Weakening connections: new molecular mechanism discovered behind loss of synapses during neurodegenerative disease
A team of researchers led by Prof Kei Cho, Group Leader from UK DRI at King’s, has uncovered a new molecular mechanism behind the weakening of synapses and neuronal dysfunction in tauopathies. The findings, published in The Journal of Neuroscience, provide new insight into the cascade of pathological events initiated by harmful tau hyperphosphorylation, and point to possible new treatments for several neurodegenerative diseases.
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