Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Science (New York, N.Y.)
Published

Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration

Authors
Katie E Copley, Jocelyn C Mauna, Helen L Danielson, Qizan Chen, Busra Ozguney, Marilyn Ngo, Longxin Xie, Ashleigh Smirnov, Matt Davis, Leland Mayne, Miriam Linsenmeier, Jack D Rubien, Cristian A Bergmann, Bede Portz, Bo Lim Lee, Hana M Odeh, Longsheng Lai, Yi-Wei Chang, Martina Hallegger, Jernej Ule, Piera Pasinelli, Yan Poon, Jeetain Mittal, Nicolas L Fawzi, Ben E Black, Christopher J Donnelly, Brigid K Jensen, James Shorter
Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
Nature communications
Published

Alzheimer's Disease blood biomarkers measured through remote capillary sampling correlate with cognition in older adults

Authors
Anne Corbett, Millie Sander-Long, Nicholas J Ashton, Hanna Huber, Jakub Vavra, Luisa Sophie Braun-Wohlfahrt, Henrik Zetterberg, Laia Montoliu-Gaya, Jeffrey Cummings, Freya Bateman, Christine Davis, Clive Ballard
Alzheimer's Disease blood biomarkers measured through remote capillary sampling correlate with cognition in older adults
Alzheimer's & dementia (Amsterdam, Netherlands)
Published

Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS

Authors
Dustin B Hammers, Angelina Polsinelli, Ani Eloyan, Alexander Taurone, Maryanne Thangarajah, Tatiana Foroud, Sujuan Gao, Laurel Beckett, Renaud La Joie, Alexandra Touroutoglou, Prashanthi Vemuri, Henrik Zetterberg, Kaj Blennow, Sára Nemes, Ralitsa Kostadinova, Paul Aisen, Kelly N Nudelman, Kala Kirby, Alireza Atri, David Clark, Gregory S Day, Ranjan Duara, Neill R Graff-Radford, Ian Grant, Lawrence S Honig, Erik C B Johnson, David T Jones, Joseph C Masdeu, Mario F Mendez, Leila Parand, Kyle Womack, Erik Musiek, Chiadi U Onyike, Meghan Riddle, Emily Rogalski, Stephen Salloway, Sharon J Sha, Raymond Scott Turner, Thomas S Wingo, David A Wolk, Maria C Carrillo, Gil D Rabinovici, Bradford C Dickerson, Jeffrey L Dage, Liana G Apostolova, LEADS Consortium
Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS
Age and ageing
Published

Factors influencing implementation of an Alzheimer's disease blood test among UK old age psychiatrists: mixed-methods study using the theoretical domains framework

Authors
Hazan Jemma, Mitchell Mealing, Fabiana Lorencatto, Penny Rapaport, Ashvini Keshavan, Jonathan M Schott, Joanne Rodda, Robert Howard
Factors influencing implementation of an Alzheimer's disease blood test among UK old age psychiatrists: mixed-methods study using the theoretical domains framework
Circulation
Published

Implications of Cranial Arterial Stenosis and Dolichoectasia for Cerebral Small-Vessel Disease Etiopathogenesis: Findings From a Prospective Mild Stroke Cohort

Authors
Fei Han, Una Clancy, Carmen Arteaga-Reyes, Michael J Thrippleton, Maria Del C Valdés Hernández, Daniela Jaime Garcia, Michael S Stringer, Ellen Backhouse, Francesca M Chappell, Yajun Cheng, Dillys Xiaodi Liu, Junfang Zhang, Angela C C Jochems, Eleni Sakka, Charlotte Jardine, Gayle Barclay, Donna McIntyre, Iona Hamilton, Rosalind Brown, Yi-Cheng Zhu, Fergus N Doubal, Joanna M Wardlaw
Implications of Cranial Arterial Stenosis and Dolichoectasia for Cerebral Small-Vessel Disease Etiopathogenesis: Findings From a Prospective Mild Stroke Cohort
Nature reviews. Neurology
Published

Author Correction: UK Biobank at 20 - a growing, global resource for dementia research

Authors
Paul M Matthews, Naomi E Allen, Stephanie Debette, Aiden Doherty, Gwenaëlle Douaud, Eugene P Duff, Paul Elliott, Evelynne S Fulda, Anastasia Ilina, Quentin Le Grand, Adam J Lewandowski, Rebecca Mahoney, Karla Miller, Cecilia Rodriguez, Martin K Rutter, Cynthia Sandor, Rebecca Sims, Stephen M Smith, Chaoyue Wang
Author Correction: UK Biobank at 20 - a growing, global resource for dementia research
JAMA network open
Published

Plasma Biomarkers and Clinical Outcomes in Early-Onset Dementia

Authors
Hyemin Jang, Sun Min Lee, Hee Jin Kim, Na-Yeon Jung, Henrik Zetterberg, Kaj Blennow, Liana G Apostolova, So Young Moon, Eun-Joo Kim, Longitudinal Study of Early-Onset Dementia and Family Members (LEAF) Investigators
Plasma Biomarkers and Clinical Outcomes in Early-Onset Dementia
European journal of nuclear medicine and molecular imaging
Published

The Dementias Platform UK PET/MR harmonisation and test-retest study: assessment of PET repeatability and reproducibility across the national network

Authors
Pawel J Markiewicz, Gerard Thompson, Joanna M Wardlaw, Catriona Wimberley, Craig Ritchie, John-Paul Taylor, David Brooks, Ross Maxwell, Michael Firbank, Nigel Hoggard, Li Su, Jim Wild, Philip Hillel, Victoria Rhodes-Bradford, Laura M Parkes, John T O'Brien, Stephen F Carter, Franklin I Aigbirhio, Tim Fryer, Paul M Matthews, Paresh Malhotra, Gabrielle Grey, Will Hallett, Dilek Ocal, John C Dickson, Enrico De Vita, David L Thomas, Nick C Fox, Giorgios Krokos, Jane E Mackewn, Paul Marsden, Alexander Hammers, Karl Herholz, Frederik Barkhof, Julian C Matthews
The Dementias Platform UK PET/MR harmonisation and test-retest study: assessment of PET repeatability and reproducibility across the national network
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published

Temporal Interference Stimulation Enhances Neural Regeneration

Authors
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo-Lara, Bethany Geary, Elena Faillace, Shirine Merlo-Nikpay Aslie, Marcelina Wojewska, Maria Otero-Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre-Abarrategui, Rylie Green, Nir Grossmann
Temporal Interference Stimulation Enhances Neural Regeneration