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By joining the UK DRI you’ll belong to a team of fantastic researchers, technical specialists and professional support staff passionate about accelerating the discovery, development and delivery of interventions that will help diagnose, treat and ultimately prevent dementia, directly benefitting people affected by dementia, their carers, families and the community.

We’re looking for brilliant people with diverse perspectives. Together our unique contributions will transform the range and pace of research on dementia. You’ll be supported by the very best tools and resources and join a culture that encourages high risk/reward science and sharing of ideas.

We are a vibrant, ambitious and interactive community. We offer opportunities at all career levels for scientists and support staff in our seven centres across the UK, as well as in our London-based HQ team.

We’re always interested in hearing from people as passionate about our mission as we are. To find out more about working at the UK DRI or our current opportunities, please contact us at enquiries@ukdri.ac.uk.

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​UK DRI at UCL

Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test.

  • Specialisms at UCL
  • Mechanistic understanding of dysfunction in cells and neural systems
  • Gene expression and biological pathways in single cells related to the progression of Alzheimer’s disease
  • New biomarkers to monitor disease progression
  • Deficits in axonal transport in early neurodegeneration
  • Wnt signalling in synapses to discover new targets for future dementia therapies
  • Read more about UCL

    From lab bench to bedside, and back again

    UCL was selected as the hub of the UK DRI in 2016 because of its strength to bring together excellent clinical and basic neuroscience research to advance our understanding of neurodegeneration and identify novel targets and therapeutic approaches for dementia. As the hub, it has a larger research programme and also is the location for the national headquarters team who connect the whole institute together.

    Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test. The groups believe in intervening earlier in disease in order to change the trajectory.

    We need to better understand the diversity and complexity of neurodegenerative diseases, like Alzheimer's disease, in order to understand the mechanisms involved, and ultimately how we can alter them to improve people's lives.

    We must find treatments quicker, and that's why the UK DRI at UCL is taking a novel approach by integrating diverse expertise for efficiency, from genetics to diagnostics.

    This work is enhanced by incredible clinical resources. Researchers have access to unique clinical cohorts, where comprehensive data has been collected throughout disease progression including memory assessments and brain tissue. The UK DRI at UCL provides a clinical arm to the whole of the UK DRI.

    The future iconic home of the UK DRI at UCL will be alongside UCL's Queen Square Institute of Neurology in a new building on Gray's Inn Road.

    Visit the UK DRI at UCL local website for up-to-date news.

Apply for latest jobs at UCL

  • Research Technician, UK DRI at UCL - Fluid Biomarker Lab

    The UK DRI is seeking a Research Technician to join the Fluid Biomarker Lab in UCL. The UK DRI Fluid Biomarker Laboratory at UCL has recently set up a new Fluid Biomarker Platform in order to facilitate fluid biomarker research across the UK DRI national network. You will undertake the biomarker measurements for UK DRI projects that the new platform will facilitate. This will entail using a variety of state-of-the-art immunoassay platforms to perform biomarker measurements on fluid samples from collaborator labs. These projects may be small i.e., less than 500 samples, or very large i.e., 10,000+ samples. The results must then be curated and presented in a format that is accessible to our collaborators. You will have a BSc in a Biomedical subject or equivalent experience, and experience with immunoassays. General laboratory competence and an ability to use basic lab equipment, such as centrifuge / pipette is essential as are excellent organisational, interpersonal, and communication skills. An understanding of the UK DRI, an interest in its research work, and a commitment to supporting high quality research is also a requirement. Ref: B02-04844, Closing date: 04 April 2023

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