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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

The journal of prevention of Alzheimer's disease
Published

Utility of plasma GFAP as a secondary endpoint for clinical trials in Alzheimer's disease

Authors
Sarah Abbas, Pamela C L Ferreira, Bruna Bellaver, Guilherme Povala, Francieli Rohden, Cristiano Schaffer Aguzzoli, Hussein Zalzale, João Pedro Ferrari-Souza, Douglas T Leffa, Firoza Z Lussier, Carolina Soares, Guilherme Bauer-Negrini, Markley Silva Oliveira-Junior, Matheus Scarpatto Rodrigues, Pampa Saha, Emma Ruppert, Marina Scop Medeiros, Cécile Tissot, Joseph Therriault, Nesrine Rahmouni, Stijn Servaes, Andrea L Benedet, Nicholas J Ashton, Dana L Tudorascu, Serge Gauthier, Helmet Karim, Chang Hyung Hong, Hyun Woong Roh, Eduardo R Zimmer, Thomas K Karikari, Henrik Zetterberg, Kaj Blennow, Anum Saeed, Sang Joon Son, Pedro Rosa-Neto, Tharick Pascoal, for Alzheimer’s Disease Neuroimaging Initiative
Utility of plasma GFAP as a secondary endpoint for clinical trials in Alzheimer's disease
Nature neuroscience
Published

Author Correction: Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus

Authors
Kyoko Tossell, Xiao Yu, Panagiotis Giannos, Berta Anuncibay Soto, Mathieu Nollet, Raquel Yustos, Giulia Miracca, Mikal Vicente, Andawei Miao, Bryan Hsieh, Ying Ma, Alexei L Vyssotski, Tim Constandinou, Nicholas P Franks, William Wisden
Author Correction: Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus
Scientific reports
Published

Synaptic markers are associated with cognitive decline after accounting for amyloid burden among an at-risk Alzheimer's disease cohort

Authors
Elizabeth M Planalp, Rebecca E Langhough, Erin M Jonaitis, Carol A Van Hulle, Rachael E Wilson, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Ozioma C Okonkwo, Barbara B Bendlin, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C Johnson
Synaptic markers are associated with cognitive decline after accounting for amyloid burden among an at-risk Alzheimer's disease cohort
Movement disorders : official journal of the Movement Disorder Society
Published

Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients

Authors
Paula Saffie-Awad, Abraham Moller, Kensuke Daida, Pilar Alvarez Jerez, Zhongbo Chen, Zachary B Anderson, Mariam Isayan, Kimberly Paquette, Sophia B Gibson, Madison Fulcher, Abigail Miano-Burkhardt, Laksh Malik, Breeana Baker, Paige Jarreau, Henry Houlden, Mina Ryten, Bida Gu, Mark J P Chaisson, Danny E Miller, Pedro Chaná-Cuevas, Cornelis Blauwendraat, Andrew B Singleton, Kimberley J Billingsley
Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients
Science advances
Published

Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration

Authors
Michael R Duggan, Shuojia Yang, Gabriela T Gomez, Yuhan Cui, Ana W Capuano, Jingsha Chen, Zhijian Yang, Junhao Wen, Guray Erus, Shannon M Drouin, David Zweibaum, Qu Tian, Julián Candia, Murat Bilgel, Alexandria Lewis, Abhay Moghekar, Nicholas J Ashton, Przemysław R Kac, Thomas K Karikari, Kaj Blennow, Henrik Zetterberg, Brion S Maher, Adam P Spira, Logan Dumitrescu, Timothy J Hohman, Rebecca F Gottesman, Christos Davatzikos, David A Bennett, Josef Coresh, Luigi Ferrucci, Susan M Resnick, Robert Yolken, Keenan A Walker
Proteomic signatures of corona and herpes viral antibodies identify IGDCC4 as a mediator of neurodegeneration
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

Authors
Bess Frost, James B Rowe, Rufus O Akinyemi, Jose F Abisambra, Nicholas J Ashton, Matthias Brendel, Luc Buée, David Butler, Maria C Carrillo, Peter Chung, Claire D Clelland, Sarah L DeVos, Kristophe Diaz, Rebecca M Edelmayer, Fanny M Elahi, Ratnavalli Ellajosyula, Colin Ewen, Igor Camargo Fontana, Marie-Christine Galas, Oskar Hansson, Günter Höglinger, Kanta Horie, Agustín Ibanez, Linde Jacobs, Mahmoud B Maina, Maura Malpetti, Eric McDade, Will McEwan, Laia Montoliu-Gaya, Catherine J Mummery, Miranda E Orr, Jonathan D Rohrer, Amy Rommel, Carlos Sastre, Tara L Spires-Jones, Boon Lead Tee, Tim J Viney, Jamie M Walker, Susanne Wegmann, Kristin Wildsmith, Ravi Yadav, Simin Mahinrad, Claire Sexton
Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Repeated plasma p-tau217 measurements to monitor clinical progression heterogeneity

Authors
Bjørn-Eivind Kirsebom, Fernando Gonzalez-Ortiz, Sinthujah Vigneswaran, Geir Bråthen, Ragnhild Eide Skogseth, Berglind Gísladóttir, Peter Harrison, Jonas Alexander Jarholm, Lene Pålhaugen, Arvid Rongve, Per Selnes, Betty Tjims, Michael Turton, Argonde C Van Harten, Knut Waterloo, Henrik Zetterberg, Tormod Fladby, Kaj Blennow
Repeated plasma p-tau217 measurements to monitor clinical progression heterogeneity
Neurology
Published

Association of Self-Reported Sleep Metrics With Imaging Markers of Small Vessel Disease and Cognition in Patients With TIA or Mild Stroke

Authors
Dillys Xiaodi Liu, Mary Sau-Man Ip, David Chi-Leung Lam, Francesca M Chappell, Una Clancy, Daniela Jaime Garcia, Carmen Arteaga-Reyes, Maria Del C Valdés Hernández, Michael Thrippleton, Michael S Stringer, Yajun Cheng, Junfang Zhang, Fergus Doubal, Gary Kui Kai Lau, Joanna M Wardlaw
Association of Self-Reported Sleep Metrics With Imaging Markers of Small Vessel Disease and Cognition in Patients With TIA or Mild Stroke
JMIR aging
Published

Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study

Authors
Victoria Grace Gabb, Jonathan Blackman, Hamish Morrison, Haoxuan Li, Adrian Kendrick, Nicholas Turner, Rosemary Greenwood, Bijetri Biswas, Amanda Heslegrave, Elizabeth Coulthard
Longitudinal Remote Sleep and Cognitive Research in Older Adults With Mild Cognitive Impairment and Dementia: Prospective Feasibility Cohort Study