan Ko, James Yarmolinsky, Dipender Gill, Anand Rohatgi, Abbas Dehghan, Ioanna Tzoulaki
Identification of protein targets for dyslipidaemia and cardiovascular diseases among people with South Asian ancestry: a mendelian randomisation study
The lancet. Healthy longevity
Published

Associations between life course exposure to ambient air pollution with cognition and later-life brain structure: a population-based study of the 1946 British Birth Cohort

Authors
Thomas Canning, Jorge Arias-de la Torre, Helen L Fisher, John Gulliver, Anna L Hansell, Rebecca Hardy, Stephani L Hatch, Ian S Mudway, Amy Ronaldson, Molly Cartlidge, Sarah-Naomi James, Sarah E Keuss, Jonathan M Schott, Marcus Richards, Ioannis Bakolis
Associations between life course exposure to ambient air pollution with cognition and later-life brain structure: a population-based study of the 1946 British Birth Cohort