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Soyon Hong

Dr Soyon Hong

Group Leader

Dissecting pathways by which microglia contribute to region-specific synapse dysfunction in neurodegeneration

Biography

Dr Soyon Hong received her PhD in Neuroscience in 2012 from Harvard University and completed her post-doctoral fellowship at Boston Children’s Hospital and Harvard Medical School in 2018. While in this latter role, she conducted a study that was among the first to propose microglia as critical players in synaptic pathology in disease. She now brings these expertise and knowledge to establish a new UK DRI lab group at UCL.

Statement on teaching and mentorship

"I have mentored and taught many students and technicians through lectures and laboratory settings (26 mentees in laboratory settings to date). I highly value the opportunities to mentor. It is one aspect of my career that I find truly rewarding. I believe that having a positive, stimulating environment where trainees are valued is key to having a productive and creative lab. Trainees who join my laboratory will be trained in cellular and molecular biology including neuroscience and neuroimmunology. Moreover, they will be mentored to be independent critical thinkers, a core of my teaching philosophy."

News

Key publications

Nature neuroscience
Published
Author Correction: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease
Authors
Sebastiaan De Schepper, Judy Z Ge, Annerieke Sierksma, Gerard Crowley, Laís S S Ferreira, Dylan Garceau, Christina E Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, Soyon Hong
Author Correction: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease
Nature
Published
Intestinal macrophages modulate synucleinopathy along the gut-brain axis
Authors
Sebastiaan De Schepper, Viktoras Konstantellos, James A Conway, Dimitra Sokolova, Ludovica Zaccagnini, Matthew V Cowley, Annerieke Sierksma, Maria Yudina, Marisa Edmonds, Daria Gavriouchkina, Bethany Geary, Amber Wallis, Meral Celikag, Zeynep Baykam, Mónica Vara-Pérez, Gerard Crowley, Fabian Tobias Hager, Mitchell Bijnen, David Posner, Kelvin Luk, Vuk Cerovic, Menna Clatworthy, Elizabeth J Videlock, Zane Jaunmuktane, Kiavash Movahedi, Melanie Greter, Benny Chain, Dario R Alessi, Soyon Hong, Tim Bartels
Intestinal macrophages modulate synucleinopathy along the gut-brain axis
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference
Authors
Courtney M Kloske, Simin Mahinrad, Christopher J Barnum, Andre F Batista, Elizabeth M Bradshaw, Brittany Butts, Maria C Carrillo, Paramita Chakrabarty, Xiaoying Chen, Suzanne Craft, Sandro Da Mesquita, Luke C Dabin, Davangere Devanand, Violeta Duran-Laforet, Wassim Elyaman, Elizabeth E Evans, Patricia Fitzgerald-Bocarsly, Kate E Foley, Ashley S Harms, Michael T Heneka, Soyon Hong, Yu-Wen A Huang, Stephanie Jackvony, Laijun Lai, Yann Le Guen, Cynthia A Lemere, Shane A Liddelow, Alfonso Martin-Peña, Anna G Orr, Francisco J Quintana, Grace D Ramey, Jessica E Rexach, Stacey J S Rizzo, Claire Sexton, Alice S Tang, Jose G Torrellas, Andy P Tsai, Lynn van Olst, Keenan A Walker, Whitney Wharton, Malú Gámez Tansey, Donna M Wilcock
Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference

Hong Lab

Explore the work of the Hong Lab, working to understand immune mechanisms of neural circuitry and function

Three-dimensional reconstruction of perivascular macrophages