Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

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Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Resuscitation plus
Published
Neurofilament light chain for assessment of brain injury in four porcine cardiac arrest models
Authors
Olof Persson, Attila Frigyesi, Anna Valerianova, Mikuláš Mlček, Renaud Tissier, Fanny Lidouren, Matthias Kohlhauer, Giuseppe Ristagno, Aurora Magliocca, Francesca Fumagalli, Kaj Blennow, Henrik Zetterberg, Mohamad Hakam Tiba, Cindy H Hsu, Thomas H Sanderson, Robert Neumar, Hans Friberg
Neurofilament light chain for assessment of brain injury in four porcine cardiac arrest models
GeroScience
Published
Parental longevity and polygenic longevity scores in relation to ageing-related factors in a population of 70-year-olds followed over six years: The Gothenburg H70 Birth Cohort Study
Authors
Nazib M Seidu, Lina Rydén, Johan Skoog, Jessica Samuelsson, Silke Kern, Margda Waern, Henrik Zetterberg, Henne Holstege, Hanna Falk Erhag, Eric Westman, Ingmar Skoog
Parental longevity and polygenic longevity scores in relation to ageing-related factors in a population of 70-year-olds followed over six years: The Gothenburg H70 Birth Cohort Study
Acta neuropathologica
Published
Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer's vulnerability
Authors
Bernard Mulvey, Heena R Divecha, Madhavi Tippani, Svitlana V Bach, Rahul Bharadwaj, Ishbel Del Rosario, Sarah E Maguire, Ryan A Miller, Aaron J Salisbury, Atharv Chandra, Beau A Oster, Kelsey D Montgomery, Sang Ho Kwon, Haya A Algrain, Alexis R Papariello, Louise A Huuki-Myers, Joel E Kleinman, Leonardo Collado-Torres, Thomas M Hyde, Shizhong Han, Stephanie C Hicks, Daniel R Weinberger, Stephanie C Page, Kristen R Maynard, Keri Martinowich
Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer's vulnerability
Alzheimer's & dementia (New York, N. Y.)
Published
Remote digital cognitive assessment in a trial-ready Alzheimer's disease cohort: A scalable approach for early intervention studies
Authors
Andrew J Aschenbrenner, Hannah Wilks, Matthew Welhaf, Samhita Katteri, Sarah H Stout, Martin J Sliwinski, Tammie L S Benzinger, Brian Gordon, Yan Li, Richard J Perrin, Alan Renton, Guoqiao Wang, Chengjie Xiong, Christopher H van Dyck, Ricardo Allegri, William S Brooks, Jacob A Bechara, Suman Jayadev, Johannes Levin, Catherine J Mummery, Raquel Sanchez-Valle, David Aguillon, Eric M McDade, Randall J Bateman, Dominantly Inherited Alzheimer Network Trials Unit (DIAN‐TU), Jason Hassenstab
Remote digital cognitive assessment in a trial-ready Alzheimer's disease cohort: A scalable approach for early intervention studies
Brain : a journal of neurology
Published
Progress towards a biotypic biomarker profile for amyotrophic lateral sclerosis-frontotemporal spectrum disorders
Authors
Michael J Strong, Neil Donison, Ammar Al-Chalabi, Bradley Boeve, Elizabeth C Finger, Henne Holstege, Edward D Huey, Edward B Lee, Sarah J Marzi, Caroline McHutchison, Corey T McMillan, Markus Otto, Leonard Petrucelli, Mercedes Prudencio, Tanya Simuni, Maria Carmela Tartaglia, Martin R Turner, Philip Van Damme, David A Wolk
Progress towards a biotypic biomarker profile for amyotrophic lateral sclerosis-frontotemporal spectrum disorders
NPJ dementia
Published
Blood-based biomarkers of Alzheimer's disease and neurodegeneration in an indigenous African cohort using both Simoa and NULISA platforms
Authors
Tolulope Akinyemi, Ilaria Pola, Kubra Tan, Oladotun Olalusi, Joseph Yaria, Gabriel Ogunde, Wiebke Traichel, Nesrine Rahmouni, Olabode Oguntiloye, Ayotomiwa Fagbemi, Eniola Cadmus, Femi Popoola, Joseph Therriault, Mayowa Ogunronbi, Dorcas Olujobi, Olaoluwa Famuyiwa, Joshua Akinyemi, Tharick Pascoal, Mayowa Owolabi, Pedro Rosa-Neto, Chinedu T Udeh-Momoh, Olusola Ladokun, Roman Romero-Ortuno, Adesola Ogunniyi, Brian Lawlor, Rajesh Kalaria, Henrik Zetterberg, Andrea L Benedet, Rufus Akinyemi
Blood-based biomarkers of Alzheimer's disease and neurodegeneration in an indigenous African cohort using both Simoa and NULISA platforms
Research square
Published
Integrated B and T Cell Repertoire Analysis Reveals Organized but Heterogeneous Adaptive Immunity in Chronic Experimental Stroke
Authors
Sangeetha Senthil Kumar, Danielle A Becktel, Erin D Chapman, Susan A Whitman, Rachel Crumpacker, Jacob C Zbesko, Daniel Berchtold, Claudia Dames, María I Cuartero, Alicia Garcia-Culebras, Lizi M Hegarty, Gaia Brezzo, Jennifer E Goertz, Kristy A Zera, Craig J Smith, Stuart M Allan, Christian Meisel, Andreas Meisel, María Ángeles Moro, Barry W McColl, Josef Anrather, Marion S Buckwalter, Helena W Morrison, Rick G Schnellmann, Kristian P Doyle
Integrated B and T Cell Repertoire Analysis Reveals Organized but Heterogeneous Adaptive Immunity in Chronic Experimental Stroke
Science advances
Published
Activation of transposable elements is linked to a region- and cell type-specific interferon response in Parkinson's disease
Authors
Raquel Garza, Anita Adami, Arun Thiruvalluvan, Sasvi Wijesinghe, Annabel Curle, Oliver Tam, Talitha Forcier, Danai A Lagka, Nina L Kazakou, Diahann A M Atacho, Yogita Sharma, Vivien Horvath, Sara Bermudez, Jenny Johansson, Daniel B Rainbow, Laura Castilla-Vallmanya, Joanne L Jones, Annelies Quaegebeur, Molly Gale Hammell, Agnete Kirkeby, Roger A Barker, Johan Jakobsson
Activation of transposable elements is linked to a region- and cell type-specific interferon response in Parkinson's disease