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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Frontiers in aging neuroscience
Published

Machine learning-based personalized composite score dissects risk and protective factors for cognitive and motor function in older participants

Authors
Ann-Kathrin Schalkamp, Stefanie Lerche, Isabel Wurster, Benjamin Roeben, Milan Zimmermann, Franca Fries, Anna-Katharina von Thaler, Gerhard Eschweiler, Walter Maetzler, Daniela Berg, Fabian H Sinz, Kathrin Brockmann
Machine learning-based personalized composite score dissects risk and protective factors for cognitive and motor function in older participants
Journal of neurochemistry
Published

Circulating medium- and long-chain acylcarnitines are associated with plasma P-tau181 in cognitively normal older adults

Authors
Tahmida Sharmin, Pratishtha Chatterjee, James D Doecke, Nicholas J Ashton, Kevin Huynh, Steve Pedrini, Hamid R Sohrabi, Benjamin Heng, Shaun Eslick, Henrik Zetterberg, Kaj Blennow, Manohar Garg, Ralph N Martins
Circulating medium- and long-chain acylcarnitines are associated with plasma P-tau181 in cognitively normal older adults
Brain : a journal of neurology
Published

A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests

Authors
Noëlle Warmenhoven, Gemma Salvadó, Shorena Janelidze, Niklas Mattsson-Carlgren, Divya Bali, Anna Orduña Dolado, Hartmuth Kolb, Gallen Triana-Baltzer, Nicolas R Barthélemy, Suzanne E Schindler, Andrew J Aschenbrenner, Cyrus A Raji, Tammie L S Benzinger, John C Morris, Laura Ibanez, Jigyasha Timsina, Carlos Cruchaga, Randall J Bateman, Nicholas Ashton, Burak Arslan, Henrik Zetterberg, Kaj Blennow, Alexa Pichet Binette, Oskar Hansson
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests
Alzheimer's research & therapy
Published

Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adults

Authors
Jose Bernal, Inga Menze, Renat Yakupov, Oliver Peters, Julian Hellmann-Regen, Silka Dawn Freiesleben, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H Schott, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I Incesoy, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, Sebastian Sodenkamp, Annika Spottke, Anna Esser, Falk Lüsebrink, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler
Longitudinal evidence for a mutually reinforcing relationship between white matter hyperintensities and cortical thickness in cognitively unimpaired older adults
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Published

Neuronal plasma biomarkers in acute ischemic stroke

Authors
Julia K Gundersen, Fernando Gonzalez-Ortiz, Thomas Karikari, Bjørn-Eivind Kirsebom, Katrin Mertes, Henrik Zetterberg, Hlin Kvartsberg, Ole Morten Rønning, Berglind Gísladóttir, Kaj Blennow, Tormod Fladby
Neuronal plasma biomarkers in acute ischemic stroke
Neurology
Published

Prevalence and Clinical Implications of Hemosiderin Deposits in Recent Small Subcortical Infarcts

Authors
Yu-Yuan Xu, Francesca M Chappell, Maria Del C Valdés Hernández, Carmen Arteaga-Reyes, Una Clancy, Daniela Jaime Garcia, Stewart Wiseman, Michael S Stringer, Michael Thrippleton, Yajun Cheng, Junfang Zhang, Xiaodi Liu, Angela C C Jochems, Fergus Doubal, Joanna M Wardlaw, MSS3 Study Group
Prevalence and Clinical Implications of Hemosiderin Deposits in Recent Small Subcortical Infarcts
European journal of neurology
Published

Plasma phosphorylated tau181 outperforms [<sup>18</sup>F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease

Authors
Kely Monica Quispialaya, Joseph Therriault, Antonio Aliaga, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Thomas K Karikari, Andrea L Benedet, Nicholas J Ashton, Arthur C Macedo, Firoza Z Lussier, Jenna Stevenson, Yi-Ting Wang, Jaime Fernandez Arias, Ali Hosseini, Takashi Matsudaira, Bertrand Jean-Claude, Brian M Gilfix, Eduardo R Zimmer, Jean-Paul Soucy, Tharick A Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto, Alzheimer's Disease Neuroimaging Initiative
Plasma phosphorylated tau181 outperforms [<sup>18</sup>F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease
The Lancet regional health. Europe
Published

Fluid biomarkers in multiple sclerosis: from current to future applications

Authors
Massimiliano Di Filippo, Lorenzo Gaetani, Diego Centonze, Harald Hegen, Jens Kuhle, Charlotte E Teunissen, Mar Tintoré, Luisa M Villar, Eline A J Willemse, Henrik Zetterberg, Lucilla Parnetti
Fluid biomarkers in multiple sclerosis: from current to future applications
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Published

Type 1 spinal muscular atrophy treated with nusinersen in Norway, a five-year follow-up

Authors
Merete Wik-Klokk, Magnhild Rasmussen, Kristin Ørstavik, Henrik Zetterberg, Milada Hagen, Marie Elizabeth Holtebekk, Anette Ramm-Pettersen, Sean Wallace
Type 1 spinal muscular atrophy treated with nusinersen in Norway, a five-year follow-up