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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

JAMA network open
Published

Plasma Biomarkers and Clinical Outcomes in Early-Onset Dementia

Authors
Hyemin Jang, Sun Min Lee, Hee Jin Kim, Na-Yeon Jung, Henrik Zetterberg, Kaj Blennow, Liana G Apostolova, So Young Moon, Eun-Joo Kim, Longitudinal Study of Early-Onset Dementia and Family Members (LEAF) Investigators
Plasma Biomarkers and Clinical Outcomes in Early-Onset Dementia
European journal of nuclear medicine and molecular imaging
Published

The Dementias Platform UK PET/MR harmonisation and test-retest study: assessment of PET repeatability and reproducibility across the national network

Authors
Pawel J Markiewicz, Gerard Thompson, Joanna M Wardlaw, Catriona Wimberley, Craig Ritchie, John-Paul Taylor, David Brooks, Ross Maxwell, Michael Firbank, Nigel Hoggard, Li Su, Jim Wild, Philip Hillel, Victoria Rhodes-Bradford, Laura M Parkes, John T O'Brien, Stephen F Carter, Franklin I Aigbirhio, Tim Fryer, Paul M Matthews, Paresh Malhotra, Gabrielle Grey, Will Hallett, Dilek Ocal, John C Dickson, Enrico De Vita, David L Thomas, Nick C Fox, Giorgios Krokos, Jane E Mackewn, Paul Marsden, Alexander Hammers, Karl Herholz, Frederik Barkhof, Julian C Matthews
The Dementias Platform UK PET/MR harmonisation and test-retest study: assessment of PET repeatability and reproducibility across the national network
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published

Temporal Interference Stimulation Enhances Neural Regeneration

Authors
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo-Lara, Bethany Geary, Elena Faillace, Shirine Merlo-Nikpay Aslie, Marcelina Wojewska, Maria Otero-Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre-Abarrategui, Rylie Green, Nir Grossmann
Temporal Interference Stimulation Enhances Neural Regeneration
Alzheimer's research & therapy
Published

Genetic drivers of progression in Alzheimer's disease are distinct from disease risk

Authors
Celeste E Cohen, Shane Fernandez, Umran Yaman, Ahmad R Ehyaei, Eleftheria Kodosaki, Aydan Askarova, Tenielle Porter, Eleanor O'Brien, Australian Imaging Biomarkers and Lifestyle Study, Alzheimer’s Disease Neuroimaging Initiative, Paul Maruff, Alexi Nott, John A Hardy, Simon M Laws, Dervis A Salih, Maryam Shoai
Genetic drivers of progression in Alzheimer's disease are distinct from disease risk
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Mind the gap: obtaining reliable sleep estimates and the diagnostic value of sleep discrepancy in individuals with Alzheimer's disease and Lewy body disease

Authors
Victoria Grace Gabb, Jonathan Blackman, Hamish Duncan Morrison, Nicholas Turner, Amanda Heslegrave, Elizabeth Coulthard
Mind the gap: obtaining reliable sleep estimates and the diagnostic value of sleep discrepancy in individuals with Alzheimer's disease and Lewy body disease
Alzheimer's & dementia (Amsterdam, Netherlands)
Published

The relative contribution of modifiable and non-modifiable factors for determining cognition in mid-life individuals at risk for late-life Alzheimer's disease

Authors
Bolin Cao, Qing Qi, Siobhan Hutchinson, Damien Ferguson, Paresh Malhotra, Ivan Koychev, John T O'Brien, Katie Bridgeman, Craig W Ritchie, Brian Lawlor, Lorina Naci, PREVENT Dementia Investigators
The relative contribution of modifiable and non-modifiable factors for determining cognition in mid-life individuals at risk for late-life Alzheimer's disease
Nature
Published

Focal white matter lesions drive grey matter inflammation and synapse loss

Authors
Omar de Faria, Stavros Vagionitis, Andrea Lopez-Lopez, Michael Perry, Joseph Jo Yin Wong, Leslie Rodríguez-Kirby, Bastien Hervé, Balazs Viktor Varga, Eneritz Agirre, Sabrina Ghosh, Sebastian Timmler, Mert Yucel, Andrew T Setley, Kimberley Anne Evans, Tanja Mist Birgisdóttir, Sindri Gíslason, Yan Ting Ng, Courtney Kremler, Helene O B Gautier, Yasmine Kamen, Helena Pivonkova, Katrin Volbracht, Felix Hildebrand, Christian A Cepeda, Javier Rueda-Carrasco, Soyon Hong, George Malliaras, Sabine Dietmann, Gonçalo Castelo-Branco, Ragnhildur Thóra Káradóttir
Focal white matter lesions drive grey matter inflammation and synapse loss
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Aging-related matrix metallopeptidase 10 and osteopontin levels are associated with pathology, cognitive decline, and age at onset in Alzheimer's disease

Authors
Bryan Ng, Eleftheria Kodosaki, Elena Veleva, Ashvini Keshavan, Jonathan M Schott, Amanda J Heslegrave, Nick C Fox, Henrik Zetterberg
Aging-related matrix metallopeptidase 10 and osteopontin levels are associated with pathology, cognitive decline, and age at onset in Alzheimer's disease
Nature communications
Published

GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy

Authors
Jigyasha Timsina, Chenyang Jiang, Daniel L McCartney, Feifei Tao, Maria Carolina Dalmasso, Jenna Najar, Federica Anastasi, Olena Ohlei, Raquel Puerta Fuentes, Chenyu Yang, Joseph Bradley, Daniel Western, Muhammad Ali, Ciyang Wang, Chengran Yang, Ying Wu, Menghan Liu, John Budde, Julie Williams, Rebecca Mahoney, Atahualpa Castillo Morales, Timothy J Hohman, Logan Dumitrescu, Ting-Chen Wang, Niccolo' Tesi, Silke Kern, Margda Waern, Ingmar Skoog, Argonde van Harten, Yolande A L Pijnenburg, Wiesje M van der Flier, Pascual Sánchez-Juan, Eloy Rodriguez-Rodriguez, Luca Kleineidam, Oliver Peters, Anja Schneider, Fahri Küçükali, Céline Bellenguez, Benjamin Grenier-Boley, Sami Heikkinen, Itziar de Rojas, Dan Rujescu, Norbert Scherbaum, Lucrezia Hausner, Emrah Düzel, Timo Grimmer, Jens Wiltfang, Rik Vandenberghe, Sebastiaan Engelborghs, Stefanie Heilmann-Heimbach, Matthias Schmid, Thomas Tegos, Nikolaos Scarmeas, Oriol Dols-Icardo, Fermin Moreno, Jordi Pérez-Tur, María J Bullido, Raquel Sánchez-Valle, Victoria Álvarez, Pablo García-González, Pablo Mir, Luis M Real, Gerard Piñol-Ripoll, Jose María García-Alberca, Harro Seelaar, Inez Ramakers, Janne Papma, Marc Hulsman, Christoph Laske, Stefan Teipel, Josef Priller, Robert Perneczky, Katharina Buerger, Markus M Nöthen, Piotr Lewczuk, Johannes Kornhuber, Harald Hampel, Ina Giegling, Oliver Goldhardt, Janine Diehl-Schmid, Victor Andrade, Michael Mt Heneka, Lutz Frölich, Jonathan Vogelgsang, Caroline Graff, Hakan Thonberg, Abbe Ullgren, Goran Papenberg, Jean-François Deleuze, Carole Dufouil, Michael Wagner, Frank Jessen, Henne Holstege, Cornelia van Duijn, Thibaud Lebouvier, Olivier Hannon, Ville Leinonen, Hilkka Soininen, Sanna-Kaisa Herukka, Vilmantas Giedraitis, Malin Löwenmark, Lena Kilander, Patricia Genius, Blanca Rodríguez, Emma S Luckett, Arcadi Navarro, Amanda Cano, Marta Marquié, Kaj Blennow, Henrik Zetterberg, Alberto Lleo, Mercè Boada, Agustin Ruiz, Virginia Man-Yee Lee, Vivianna M Van Deerlin, Yuetiva Deming, Sterling C Johnson, Corinne D Engelman, Pau Pastor, Ignacio Alvarez, Elaine R Peskind, Amanda J Heslegrave, Andrew J Saykin, Kwangsik Nho, Suzanne E Schindler, John C Morris, David M Holtzman, Eric McDade, Alan E Renton, Alison Goate, Laura Ibanez, Matthias Riemenschneider, Marilyn S Albert, Simon M Laws, Tenielle Porter, Eleanor K O'Brien, Leslie M Shaw, Betty M Tijms, Martin Ingelsson, Pieter Jelle Visser, Mikko Hiltunen, Kristel Sleegers, Craig W Ritchie, Rebecca Sims, Michael Belloy, Jean-Charles Lambert, Natalia Vilor-Tejedor, Maria Victoria Fernández, Qingqin S Li, Michael W Nagle, Riccardo E Marioni, Alfredo Ramirez, Lars Bertram, Sven J van der Lee, Carlos Cruchaga
GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy