Abstract
Trends Neurosci. 2024 Sep 4:S0166-2236(24)00169-3. doi: 10.1016/j.tins.2024.08.014. Online ahead of print.
ABSTRACT
Neuroinflammation is a feature of both neurodegenerative disease and normal brain aging. The roles of type I interferon (IFN-I) in the aged brain are incompletely understood. A recent article by Roy et al. reveals pervasive IFN-I activity in normal mouse brain aging, and highlights the importance of microglial IFN-I signaling in neuroinflammation.
PMID:39237428 | DOI:10.1016/j.tins.2024.08.014