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Since launching in 2017, our institute has rapidly grown to over 350 researchers and 150 students, but we have space for many more as we grow the capacity in the field.

We’re looking for brilliant people who will help transform the range and pace of research on dementia. You’ll be supported by the very best tools and resources and join a culture that encourages high risk/reward science and sharing of ideas.

Together our teams create a vibrant, ambitious and interactive neuroscience community. We're seeking programme leaders, research associates, post-docs and other roles to fill our teams across our seven centres, as well as our operational headquarters team (based at UCL).

For recruitment enquiries, please contact us on enquiries@ukdri.ac.uk or 020 3108 6859.

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​UK DRI at UCL

Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test.

  • Specialisms at UCL
  • Mechanistic understanding of dysfunction in cells and neural systems
  • Gene expression and biological pathways in single cells related to the progression of Alzheimer’s disease
  • New biomarkers to monitor disease progression
  • Deficits in axonal transport in early neurodegeneration
  • Wnt signalling in synapses to discover new targets for future dementia therapies
  • Read more about UCL

    From lab bench to bedside, and back again 

    UCL was selected as the hub of the UK DRI in 2016 because of its strength to bring together excellent clinical and basic neuroscience research to advance our understanding of neurodegeneration and identify novel targets and therapeutic approaches for dementia. As the hub, it has a larger research programme and also is the location for the national headquarters team who connect the whole institute together.

    Research at the UK DRI at UCL covers the journey from the person living with dementia to the laboratory and back again - with improved diagnosis and potential therapies put to the test. The groups believe in intervening earlier in disease in order to change the trajectory.

    We need to better understand the diversity and complexity of neurodegenerative diseases, like Alzheimer's disease, in order to understand the mechanisms involved, and ultimately how we can alter them to improve people's lives.

    We must find treatments quicker, and that's why the UK DRI at UCL is taking a novel approach by integrating diverse expertise for efficiency, from genetics to diagnostics.

    This work is enhanced by incredible clinical resources. Researchers have access to unique clinical cohorts, where comprehensive data has been collected throughout disease progression including memory assessments and brain tissue. The UK DRI at UCL provides a clinical arm to the whole of the UK DRI.

    The future iconic home of the UK DRI at UCL will be alongside UCL's Queen Square Institute of Neurology in a new building on Gray's Inn Road.

    Visit the UK DRI at UCL local website for up-to-date news.

Apply for latest jobs at UCL

  • Centre Research Administrator, UK DRI at UCL

    Applications are open for a Centre Research Administrator to support the UK DRI at UCL, one of seven centres of the UK Dementia Research Institute. You will work closely with the Centre Manager to provide a varied, efficient and effective support function to enable cutting-edge science into the neurodegenerative disorders that cause dementia. You’ll need to have experience of research grant administration or budget management coupled with an administrative background in Higher Education; experience of working in a research-intensive laboratory environment is very desirable. You’ll have great organisation and prioritisation skills, strong communication skills and a commitment to providing a responsive and helpful support function to colleagues in the centre. This is an exciting chance for an experienced administrator to directly facilitate critical research, helping embed a streamlined administrative function into the centre. Ref: 1833472, Closing date: 3 November

    Apply to centre
  • Research Fellow, UK DRI at UCL - De Strooper Lab

    The De Strooper lab, based in the UK DRI at UCL, is seeking an enthusiastic and motivated scientist to join the team and contribute towards the establishment of the lab in London. You will be responsible for the delivery of a high-quality research project investigating the cellular response that characterises Alzheimer’s disease, including designing and running experiments, recording results, analysing data and writing up the results. The role will involve significant collaboration with other scientists in the UK DRI, the ARUK UCL Drug Discovery Institute, and research groups at KULeuven and VIB institute in Belgium, and so travel, interaction and cross-communication will be a key element. This is a unique opportunity to use a variety of techniques, including single cell transcriptomics, molecular and cellular biology, imaging and functional approaches using human stem cells. You should have a PhD in life sciences or a cognate area coupled with expertise in tissue culture, cell biology and molecular biology; experience with iPS cells would be an advantage. Ref: 1824834, Closing date: 20 October

    Apply to centre
  • Research Fellow/Senior Research Fellow (x2) in Bioinformatics, UK DRI at UCL - De Strooper Lab

    This is an exciting opportunity for a motivated and ambitious bioinformatician to join the De Strooper Lab at the UK DRI in London. Bart De Strooper is an active and internationally acclaimed researcher with a large and productive laboratory programme currently divided between Leuven and London. His research focuses on understanding the fundamental mechanisms that underlie neurodegenerative disease with a particular interest in the cellular phase of Alzheimer’s disease, the neuro-immune axis and single cell genomics. Your project aims to understand early cellular changes happening during the onset of Alzheimer's disease using techniques such as single cell transcriptomics or proteomics. Collaboration is key, and your project will be an integral part of a larger initiative to work towards a complete spatial and temporal cellular atlas of Alzheimer's disease. Candidates will hold a PhD in bioinformatics or a cognate area or have submitted your thesis prior to starting in post. You’ll have good knowledge of machine learning and experience of high-performance computing (including software development, Python etc), database management and analysis of high-throughput data. You’ll enjoy working collaboratively with colleagues in a multidisciplinary setting and be passionate about the mission and research work of the UK DRI. To be appointed at the more senior level you’ll have demonstrable experience of leading projects and supervising staff or students. Ref: 1824734, Closing date: 20 Oct

    Apply to centre
  • UK DRI Group Leader (Senior/Principal Fellow) in dementia and neurodegeneration at UCL

    The UK DRI at UCL are looking to appoint a new Group Leader (Senior/Principal Fellow), who will lead an internationally competitive research programme, relevant to the area of neurodegeneration, with the ultimate aim of improving human health. You will receive extensive support from the UK DRI, including up to £1.5 million start-up funding over a five-year period, appointment based on the MRC tenure-track route, access to shared equipment and technology across a national institute and membership of a community of world-leading scientists. You are also entitled to the full range of UCL staff benefits and development opportunities. You will have substantial postdoctoral experience, a proven track record of internationally competitive scientific research relevant to the UK DRI and a commitment to, appreciation and understanding of the mission of the UK DRI. You’ll be experienced in planning and developing projects or programmes of research and have a wide knowledge of techniques and methodologies related to research in neurodegeneration. You’ll propose an exciting and innovative programme of research that demonstrably interfaces and compliments the UK DRI’s current portfolio and science strategy, and evidence that you have the potential to lead, inspire and develop a research group into an excellent team. Rolling deadline.

    Apply to centre

Group leaders

We have over 50 group leaders working across the institute, and are always seeking to fill more of these positions on a rolling basis - please contact your centre of interest to discuss opportunities further.

As a professor or fellow at one of the seven UK DRI centres, you would lead a group of postdoctoral fellows, PhD students and technical support staff. Directing activities on a local level and feeding into the organisation’s wider mission, you would provide the intellectual energy and independent thinking necessary to lead cutting-edge research, shaping the overall aims and achievements of your group.


To be successful, you should have a proven track record of internationally competitive scientific research and persuasive plans for a new and exciting UK DRI core programme. In return, the institute offers a five-year research programme package of up to £3 million for a professor and up to £1.5 million for a fellow. Recruiting UK DRI centres are offering competitive salaries. Programme leaders will be employees of the university hosting the UK DRI centre and will be employed under the standard employment terms and conditions of that university.

The UK DRI welcomes scientists from all disciplines. We encourage you to consider the specialisms across the institute and have a discussion with the associate director of your centre of interest. You will submit one application directly to your preferred UK DRI centre, which will be strongly considered at selection stage by the institute as a whole.

Group leader recruitment pack

Postdoctoral researchers, research assistants and technicians

Our UK DRI centres are filling positions within their programmes. The institute offers interdisciplinary training and cutting-edge resources, with innovation at its heart.

We continuously have opportunities at all levels. Please explore within each centre to see roles that are open to join our ambitious and interactive community.

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Latest tweets from @UKDRI

RT @inna_slutsky: You are welcome to come to discuss new insights on stability and instability of neural circuits! New theoretical aspects…
18 Oct 2019 12:36

Wishing all the UK researchers travelling to #SfN19 a very safe journey and enjoyable conference! Don't miss Dr… https://t.co/XrVBO3s4b7
18 Oct 2019 12:02