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Since launching in 2017, our institute has rapidly grown to over 350 researchers and 150 students, but we have space for many more as we grow the capacity in the field.

We’re looking for brilliant people who will help transform the range and pace of research on dementia. You’ll be supported by the very best tools and resources and join a culture that encourages high risk/reward science and sharing of ideas.

Together our teams create a vibrant, ambitious and interactive neuroscience community. We're seeking programme leaders, research associates, post-docs and other roles to fill our teams across our seven centres, as well as our operational headquarters team (based at UCL).

For recruitment enquiries, please contact us on enquiries@ukdri.ac.uk or 020 3108 6538.

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​UK DRI at UCL

Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test.

  • Specialisms at UCL
  • Mechanistic understanding of dysfunction in cells and neural systems
  • Gene expression and biological pathways in single cells related to the progression of Alzheimer’s disease
  • New biomarkers to monitor disease progression
  • Deficits in axonal transport in early neurodegeneration
  • Wnt signalling in synapses to discover new targets for future dementia therapies
  • Read more about UCL

    From lab bench to bedside, and back again 

    UCL was selected as the hub of the UK DRI in 2016 because of its strength to bring together excellent clinical and basic neuroscience research to advance our understanding of neurodegeneration and identify novel targets and therapeutic approaches for dementia. As the hub, it has a larger research programme and also is the location for the national headquarters team who connect the whole institute together.

    Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test. The groups believe in intervening earlier in disease in order to change the trajectory.

    We need to better understand the diversity and complexity of neurodegenerative diseases, like Alzheimer's disease, in order to understand the mechanisms involved, and ultimately how we can alter them to improve people's lives.

    We must find treatments quicker, and that's why the UK DRI at UCL is taking a novel approach by integrating diverse expertise for efficiency, from genetics to diagnostics.

    This work is enhanced by incredible clinical resources. Researchers have access to unique clinical cohorts, where comprehensive data has been collected throughout disease progression including memory assessments and brain tissue. The UK DRI at UCL provides a clinical arm to the whole of the UK DRI.

    The future iconic home of the UK DRI at UCL will be alongside UCL's Queen Square Institute of Neurology in a new building on Gray's Inn Road.

    Visit the UK DRI at UCL local website for up-to-date news.

Apply for latest jobs at UCL

  • Research Fellow (Organic Chemistry/Radiochemistry), UK DRI at UCL - Duff Lab

    The UK DRI at UCL is looking to appoint a highly motivated postdoctoral Research Fellow in organic chemistry/radiochemistry. The project is part of a collaboration between Professor Karen Duff, Director of the UK Dementia Research Institute at UCL, and Professor Erik Arstad, Director of the Centre for Radiopharmaceutical Chemistry (CRC), and will involve the development of a novel positron emission tomography (PET) tracer for imaging of dementia. The successful candidate will be required to synthesise small molecule target compounds, including precursors for radiolabelling, and will also have the opportunity to work with labelling chemistry for fluorine-18. Successful applicants must have a PhD in a relevant area, eg, organic chemistry, medicinal chemistry or radiochemistry, and expert knowledge and excellent practical skills in organic chemistry. Experience with radiochemistry, in particular fluorine-18 labelling chemistry, is desirable. Ref: 1862742, Closing date: 17 April

    Apply to centre

Group leaders

We have over 50 group leaders working across the institute, and are always seeking to fill more of these positions on a rolling basis - please contact your centre of interest to discuss opportunities further.

As a professor or fellow at one of the seven UK DRI centres, you would lead a group of postdoctoral fellows, PhD students and technical support staff. Directing activities on a local level and feeding into the organisation’s wider mission, you would provide the intellectual energy and independent thinking necessary to lead cutting-edge research, shaping the overall aims and achievements of your group.


To be successful, you should have a proven track record of internationally competitive scientific research and persuasive plans for a new and exciting UK DRI core programme. In return, the institute offers a five-year research programme package of up to £3 million for a professor and up to £1.5 million for a fellow. Recruiting UK DRI centres are offering competitive salaries. Programme leaders will be employees of the university hosting the UK DRI centre and will be employed under the standard employment terms and conditions of that university.

The UK DRI welcomes scientists from all disciplines. We encourage you to consider the specialisms across the institute and have a discussion with the associate director of your centre of interest. You will submit one application directly to your preferred UK DRI centre, which will be strongly considered at selection stage by the institute as a whole.

Group leader recruitment pack

Postdoctoral researchers, research assistants and technicians

Our UK DRI centres are filling positions within their programmes. The institute offers interdisciplinary training and cutting-edge resources, with innovation at its heart.

We continuously have opportunities at all levels. Please explore within each centre to see roles that are open to join our ambitious and interactive community.

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