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By joining the UK DRI you’ll belong to a team of fantastic researchers, technical specialists and professional support staff passionate about accelerating the discovery, development and delivery of interventions that will help diagnose, treat and ultimately prevent dementia, directly benefitting people affected by dementia, their carers, families and the community.

We’re looking for brilliant people with diverse perspectives. Together our unique contributions will transform the range and pace of research on dementia. You’ll be supported by the very best tools and resources and join a culture that encourages high risk/reward science and sharing of ideas.

We are a vibrant, ambitious and interactive community. We offer opportunities at all career levels for scientists and support staff in our seven centres across the UK, as well as in our London-based HQ team.

We’re always interested in hearing from people as passionate about our mission as we are. To find out more about working at the UK DRI or our current opportunities, please contact us at

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UK DRI at Imperial College London

From sleep to the microbiome: bringing new approaches and research tools to the study of dementia to discover new disease mechanisms and therapeutic targets.

  • Specialisms at Imperial College London
  • Neuroinflammation and neurodegeneration
  • Epigenomic influences on risks and progression of dementia
  • Roles of the microbiome in cognition and neurodegeneration
  • Circadian neurobiology and mechanisms of neurodegeneration
  • Neurotechnologies for targeted neuronal and glial modulation
  • Read more about Imperial College London

    UK DRI at Imperial College London has innovation as its theme. This draws on the university’s unique strengths and focus on science, engineering, medicine and business. Led by Professor Paul Matthews, the research team brings novel, cutting edge approaches and research tools to the study of dementia to discover new disease mechanisms and therapeutic targets. They will initially focus on the earliest pre-symptomatic stages of Alzheimer’s disease, addressing what determines the transition to neurodegeneration, but will investigate mechanisms that are likely shared across many of the dementias.

    With access to large, well characterised longitudinal cohorts the team will explore causes of individual variation in dementia within populations, looking at changes that occur across the lifespan and specifically addressing metabolic factors, the relationship with microorganisms in gut (the microbiome) and the role of sleep. The team will use a range of resources including Dementias Platform UK and the MRC-NIHR National Phenome Centre.

    UK DRI at Imperial College London will be located at the White City campus Hammersmith, London, in the Sir Michael Uren Biomedical Engineering Research Hub due to be completed in 2019, alongside Imperial’s translation and innovation ‘I-HUB’.

Apply for latest jobs at Imperial College London

  • Edmond and Lily Safra Research Fellow, UK DRI at Imperial

    UK DRI is seeking an Edmond and Lily Safra Research Fellow to join the department of Brain Sciences at Imperial College London. You will belong to a cohort of up to five Fellows recruited during the 2023-24 academic year. The Fellowships may be held for 3 years in the first instance. You may spend up to 12 months visiting other research institutions and/ or in industry, the maximum time spent at any one institution or company being 6 months. Research space will be provided at Imperial, consistent with needs, along with a non-renewable research start-up fund of £30,000. You will have access to specific additional support for specialised equipment that they might need. Additional funds may also be available on a project-by-project basis from other internal funds, including e.g., those of the NIHR Biomedical Research Centre or the UKRI Impact Acceleration Account (IAA) scheme administered by the College. You will lead and grow a scientific programme of the highest quality in Parkinson’s disease research towards international excellence in the chosen area, publish research papers in peer-reviewed journals, attend and present work at international conferences and obtain external research funding. For this role you have to have achieved a PhD or equivalent higher research degree in a relevant field, have previous research and publication record with evidence of potential for international excellence and leadership in the chosen area of science and you will now be building on existing post-doctoral or equivalent research training. Ref: MED03955, Closing date: 9 April 2024

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