Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Journal of neurochemistry
Published

Circulating Sphingomyelins Correlate With Plasma T-Tau in Cognitively Unimpaired Older Adults at Risk of Developing Alzheimer's Disease

Authors
Tahmida Sharmin, James D Doecke, Pratishtha Chatterjee, Steve Pedrini, Hamid R Sohrabi, Nicholas J Ashton, Henrik Zetterberg, Manohar L Garg, Kaj Blennow, Ralph N Martins
Circulating Sphingomyelins Correlate With Plasma T-Tau in Cognitively Unimpaired Older Adults at Risk of Developing Alzheimer's Disease
NPJ Parkinson's disease
Published

Identifying maximal beta power from directional subthalamic local field potentials in Parkinson's disease

Authors
Jennifer K Behnke, Robert L Peach, Moritz Gerster, Richard M Köhler, Jeroen G V Habets, Johannes L Busch, Varvara Mathiopoulou, Jonathan Kaplan, Lucia K Feldmann, Juliette Vivien, Chi Wang Ip, Gerd-Helge Schneider, Katharina Faust, Patricia Krause, Andrea A Kühn
Identifying maximal beta power from directional subthalamic local field potentials in Parkinson's disease
Science (New York, N.Y.)
Published

Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration

Authors
Katie E Copley, Jocelyn C Mauna, Helen L Danielson, Qizan Chen, Busra Ozguney, Marilyn Ngo, Longxin Xie, Ashleigh Smirnov, Matt Davis, Leland Mayne, Miriam Linsenmeier, Jack D Rubien, Cristian A Bergmann, Bede Portz, Bo Lim Lee, Hana M Odeh, Longsheng Lai, Yi-Wei Chang, Martina Hallegger, Jernej Ule, Piera Pasinelli, Yan Poon, Jeetain Mittal, Nicolas L Fawzi, Ben E Black, Christopher J Donnelly, Brigid K Jensen, James Shorter
Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
Nature communications
Published

Alzheimer's Disease blood biomarkers measured through remote capillary sampling correlate with cognition in older adults

Authors
Anne Corbett, Millie Sander-Long, Nicholas J Ashton, Hanna Huber, Jakub Vavra, Luisa Sophie Braun-Wohlfahrt, Henrik Zetterberg, Laia Montoliu-Gaya, Jeffrey Cummings, Freya Bateman, Christine Davis, Clive Ballard
Alzheimer's Disease blood biomarkers measured through remote capillary sampling correlate with cognition in older adults
Alzheimer's & dementia (Amsterdam, Netherlands)
Published

Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS

Authors
Dustin B Hammers, Angelina Polsinelli, Ani Eloyan, Alexander Taurone, Maryanne Thangarajah, Tatiana Foroud, Sujuan Gao, Laurel Beckett, Renaud La Joie, Alexandra Touroutoglou, Prashanthi Vemuri, Henrik Zetterberg, Kaj Blennow, Sára Nemes, Ralitsa Kostadinova, Paul Aisen, Kelly N Nudelman, Kala Kirby, Alireza Atri, David Clark, Gregory S Day, Ranjan Duara, Neill R Graff-Radford, Ian Grant, Lawrence S Honig, Erik C B Johnson, David T Jones, Joseph C Masdeu, Mario F Mendez, Leila Parand, Kyle Womack, Erik Musiek, Chiadi U Onyike, Meghan Riddle, Emily Rogalski, Stephen Salloway, Sharon J Sha, Raymond Scott Turner, Thomas S Wingo, David A Wolk, Maria C Carrillo, Gil D Rabinovici, Bradford C Dickerson, Jeffrey L Dage, Liana G Apostolova, LEADS Consortium
Criterion and convergent validity of plasma biomarkers in early-onset Alzheimer's disease: Initial findings from LEADS
Age and ageing
Published

Factors influencing implementation of an Alzheimer's disease blood test among UK old age psychiatrists: mixed-methods study using the theoretical domains framework

Authors
Hazan Jemma, Mitchell Mealing, Fabiana Lorencatto, Penny Rapaport, Ashvini Keshavan, Jonathan M Schott, Joanne Rodda, Robert Howard
Factors influencing implementation of an Alzheimer's disease blood test among UK old age psychiatrists: mixed-methods study using the theoretical domains framework
Circulation
Published

Implications of Cranial Arterial Stenosis and Dolichoectasia for Cerebral Small-Vessel Disease Etiopathogenesis: Findings From a Prospective Mild Stroke Cohort

Authors
Fei Han, Una Clancy, Carmen Arteaga-Reyes, Michael J Thrippleton, Maria Del C Valdés Hernández, Daniela Jaime Garcia, Michael S Stringer, Ellen Backhouse, Francesca M Chappell, Yajun Cheng, Dillys Xiaodi Liu, Junfang Zhang, Angela C C Jochems, Eleni Sakka, Charlotte Jardine, Gayle Barclay, Donna McIntyre, Iona Hamilton, Rosalind Brown, Yi-Cheng Zhu, Fergus N Doubal, Joanna M Wardlaw
Implications of Cranial Arterial Stenosis and Dolichoectasia for Cerebral Small-Vessel Disease Etiopathogenesis: Findings From a Prospective Mild Stroke Cohort
Nature reviews. Neurology
Published

Author Correction: UK Biobank at 20 - a growing, global resource for dementia research

Authors
Paul M Matthews, Naomi E Allen, Stephanie Debette, Aiden Doherty, Gwenaëlle Douaud, Eugene P Duff, Paul Elliott, Evelynne S Fulda, Anastasia Ilina, Quentin Le Grand, Adam J Lewandowski, Rebecca Mahoney, Karla Miller, Cecilia Rodriguez, Martin K Rutter, Cynthia Sandor, Rebecca Sims, Stephen M Smith, Chaoyue Wang
Author Correction: UK Biobank at 20 - a growing, global resource for dementia research