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MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU)

About the MRC PPU

The MRC PPU is a world class research institute led by Director, and UK DRI Associate Member, Prof Dario Alessi, in which researchers make use of cutting-edge technology and biochemistry to study cellular and molecular mechanisms that underpin a number of diseases such as neurological disorders, cancer and hypertension. 

The unit receives core funding from the Medical Research Council, allowing it to tackle major long-term questions, with a focus on the regulation of eukaryotic cell biology and human disease by protein phosphorylation and ubiquitylation. 

The MRC PPU operates as a focal point between leading life scientists, pharmaceutical companies and clinicians. Its aim is to make a critical contribution to biomedical research, leading to a deeper understanding of diseases and how to treat them.

Working with UK DRI

In 2020, we embarked on a collaboration with MRC PPU to advance proteomics capabilities in dementia research, providing matching funds for cutting-edge technology at the unit. Over the coming years, we will work together to better understand how proteins are impacted in neurodegenerative disease.