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Neurology
Published

Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration.

Authors

Philip S J Weston, Teresa Poole, Natalie S Ryan, Akshay Nair, Yuying Liang, Kirsty Macpherson, Ronald Druyeh, Ian B Malone, R Laila Ahsan, Hugh Pemberton, Jana Klimova, Simon Mead, Kaj Blennow, Martin N Rossor, Jonathan M Schott, Henrik Zetterberg, Nick C Fox

Abstract

To investigate whether serum neurofilament light (NfL) concentration is increased in familial Alzheimer disease (FAD), both pre and post symptom onset, and whether it is associated with markers of disease stage and severity.

PMID:29070659 | DOI:

UK DRI Authors

Profile picture of Henrik Zetterberg

Prof Henrik Zetterberg

Group Leader

Pioneering the development of fluid biomarkers for dementia

Prof Henrik Zetterberg