Sleep
Published

Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: association with more slow waves and daytime sleepiness.

Authors

Vincenzo Muto, Ekaterina Koshmanova, Pouya Ghaemmaghami, Mathieu Jaspar, Christelle Meyer, Mahmoud Elansary, Maxime Van Egroo, Daphne Chylinski, Christian Berthomier, Marie Brandewinder, Charlotte Mouraux, Christina Schmidt, Grégory Hammad, Wouter Coppieters, Naima Ahariz, Christian Degueldre, André Luxen, Eric Salmon, Christophe Phillips, Simon N Archer, Loic Yengo, Enda Byrne, Fabienne Collette, Michel Georges, Derk-Jan Dijk, Pierre Maquet, Peter M Visscher, Gilles Vandewalle
Read More

Abstract

Sleep disturbances and genetic variants have been identified as risk factors for Alzheimer's disease (AD). Our goal was to assess whether genome-wide polygenic risk scores (PRS) for AD associate with sleep phenotypes in young adults, decades before typical AD symptom onset.

PMID:32671396 | DOI:10.1093/sleep/zsaa137

UK DRI Authors

Derk-Jan Dijk

Prof Derk-Jan Dijk

Group Leader

Developing and evaluating new technologies that can measure a person’s sleep and wake patterns at home

Prof Derk-Jan Dijk