Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

man sitting on bed at night
- Research

Sleep problems could double risk of dementia in later life

People who experience sleep disorders are at greater risk of developing dementia and other neurodegenerative conditions later in life, new research led by Prof Valentina...

Learn more Sleep problems could double risk of dementia in later life
Scientific data
Published

The RESILIENT Dataset: Multimodal Monitoring of Ageing-Related Comorbidities and Cognitive Decline

Authors
Nathalia Céspedes Gómez, Yu Chen, Samaneh Kouchaki, Mahan Heydari, Alexandra Cairns, Sergio David Sierra Marín, Alexander Capstick, Jaye Somers, Kirsty Harris, Wilson Wen Bin Goh, Chloe Walsh, Jessica True, Olga Balazikova, Ramin Nilforooshan, Payam Barnaghi
The RESILIENT Dataset: Multimodal Monitoring of Ageing-Related Comorbidities and Cognitive Decline
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Predicting cognitive decline with amyloid-PET, plasma p-tau217, Aβ42/40, and p-tau217/Aβ42 in a community-based cohort - relevance for clinical trial enrollment

Authors
Dario Bachmann, Maha Wybitul, Andreas Buchmann, Christoph Gericke, Antje Saake, Sandro Studer, Katrin Rauen, Esmeralda Gruber, Kaj Blennow, Henrik Zetterberg, Roger M Nitsch, Christoph Hock, Valerie Treyer, Anton Gietl
Predicting cognitive decline with amyloid-PET, plasma p-tau217, Aβ42/40, and p-tau217/Aβ42 in a community-based cohort - relevance for clinical trial enrollment
Current biology : CB
Published

The blood-brain barrier

Authors
Audrey Chagnot, Axel Montagne
The blood-brain barrier
European journal of nuclear medicine and molecular imaging
Published

Comparing and combining TSPO-PET tracers in tauopathies

Authors
Harry Crook, Nicolai Franzmeier, Nesrine Rahmouni, Johannes S Gnörich, Tim D Fryer, Young T Hong, Sebastian N Roemer-Cassiano, Carla Palleis, Alexandra Strauss, P Simon Jones, Franklin I Aigbirhio, Robert Hopewell, Boris-Stephan Rauchmann, Gassan Massarweh, Robert Perneczky, Johannes Levin, Günter U Höglinger, James B Rowe, John T O'Brien, Pedro Rosa-Neto, Matthias Brendel, Maura Malpetti
Comparing and combining TSPO-PET tracers in tauopathies
Neurology
Published

Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease

Authors
David López-Martos, Marc Suárez-Calvet, Marta Milà-Alomà, Juan Domingo Gispert, Gemma Salvadó, Anna Brugulat-Serrat, Mahnaz Shekari, Carolina Minguillon, Henrik Zetterberg, Kaj Blennow, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides, ALFA study
Longitudinal Associations of Multimodal Core 1 Alzheimer Disease Biomarkers With Cognition in Aging and Preclinical Alzheimer Disease
Molecular neurodegeneration
Published

Synaptic dysfunction and glial activation markers throughout aging and early neurodegeneration: a longitudinal CSF biomarker-based study

Authors
Mariana I Muñoz-García, Yuetiva Deming, Ferran Lugo-Hernández, Sterling Johnson, Sanjay Asthana, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Cynthia Carlsson, Ozioma C Okonkwo, David Pérez-Martinez, Alberto Villarejo-Galende, Kaj Blennow, Marc Suárez-Calvet, Henrik Zetterberg, Barbara B Bendlin, Estrella Morenas-Rodríguez
Synaptic dysfunction and glial activation markers throughout aging and early neurodegeneration: a longitudinal CSF biomarker-based study
Schizophrenia research
Published

The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia

Authors
Maria E Dimitriades, Eve Schumacher, Janani Arudchelvam, Sara Fattinger, Salome Kurth, Fiona Pugin, Flavia Wehrle, Valeria Jaramillo, Carina Volk, Sven Leach, Ashura Buckley, David I Driver, Andjela Markovic, Judith L Rapoport, Leila Tarokh, Reto Huber, Miriam Gerstenberg
The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published

Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease

Authors
Eleonora M Vromen, Senne B Lageman, Johan Gobom, Rik van der Kant, Valerija Dobricic, Lars Bertram, Johannes Streffer, Simon Lovestone, Stephanie J B Vos, Mikel Tainta, Yvonne Freund-Levi, Lutz Frölich, Julius Popp, Gwendoline Peyratout, Magda Tsolaki, Frans Verhey, Rik Vandenberghe, Jolien Schaeverbeke, Kaj Blennow, Sven J van der Lee, Philip Scheltens, Yolande A L Pijnenburg, Wiesje M van der Flier, Charlotte E Teunissen, Henrik Zetterberg, Pieter Jelle Visser, Betty Tijms
Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease