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Leadership

Directors and Research Operations Division Leadership

Siddharthan Chandran

Director & CEO, UK DRI

Prof Siddharthan Chandran, an internationally leading expert in neurodegenerative disease, joined the UK Dementia Research Institute as Director and CEO in October 2023. Siddharthan is a practising neurologist and scientist working at the forefront of the emerging discipline of Regenerative Neurology, renowned for his work in motor neuron disease (MND) and MS that combines laboratory and clinical research with a particular focus on human / patient stem cells for his discovery science research. Alongside his UK DRI research, Prof Chandran is Director of the Euan MacDonald Centre for Motor Neuron Disease Research and the Anne Rowling Regenerative Neurology Clinic at the University of Edinburgh. He is also a Fellow of the Royal Society of Edinburgh and the Academy of Medical Sciences.

He leads the Institute with support from the UK DRI's Board of Trustees, Scientific Directors and Operational Leadership Team.
 

Prof Siddharthan chandran stands on a stage at a conference.

I am delighted to have the opportunity to lead the UK DRI whose ultimate aim is to transform the outlook for people at risk of or living with dementia and related neurodegenerative conditions. The UK DRI is the science discovery engine that underpins the entire UK dementia ecosystem. My vision is to grow the institute into a world-leading beacon for innovation, discovery and translation for dementia.

Director & CEO

Science Executive

Prof David Attwell

Centre Director

Investigating how the brain’s energy supply is reduced by a decrease of blood flow in both Alzheimer’s disease and vascular dementia

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Karen Duff

Prof Karen Duff

Centre Director

Revealing the molecular causes and consequences of tauopathy in Alzheimer's disease and frontotemporal dementia

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Valentina Escott-Price

Prof Valentina Escott-Price

Group Leader & Research Division Lead

Using Big Data, machine learning and AI to accelerate discoveries into dementia

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Giles Hardingham

Prof Giles Hardingham

Centre Director & Directors' Counsel

Studying astrocytes to better understand their role in helping maintain a healthy brain

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Prof Baljit S. Khakh

Incoming Centre Director & Research Division Lead

Unlocking understanding of astrocyte biology and neuronal interactions

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Paul Morgan

Prof Paul Morgan

Interim Centre Director

Investigating exactly how key immune proteins contribute to Alzheimer's disease development

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David Rubinsztein

Prof David Rubinsztein

Group Leader & Research Division Lead

Deciphering the link between neurodegeneration and autophagy

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Mina Ryten

Prof Mina Ryten

Centre Director & Research Division Lead

Leveraging brain transcriptomics to understand the pathophysiology of Lewy body diseases

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Giampietro Schiavo

Prof Giampietro Schiavo

Group Leader & Research Division Lead

Restoring axonal transport deficits as a therapeutic strategy for neurodegenerative diseases

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David Sharp

Prof David Sharp

Centre Director & Research Division Lead

Using radical new approaches to assess the effects of dementia and improve the lives of people living with the condition

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Tara Spires-Jones

Prof Tara Spires-Jones

Group Leader & Research Division Lead

Deciphering why synapses and neurons degenerate and whether boosting resilience of synapses can protect the brain

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Prof Jernej Ule

Centre Director & Research Division Lead

Deciphering the role of RNA in amyotrophic lateral sclerosis and frontotemporal dementia

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Prof William Wisden

Centre Director & Research Division Lead

Investigating how and if good sleep protects against the development of dementia

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Senior Leadership Team

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Dr Jo Latimer

Chief Scientific Officer

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Lucy Wilson

Chief Communications Officer

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