Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

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- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Brain communications
Published

Stable isotope labelling kinetics of neurofilament light

Authors
Claire A Leckey, Tatiana A Giovannucci, John B Coulton, Yingxin He, Chihiro Sato, Nupur Ghoshal, Tharini Vignarajah, Zane Jaunmuktane, Nicolas R Barthélemy, Henrik Zetterberg, Donald L Elbert, Kevin Mills, Selina Wray, Randall J Bateman, Ross W Paterson
Stable isotope labelling kinetics of neurofilament light
Brain communications
Published

Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy

Authors
Noah L Shapiro, Peter Simon Jones, Elijah Mak, Kamen A Tsvetanov, Julia Goddard, Davi S Vontobel, Robert Durcan, Leonidas Chouliaras, Tim Fryer, Young T Hong, Franklin Aigbirhio, Amanda Heslegrave, Nicolai Franzmeier, Matthias Brendel, Henrik Zetterberg, John T O'Brien, James B Rowe, Maura Malpetti
Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy
Frontiers in neuroscience
Published

Saliva phosphorylated tau concentration is not associated with Alzheimer's disease, cerebrospinal fluid or blood biomarkers

Authors
Helena Sophia Gleerup, Federica Sanna, Srinivas Koutarapu, Juan Lantero-Rodriguez, Laia Montoliu-Gaya, Jörg Hanrieder, Gunnar Brinkmalm, Thomas K Karikari, Joel Simren, Peter Høgh, Kaj Blennow, Steen Gregers Hasselbalch, Henrik Zetterberg, Nicholas J Ashton, Anja Hviid Simonsen
Saliva phosphorylated tau concentration is not associated with Alzheimer's disease, cerebrospinal fluid or blood biomarkers
Nature
Published

Prevalence of Alzheimer's disease pathology in the community

Authors
Dag Aarsland, Anita Lenora Sunde, Diego A Tovar-Rios, Antoine Leuzy, Tormod Fladby, Henrik Zetterberg, Kaj Blennow, Kübra Tan, Giovanni De Santis, Yara Yakoub, Burak Arslan, Hanna Huber, Ilaria Pola, Lana Grötschel, Guglielmo Di Molfetta, Håvard K Skjellegrind, Geir Selbaek, Nicholas J Ashton
Prevalence of Alzheimer's disease pathology in the community
The Lancet. Respiratory medicine
Published

Blood biomarkers for the prediction of outcome after cardiac arrest: an international prospective observational study within the Targeted Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

Authors
Marion Moseby-Knappe, Helena Levin, Susann Ullén, Henrik Zetterberg, Kaj Blennow, Alice Lagebrant, Josef Dankiewicz, Janus C Jakobsen, Gisela Lilja, Alistair D Nichol, Glenn Eastwood, Kate Ainscough, Matthew J C Thomas, Anders M Grejs, Thomas R Keeble, Christian Rylander, Joachim Düring, Matt P Wise, Jan Hovdenes, Christian Storm, Ola Borgquist, Alain Cariou, Nicolas Deye, Jean-Baptiste Lascarrou, Jonathan Bannard-Smith, Johan Undén, Philippe Vignon, Stéphane Legriel, Ondřej Šmíd, David Pogson, Jiri Karasek, Peter J McGuigan, Michael Joannidis, Hans Kirkegaard, Jeremy Bewley, Steffen Christensen, Maria Rita Maccaroni, Anna Valerianova, Andreas Lundin, Anna Lybeck, Christoph Leithner, Filip Varhaník, Katie Sweet, Andrew Walden, Hans Friberg, Tobias Cronberg, Niklas Nielsen, TTM2 biobank study investigators
Blood biomarkers for the prediction of outcome after cardiac arrest: an international prospective observational study within the Targeted Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial
Fluids and barriers of the CNS
Published

The relationship between CSF/serum immunoglobulin and albumin ratio across laboratories: a retrospective, multi-center study

Authors
Harald Hegen, Ulf Andreasson, Juan J Archelos-Garcia, Gerhard Bachmaier, Kaj Blennow, Gabriel Bsteh, Isabelle Hubeek, Michael Khalil, Jens Kuhle, H Bea Kuiperij, Jan Lycke, Igal Rosenstein, Charlotte E Teunissen, Marcel M Verbeek, Michel Willemsen, Henrik Zetterberg, Janette Walde, Florian Deisenhammer
The relationship between CSF/serum immunoglobulin and albumin ratio across laboratories: a retrospective, multi-center study
Scientific reports
Published

Integrative analysis of AT classification, plasma biomarkers, and cognitive trajectories across diverse dementia syndromes

Authors
Jihwan Yun, Min Young Chun, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J Ashton, Daeun Shin, Soyeon Yoon, Heejin Yoo, Jun Pyo Kim, Hongki Ham, Yuna Gu, Hee Jin Kim, Seung Hwan Moon, Hanna Cho, Jae Yong Choi, Byung Hyun Byun, Su Yeon Park, Jeong Ho Ha, Duk L Na, Sang Won Seo, Hyemin Jang
Integrative analysis of AT classification, plasma biomarkers, and cognitive trajectories across diverse dementia syndromes
Acta neuropathologica
Published

Confirmation of p-tau Ser356's association with Alzheimer's disease pathology and lowering in response to WZ4003 treatment in brain slice cultures. Reply to: "Phospho-tau Ser356 is mostly confined to pre-NFT neurons in Alzheimer's pathology"

Authors
Lewis W Taylor, Elizabeth M Simzer, Lauren F P Young, Kristján Holt, Tara L Spires-Jones, Claire S Durrant
Confirmation of p-tau Ser356's association with Alzheimer's disease pathology and lowering in response to WZ4003 treatment in brain slice cultures. Reply to: "Phospho-tau Ser356 is mostly confined to pre-NFT neurons in Alzheimer's pathology"
Nature communications
Published

Publisher Correction: A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics

Authors
Yuki Kamijo, Philipp Mächler, Natalie Ness, Cong Quang Vu, Tsukasa Kusakizako, Jamsad Mannuthodikayil, Zaneta Ku, Marc Boisvert, Ekaterina Grebenik, Ikumi Miyazaki, Rina Hashizume, Haruaki Sato, Rui Liu, Yukiko Hori, Taisuke Tomita, Tetsuro Katayama, Akihiro Furube, Gabriela Caraveo, Marie-Eve Paquet, Mikhail Drobizhev, Osamu Nureki, Satoshi Arai, Marco Brancaccio, Robert E Campbell, David Kleinfeld, Yusuke Nasu
Publisher Correction: A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics