Contact

Island Research Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0AH

Jack Novak

jack.novak@ukdri.ac.uk

Located in the heart of the Cambridge Biomedical Campus – the largest of its kind in Europe – the UK DRI at Cambridge is committed to improving the outlook for people affected by neurodegenerative conditions. The multi-disciplinary team of researchers have complementary and overlapping expertise in chemistry, biophysics, cell biology, transcriptomics and translational neuroscience.

The Centre is focused on improving understanding of the underlying mechanisms within cells that lead to neurodegeneration, and the impact of protein aggregation on the progression of neurodegenerative diseases. Through this, the team aim to deliver new mechanistic insights, new therapeutic targets and new biomarkers.

Latest news

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International Day of Women and Girls in science title image

Feb 10, 2025 - Feature

International Day of Women and Girls in Science: The inspiring scientists shaping the future of dementia research

To mark International Day of Women and Girls in Science, the UK DRI has teamed...

Learn more International Day of Women and Girls in Science: The inspiring scientists shaping the future of dementia research

Prof Victoria Chapman and Dr Maura Malpetti

Dec 10, 2024 - Event

UK DRI researchers awarded prizes at inaugural Women in Neuroscience UK Awards

The inaugural Women in Neuroscience (WiNUK) Awards brought together over 100 attendees, viewing live online...

Learn more UK DRI researchers awarded prizes at inaugural Women in Neuroscience UK Awards

Dec 06, 2024 - Feature

Celebrating public engagement in dementia research: UK DRI Engagement Prize 2024

Read about the four exceptional initiatives nominated for this years UK DRI Engagement Prize.

Learn more Celebrating public engagement in dementia research: UK DRI Engagement Prize 2024

People

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Prof Edward Avezov

Group Leader

UK DRI at Cambridge

Investigating the roles of the endoplasmic reticulum in helping maintain neuronal health, and its role in disease

Learn more Prof Edward Avezov

Prof Gabriel Balmus

Group Leader

UK DRI at Cambridge

Identifying genetic and environmental factors involved in DNA damage, neurodegeneration and ageing in neurons

Learn more Prof Gabriel Balmus

Prof Sir David Klenerman

Group Leader

UK DRI at Cambridge

Determining how protein clumps form, damage the brain and change as the different neurodegenerative diseases develop to know which ones to target for therapies

Learn more Prof Sir David Klenerman

Prof Will McEwan

Group Leader

UK DRI at Cambridge

Deciphering the mechanisms of tau accumulation and exploring new methods for treatment of tauopathies

Learn more Prof Will McEwan

Prof David Rubinsztein

Group Leader

UK DRI at Cambridge

Deciphering the link between neurodegeneration and autophagy

Learn more Prof David Rubinsztein

Prof Mina Ryten

Centre Director

UK DRI at Cambridge

Leveraging brain transcriptomics to understand the pathophysiology of Lewy body diseases

Learn more Prof Mina Ryten

Scientific focus

Read about the scientific focus of the UK DRI at Cambridge

Research at the UK DRI at Cambridge