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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Brain communications
Published
The antagonistic pleiotropy of tau phosphorylation: plasma tau species in newborns and Alzheimer's disease
Authors
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, Cristiano Santos, Burak Arslan, Julia K Gundersen, Hlin Kvartsberg, Karin Sävman, Michael Turton, Peter Harrison, Helena Sophia Coley Gleerup, Kristian Steen Frederiksen, Steen Gregers Hasselbalch, Anja Hviid Simonsen, Tormod Fladby, Helena Barreto Henriksson, Sofia Frandberg, Ann Hellström, Floris Groenendaal, Michel N Nafash, Ella N Klaus, Xuemei Zeng, Thomas K Karikari, Henrik Zetterberg, Ulrika Sjöbom
The antagonistic pleiotropy of tau phosphorylation: plasma tau species in newborns and Alzheimer's disease
Neurology
Published
Plasma P-Tau217 as a Prognostic, Monitoring, and Risk-Stratification Biomarker of Clinical Progression in Lewy Body Disease
Authors
Sara A Lorkiewicz, Carla Abdelnour, MacKenzie L Bolen, Alena M Smith, Marian Shahid-Besanti, Dimuthu Hemachandra, Eva M Müller-Oehring, Noah Siddiqui, Laia Montoliu-Gaya, Burak Arslan, Nicholas J Ashton, Edward N Wilson, Lu Tian, Katrin Andreasson, Elizabeth Mormino, Victor W Henderson, Henrik Zetterberg, Kathleen L Poston
Plasma P-Tau217 as a Prognostic, Monitoring, and Risk-Stratification Biomarker of Clinical Progression in Lewy Body Disease
Neuron
Published
An astrocyte-microglia MFG-E8 axis promotes synapse engulfment in early amyloid pathology
Authors
Dimitra Sokolova, Francesca Puletti, Shari Addington Ghansah, Tatiana Georgiades, Yongjing Zheng, Ling Wu, Sebastiaan De Schepper, Jenny Lange, Laís S S Ferreira, Annerieke Sierksma, Julie Rebejac, Gerard Crowley, Javier Rueda-Carrasco, Bethany Geary, Raja Nirujogi, Angeliki Koutsiouroumpa, Philip Muckett, Josef Kittler, Matthew Gentry, Mathieu Bourdenx, Oliver J Freeman, Jemima J Burden, Baljit S Khakh, Soyon Hong
An astrocyte-microglia MFG-E8 axis promotes synapse engulfment in early amyloid pathology
Nature communications
Published
Two functionally distinct amyloid-β intermediates link aggregation pathways to pathology in Alzheimer's disease
Authors
Agnieszka Urbanek, Alexander J Dear, David P Rhodes, Emma F Garland, Hollie E Wareing, Harry J Baker, Willem Molenkamp, Ruixin Zhang, Gefei Chen, Axel Abelein, Simon M Bell, Juan A Varela, Thomas C T Michaels, J Robin Highley, Georg Meisl, Jan Johansson, Suman De
Two functionally distinct amyloid-β intermediates link aggregation pathways to pathology in Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Developing the World-Wide FINGERS biorepository for dementia risk reduction trials
Authors
Anna Matton, Chinedu Udeh-Momoh, Makrina Daniilidou, Erika Bereczki, Vilma Alanko, Paola Padilla, Laura D Baker, Kitti Ban, Miguel G Borda, Paulo Caramelli, Pablo Martinez-Lage Alvarez, Marta Del Campo, Carlo Ferrarese, Tobias Hartmann, Hamidul Huque, Thomas K Karikari, Derya Kaya, Rejko Kruger, Yi-Chun Kuan, Mitchell K P Lai, Karen Mather, Emily Meyers, Njideka Okubadejo, Stanley Onyango, Norfadilah Rajab, Maria Vania Rocha da Silva Nunes, Anna Rosenberg, Gessica Sala, Rosa Maria Salinas Contreras, Shahin Sayed, Margaret Scales, Seong Hye Choi, Hamid Sohrabi, Hilkka Soininen, Taiki Sugimoto, Ezequiel Surace, Yongxiang Wang, Henrik Zetterberg, Marissa Zwan, Ari Solomon, Francesca Mangialasche, Miia Kivipelto, World‐Wide FINGERS network
Developing the World-Wide FINGERS biorepository for dementia risk reduction trials
Acta anaesthesiologica Scandinavica
Published
Biomarkers in Patients With Acute Ischaemic Stroke Undergoing Thrombectomy Compared With Controls: A Pilot Study
Authors
Richard Vithal, Andreas Krönlein, Ali El-Merhi, Amar Chandan, Hilda Green, Patrik Martner, Christina Biörserud, Helena Odenstedt Herges, Henrik Zetterberg, Alexandros Rentzos, Katarina Jood, Magnus Pettersson, Jaquette Liljencrantz, Linda Block
Biomarkers in Patients With Acute Ischaemic Stroke Undergoing Thrombectomy Compared With Controls: A Pilot Study
NPJ dementia
Published
Integrated manufacturing platform for cortical organoids reveals early phosphatase and prefoldin dysregulation in <em>MAPT</em> V337M neurons
Authors
Taylor Bertucci, Kathryn R Bowles, Steven Lotz, Shiraz Bheda, Le Qi, Farhad Farjood, Katherine Whitton, Susan K Goderie, Susan Borden, Amelia Rossi, Catherine Hamann, Kate Tubbesing, Jared Rogalski, Dylan Murphy, Chiara Pedicone, Laura Maria Oja, Keith Lane, Ryan Lotz, Hailey Lotz, Jack Huber, Rebecca Chowdhury, Shona Joy, Michael Miller, David C Butler, Brigitte L Arduini, Thomas R Kiehl, Heide F B Murray, Carl Alexander Sandhof, M Catarina Silva, Stephen J Haggarty, Leander Dony, Fabian J Theis, Barbara Treutlein, Celeste M Karch, Daniel H Geschwind, Alison M Goate, Jeffrey Stern, Sally Temple
Integrated manufacturing platform for cortical organoids reveals early phosphatase and prefoldin dysregulation in <em>MAPT</em> V337M neurons
Science (New York, N.Y.)
Published
Obesity pharmacotherapies and cognition
Authors
Stina Börchers, Giulia Mazzini, Henrik Zetterberg, Christoffer Clemmensen
Obesity pharmacotherapies and cognition
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Locus coeruleus microstructural integrity and sleep disruption in the context of Alzheimer's disease pathology
Authors
Maxime Van Egroo, Yuliya Patsyuk, Marion Baillet, Nicholas M Vogt, Andrew S P Lim, Nicholas J Ashton, Shorena Janelidze, Kaj Blennow, Oskar Hansson, Henrik Zetterberg, Heidi I L Jacobs
Locus coeruleus microstructural integrity and sleep disruption in the context of Alzheimer's disease pathology
Journal of neurology
Published
Leveraging immunoprecipitation mass spectrometry and neuropathology to identify the clinical value of different blood tau species in Alzheimer's disease
Authors
Jacob Labonte, Annalise E Miner, Jenna R Groh, Laia Montoliu-Gaya, Yorghos Tripodis, Hugo J Aparicio, Katherine W Turk, Andrew E Budson, Lindsay Farrer, Lee E Goldstein, Wei Qiao Qiu, Jesse Mez, Ann C McKee, Henrik Zetterberg, Thor D Stein, Johan Gobom, Nicholas J Ashton, Michael L Alosco
Leveraging immunoprecipitation mass spectrometry and neuropathology to identify the clinical value of different blood tau species in Alzheimer's disease
Journal of Alzheimer's disease : JAD
Published
Artificial intelligence applications in microbiota-gut-brain axis research: Implications for Alzheimer's disease
Authors
Simone Lista, Enzo Emanuele, Miroslava Cuperlovic-Culf, Adam Mahdi, Vikas Singh, Susana López-Ortiz, Kayvan Khoramipour, María Merino-País, Piercarlo Minoretti, Giusy Ylenia Cisale, Amanda Heslegrave, Camillo Imbimbo, Giulia Maria Sancesario, Barbara B Bendlin, Bruno P Imbimbo, Henrik Zetterberg, Alejandro Santos-Lozano
Artificial intelligence applications in microbiota-gut-brain axis research: Implications for Alzheimer's disease
Annals of clinical and translational neurology
Published
The Association of Amyloid-β and Tau With Synaptic Dysfunction in Alzheimer's Disease
Authors
Fausto Roveta, Augusto J Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J Ashton, Federica Ribaldi, Giovanni B Frisoni, Alzheimer's Disease Neuroimaging Initiative
The Association of Amyloid-β and Tau With Synaptic Dysfunction in Alzheimer's Disease