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Research topic

Areas of interest for the UK DRI

The research topics encompass the breadth of dementia science taking place at the UK DRI, from molecular mechanisms to care research. We focus on understanding the initial stages of neurodegeneration, developing biomarkers for early detection, and innovating new therapeutic approaches. 

Our multidisciplinary approach integrates genetics, cell biology, bioinformatics, and clinical research to build a comprehensive understanding of dementia and pave the way for transformative treatments.

Research areas

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Ageing

Deciphering the biggest risk factor for dementia and neurodegenerative disease

Learn more Ageing

Cell biology of neurons & glia

Understanding the cellular mechanisms and processes contributing to health and neurodegeneration

Learn more Cell biology of neurons & glia

Genetics

Unravelling the DNA code to better understand risk factors and drivers of disease

Learn more Genetics

Immune system

Exploring how the body's defense system impacts neurodegeneration

Learn more Immune system
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Lifestyle & environment

Understanding how our environment and daily choices can influence healthy brain ageing

Learn more Lifestyle & environment
An enzyme wrapped around genetic code

Molecular mechanisms

Revealing the intricate processes maintaining health and driving neurodegeneration

Learn more Molecular mechanisms
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Sleep & Circadian rhythms

Investigating how daily biological cycles affect brain health

Learn more Sleep & Circadian rhythms
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Synapse & Circuitry

Preserving the vital communication highways between brain cells

Learn more Synapse & Circuitry
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Vascular system

Investigating vascular contributions to neurodegeneration

Learn more Vascular system

Deliverables

Biomarkers & diagnostics

Advancing early detection and precision diagnosis of neurodegenerative disease

Learn more Biomarkers & diagnostics
Minder Healthy Home

Care & Home technology

Developing innovations to support independent living and care

Learn more Care & Home technology