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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Nature aging
Published
Blood-based AT(N) biomarkers for Alzheimer's disease and frontotemporal lobar degeneration in Latin America
Authors
Ariel Caviedes, Felipe Cabral-Miranda, Paulina Orellana, Hernán Hernández, Fernando Henríquez, Raul Gonzalez-Gomez, Matias Pizarro, Joaquin Migeot, Carolina Ochoa-Rosales, Carolina Gonzalez-Silva, Nickole Marin-Diaz, Carlos Coronel-Oliveros, Hernando Santamaría-García, Danilo Carmona, Adolfo M García, Andrea Slachevsky, Andrew Singleton, Andy Yue Qi, Brian Lawlor, Bruce Miller, Catherine Dhooge, Caroline Pantazis, Chinedu T Udeh-Momoh, David Aguillón, Diana L Matallana, Eduardo R Zimmer, Elisa de Paula França Resende, Francesca R Farina, Francisca Cabello, Francisco Lopera, Henrik Zetterberg, José Alberto Avila-Funes, Juliana Acosta-Uribe, Katherine L Possin, Kenneth S Kosik, Kun Hu, Leonel T Takada, Maira Okada de Oliveira, Marcelo Adrian Maito, Marc Suárez-Calvet, Maria E Godoy, Maria Isabel Behrens, Mario A Parra, Marta Del Campo, Martin Bruno, Nancy Gelvez, Natalia Pozo-Castro, J Nicholas Cochran, Nilton Custodio, Rodrigo Ortega, Rodrigo Santibanez, Rolando de la Cruz, Rosa Montesinos, Sarah McDonagh, Sara Bandres-Ciga, Shireen Javandel, Sonia M D Brucki, Stefanie D Pina-Escudero, Victor Valcour, Ziyi Li, Jennifer S Yokoyama, Agustin Ibañez, Claudia Duran-Aniotz, Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat)
Blood-based AT(N) biomarkers for Alzheimer's disease and frontotemporal lobar degeneration in Latin America
J Cereb Blood Flow Metab
Published
CAA-related enlarged perivascular spaces are associated with abnormal angioarchitecture in human brain tissue: A key role for white matter atrophy?
Authors
Marion Giraud, Dae Hee Yun, Leon P Munting, Kwanghun Chung, Brian J Bacskai, Steven M Greenberg, Matthew P Frosch, Alain Goriely, Susanne J van Veluw, Sylvie Lorthois
CAA-related enlarged perivascular spaces are associated with abnormal angioarchitecture in human brain tissue: A key role for white matter atrophy?
Science (New York, N.Y.)
Published
Myelin sheaths in the central nervous system can withstand damage and dynamically remodel
Authors
Donia Arafa, Julia van de Korput, Philipp N Braaker, Kieran P Higgins, Niels R C Meijns, Katy L H Marshall-Phelps, Julia Meng, Daniel Soong, Eleonora Scalia, Kyle Lathem, Marcus Keatinge, Claire Richmond, Anna Klingseisen, Marja Main, Sarah A Neely, David W Hampton, Greg J Duncan, Geert J Schenk, Marie Louise Groot, Siddharthan Chandran, Ben Emery, Antonio Luchicchi, Maarten H P Kole, Anna C Williams, David A Lyons
Myelin sheaths in the central nervous system can withstand damage and dynamically remodel
Nature communications
Published
FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing
Authors
Pierre Parutto, Yutong Yuan, Valentina Davì, Roger Pons-Lanau, Svenja Ebeling, Karnika Gupta, Francesca Bottanelli, Maria F Garcia-Parajo, Felix Campelo, Clemens F Kaminski, Joseph E Chambers, Jonathon Nixon-Abell, Edward Avezov
FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Plasma biomarker progression across the Alzheimer's disease amyloid beta and tau positron emission tomography trajectories
Authors
Rodrigo Cánovas, Christopher J Fowler, Azadeh Feizpour, Vincent Dóre, Pierrick Bourgeat, Ziad S Saad, Gallen Triana-Baltzer, Hartmuth C Kolb, Manu Vandijck, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Jurgen Fripp, Simon Laws, Anthony W Bannon, Kaj Blennow, Henrik Zetterberg, Stephanie Rainey-Smith, Sulantha Mathotaarachchi, Christopher C Rowe, Colin L Masters, James D Doecke, AIBL Research Group
Plasma biomarker progression across the Alzheimer's disease amyloid beta and tau positron emission tomography trajectories
Journal of neurochemistry
Published
N-Truncated Superoxide Dismutase-1 in Cerebrospinal Fluid Is Folded and Active
Authors
Laura Leykam, Karin M E Forsberg, Peter M Andersen, Thomas Brännström, Sophia Weiner, John Rönnholm, Kaj Blennow, Henrik Zetterberg, Stefan L Marklund, Johan Gobom, Per Zetterström
N-Truncated Superoxide Dismutase-1 in Cerebrospinal Fluid Is Folded and Active
JAMA network open
Published
Blood-Based Analysis of Different Tau Variants in Patients With Multiple Traumatic Injuries
Authors
Rebecca Halbgebauer, Fernando Gonzalez-Ortiz, Benjamin Mayer, Claudius Berger, Christian Bergmann, Helen Rinderknecht, Eberhard Barth, Lisa Wohlgemuth, Marco Mannes, Markus Otto, Hayrettin Tumani, Borna Relja, Florian Gebhard, Markus Huber-Lang, Henrik Zetterberg, Steffen Halbgebauer, Kaj Blennow
Blood-Based Analysis of Different Tau Variants in Patients With Multiple Traumatic Injuries
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published
Quantitative susceptibility mapping of the brain is associated with inflammatory changes in Alzheimer's disease related areas
Authors
Seyyed Ali Hosseini, Stijn Servaes, Arthur C Macedo, Etienne Aumont, Nesrine Rahmouni, Tevy Chan, Joseph Therriault, Lydia Trudel, Brandon Hall, Yi-Ting Wang, Jaime Fernandez Arias, Gleb Bezgin, Yansheng Zheng, Marina P Gonçalves, Kely Quispialaya Socualaya, Marcel S Woo, Cécile Tissot, Delphine Oliva-Lopez, Jieying Li, Stuart Mitchell, Aurélie Lebrun, Robert Hopewell, Sanjeev Chawla, Vladimir Fonov, Gassan Massarweh, Yasser Iturria Medina, Jean-Paul Soucy, Maxime Montembeault, Paolo Vitali, Kaj Blennow, Thomas K Karikari, Andréa L Benedet, Nicholas J Ashton, Henrik Zetterberg, Tharick A Pascoal, Serge Gauthier, Jesse Klostranec, Hangwei Zhuang, Junghun Cho, D Louis Collins, Yi Wang, David A Rudko, Pedro Rosa-Neto
Quantitative susceptibility mapping of the brain is associated with inflammatory changes in Alzheimer's disease related areas
Molecular neurodegeneration
Published
Targeting tau in Alzheimer's Disease: rationale, approach and challenges
Authors
Aram Aslanyan, Martha S Foiani, Tatiana A Giovannucci, Eric McDade, Karen E Duff, Catherine J Mummery, Michael Schöll, Kristin R Wildsmith, Ross W Paterson
Targeting tau in Alzheimer's Disease: rationale, approach and challenges
Human brain mapping
Published
segcsvd<sub>PVS</sub>: A Convolutional Neural Network-Based Tool for Quantification of Enlarged Perivascular Spaces (PVS) on T<sub>1</sub>-Weighted Images
Authors
Erin Gibson, Joel Ramirez, Lauren Abby Woods, Stephanie Berberian, Julie Ottoy, Christopher J M Scott, Vanessa Yhap, Fuqiang Gao, Roberto Duarte Coello, Maria Valdes Hernandez, Anthony E Lang, Carmela M Tartaglia, Sanjeev Kumar, Malcolm A Binns, Robert Bartha, Sean Symons, Richard H Swartz, Mario Masellis, Navneet Singh, Bradley J MacIntosh, Joanna M Wardlaw, Sandra E Black, ONDRI Investigators, ADNI, CAHHM Investigators, CAIN Investigators, colleagues from the Foundation Leducq Transatlantic Network of Excellence, Andrew S P Lim, Maged Goubran
segcsvd<sub>PVS</sub>: A Convolutional Neural Network-Based Tool for Quantification of Enlarged Perivascular Spaces (PVS) on T<sub>1</sub>-Weighted Images