We're recruiting!
By joining the UK DRI you’ll belong to a team of fantastic researchers, technical specialists and professional support staff passionate about accelerating the discovery, development and delivery of interventions that will help diagnose, treat and ultimately prevent dementia, directly benefitting people affected by dementia, their carers, families and the community.
We’re looking for brilliant people with diverse perspectives. Together our unique contributions will transform the range and pace of research on dementia. You’ll be supported by the very best tools and resources and join a culture that encourages high risk/reward science and sharing of ideas.
We are a vibrant, ambitious and interactive community. We offer opportunities at all career levels for scientists and support staff in our eight centres across the UK, as well as in our London-based Core team.
We’re always interested in hearing from people as passionate about our mission as we are. To find out more about working at the UK DRI or our current opportunities, please contact us at enquiries@ukdri.ac.uk.
Featured jobs
Core team
Public Affairs Manager (Maternity Contract) - UK DRI Core team
We are looking for an energetic, proactive and skilled public affairs and communications professional to continue to help raise the political profile of the UK DRI through the delivery of an effective public affairs strategy. Deadline: 2 December 2024.
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Core team
UK DRI at The University of Cambridge
From biological to physical sciences: working across disciplines to boost our understanding of the processes underlying the earliest stages of neurodegeneration and ageing.
- Specialisms at Cambridge
- Molecular and cellular biological approaches to understanding disease mechanisms
- Proteostasis, translational control at the synapse, myelin/axon interactions in neuronal health and disease
- Biomechanics of brain ageing and its role in disease processes and therapy
- Inter-disciplinary science, including biophysics and chemistry
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Read more about Cambridge
The UK DRI at The University of Cambridge focuses on the mechanistic processes involved in the earliest stages of neurodegenerative disease to identify therapeutic targets with the greatest potential to prevent dementia. These processes include the spreading of misfolded tau protein, the cold shock protein response in the repair of synapses and autophagy as a protective cellular response, all of which are relevant to several different types of dementia.
The team uses cellular and molecular approaches to better characterise these important processes with a strong emphasis on identifying molecular targets that can be rapidly translated into new dementia treatments for those in the early stages.
UK DRI at The University of Cambridge, embraces biological and physical sciences in the newly refurbished Island Research Building on the Cambridge Biomedical Campus.
Apply for latest jobs at Cambridge
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Post-Doctoral Research Associate / Research Assistant (Fixed Term) UK DRI at Cambridge
About the role: The post will focus on the integration of novel PET and blood-based biomarkers of neuroinflammation, neuropathology and neurodegeneration, and clinical outcomes in models of disease progression in genetic and sporadic frontotemporal lobar degeneration. In this role, you will lead (i) PET imaging recruitment and data analysis in patients with frontotemporal dementia and progressive supranuclear palsy, (ii) the coordination of ON-FIRE and related studies on blood-based biomarkers. You will drive the project, develop and deliver the study's research objectives and be well equipped to present developments and key findings to relevant stakeholders. What we are looking for: For this post, you will have an undergraduate and/or a PhD in neurosciences, psychology, physiology or related discipline. You will have knowledge of neuroimaging, related research methods and applications, and project management skills. Experience in patient recruitment in research studies of dementia or mental health disorders would be advantageous. You will collaborate within a balanced team with post-doctoral scientists, clinical fellows, research nurses and students to ensure efficient research activities across the center. Reference No: ZE44012 Closing date: 08-12-2024
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Post-Doctoral Research Associate (Fixed Term) UK DRI at Cambridge
About the role: As a Post-Doctoral Research Associate, you will lead the statistical analysis and data management for multivariate biomarkers identified using novel biochemical assays including SIMOA, NULISA, Mass Spectrometry, multiomics and other data generating platforms. The role will involve computational analyses of blood-derived data - not wet-lab analyses on the samples - and leading academic and industry partners including biochemical laboratory facilities such as the Biomarker Factory at the Dementia Research Institute. The postholder will develop pipelines to (i) centralise adjunct data from all sites to Cambridge; (ii) combine multimodal data, linking blood samples to NHS digital records, genetics and available neuroimages; (iii) format and share data through the Dementias Platform UK data portal. You will lead computational analyses on biomarkers data, polygenic risk score calculations, and immunophenotyping data. You will drive the project, develop and deliver the study's research objectives and be well equipped to present developments and key findings to relevant stakeholders. What we are looking for: For this post, you will have an undergraduate and/or a PhD in Bioinformatics, Statistics or related discipline. You will have in-depth of knowledge of biostatistics, and related research methods and applications. Experience with machine learning algorithms and strong programming skills using platforms such as MATLAB, R, Bash and Python will be essential. Reference No: ZE44008 Closing date: 08-12-2024
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