UK DRI at Cardiff University has been officially opened by Health Secretary Vaughan Gething.
More than 70 scientists from around the world have been recruited to the centre with the aim of expanding the group to 100 in the near future.
All of our six centres work together and bring different specialisms to the institute. UK DRI at Cardiff will build upon research strengths in dementia genetics; immunology; computational analytics; cellular and whole system modelling; and neuroimaging to identify disease mechanisms and therapies for a range of dementias including Alzheimer’s disease.
In recent years, more than 40 genes which contribute to the risk of Alzheimer’s disease have been discovered and the team at Cardiff will use that knowledge to work on new theories and discoveries.
Focusing on clear evidence that indicates answers can be found within the brain’s immune system, they will work on several separate but aligned research programmes that will model Alzheimer’s disease in various ways, including through stem cells which can be transformed into neurons, immune and other cells. They will even be able to combine these cells to create mini brains or organoids (3D cell cultures that incorporate some of the key features of an organ).