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By joining the UK DRI you’ll belong to a team of fantastic researchers, technical specialists and professional support staff passionate about accelerating the discovery, development and delivery of interventions that will help diagnose, treat and ultimately prevent dementia, directly benefitting people affected by dementia, their carers, families and the community.

We’re looking for brilliant people with diverse perspectives. Together our unique contributions will transform the range and pace of research on dementia. You’ll be supported by the very best tools and resources and join a culture that encourages high risk/reward science and sharing of ideas.

We are a vibrant, ambitious and interactive community. We offer opportunities at all career levels for scientists and support staff in our seven centres across the UK, as well as in our London-based HQ team.

We’re always interested in hearing from people as passionate about our mission as we are. To find out more about working at the UK DRI or our current opportunities, please contact us at

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UK DRI at The University of Cambridge

From biological to physical sciences: working across disciplines to boost our understanding of the processes underlying the earliest stages of neurodegeneration and ageing.

  • Specialisms at Cambridge
  • Molecular and cellular biological approaches to understanding disease mechanisms
  • Proteostasis, translational control at the synapse, myelin/axon interactions in neuronal health and disease
  • Biomechanics of brain ageing and its role in disease processes and therapy
  • Inter-disciplinary science, including biophysics and chemistry
  • Read more about Cambridge

    The UK DRI at The University of Cambridge focuses on the mechanistic processes involved in the earliest stages of neurodegenerative disease to identify therapeutic targets with the greatest potential to prevent dementia. These processes include the spreading of misfolded tau protein, the cold shock protein response in the repair of synapses and autophagy as a protective cellular response, all of which are relevant to several different types of dementia.

    Led by Professor Giovanna Mallucci, the team uses cellular and molecular approaches to better characterise these important processes with a strong emphasis on identifying molecular targets that can be rapidly translated into new dementia treatments for those in the early stages.

    UK DRI at The University of Cambridge, embraces biological and physical sciences in the newly refurbished Island Research Building on the Cambridge Biomedical Campus.

Apply for latest jobs at Cambridge

  • Senior Research Associate, UK DRI at Cambridge - Klenerman Lab

    Applications are invited for a Senior Research Associate position at the UK Dementia Research Institute (UK DRI), at the University of Cambridge, Department of Clinical Neurosciences. The post is within a collaboration between the laboratories of Professor Sir David Klenerman at the UK DRI and Professor Maria Grazia Spillantini in the Department of Clinical Neurosciences. The project aims to study how protein homeostasis is disrupted in human derived IPSC neurons leading to the formation of increased numbers of tau aggregates and how aggregates spread from neuron to neuron by super-resolution imaging of the aggregates formed in and secreted by the neurons. Ref: ZE29745, Closing date: 28 January 2022

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RT @DementiasUK: Applications for DPUK's Spring Academy are now open! An all-new week-long series of lectures, presentations and guided tu…
17 Jan 2022 13:09

RT @cardiffuni: 4/7 Next up, Dame Ottoline met with Professor Julie Williams, the team at @UKDRI in Cardiff and our Pro Vice-Chancellor, Re…
17 Jan 2022 13:08