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PLoS One
Published

Abnormal brain white matter microstructure is associated with both pre-hypertension and hypertension.

Authors

Hideaki Suzuki, He Gao, Wenjia Bai, Evangelos Evangelou, Ben Glocker, Declan P O'Regan, Paul Elliott, Paul M Matthews

Abstract

To characterize effects of chronically elevated blood pressure on the brain, we tested for brain white matter microstructural differences associated with normotension, pre-hypertension and hypertension in recently available brain magnetic resonance imaging data from 4659 participants without known neurological or psychiatric disease (62.3±7.4 yrs, 47.0% male) in UK Biobank.

PMID:29145428 | DOI:10.1371/journal.pone.0187600

UK DRI Authors

Paul Elliott

Prof Paul Elliott

Group Leader

Using advanced methods in genetic, epidemiology and metabolic phenotyping to improve understanding of dementias

Prof Paul Elliott