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Aitana Sogorb-Esteve profile

Dr Aitana Sogorb-Esteve

(PhD (she/her))

Former Emerging Leader

Biography

Dr Aitana Sogorb-Esteve was a UK DRI Emerging Leader with a prestigious Race Against Dementia (RAD) Fellowship - jointly sponsored by Prof Jonathan Rohrer (Dementia Research Centre, UCL) and Group Leader Prof Henrik Zetterberg (UK DRI at UCL). 

Dr Sogorb-Esteve completed a degree in biology at the University of Alicante, her hometown in Spain; followed by a master and a PhD in neuroscience at the University Miguel Hernandez de Elche (Spain). 

She worked at the UK DRI at UCL from 2018 where she firstly focused on the study of novel fluid biomarkers for Alzheimer’s Disease, such as those related to pathology or neuroinflammation. Since 2020, Dr Sogorb-Esteve has worked as a postdoctoral researcher in Prof Jonathan Rohrer's lab at the Dementia Research Centre at UCL studying fluid biomarkers in Frontotemporal Dementia (FTD) as part of the Genetic FTD Initiative (GENFI). In 2021, Aitana was awarded the RAD Fellowship and started this project at the beginning of 2022, where Dr Sogorb-Esteve is working to identify biomarkers to assess synaptic dysfunction in FTD, with the aim of developing a method to measure these synaptic markers in blood samples and improve diagnostics for the disease.

In December 2025, Aitana joined The Center for Research in Neurological Diseases (CIEN) as Head of the Biomarkers, Biochemistry and Molecular Genetics Laboratory Platform, as well as Principal Investigator of a research group at the Alzheimer Center Fundación Reina Sofía – CIEN.

News

Key publications

Brain : a journal of neurology
Published
Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration
Authors
Julie F H De Houwer, Elise G Dopper, Renee van Buuren, Marijke Stokkel, Liset de Boer, Tine Swartenbroekx, Pam A Boesjes, Ana Rajicic, Aitana Sogorb-Esteve, Arabella Bouzigues, Lucy L Russell, Phoebe H Foster, Eve Ferry-Bolder, John C van Swieten, Lize C Jiskoot, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tiraboschi, Isabel Santana, Alexander Gerhard, Johannes Levin, Benedetta Nacmias, Markus Otto, Maxime Bertoux, Thibaud Lebouvier, Simon Ducharme, Chris R Butler, Isabelle Le Ber, Elizabeth Finger, Maria Carmela Tartaglia, Mario Masellis, James B Rowe, Matthis Synofzik, Fermin Moreno, Barbara Borroni, Henrik Zetterberg, Jonathan D Rohrer, Betty M Tijms, Yolande A L Pijnenburg, Charlotte Teunissen, Harro Seelaar
Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration
Alzheimer's research & therapy
Published
Longitudinal biomarker studies in human neuroimaging: capturing biological change of Alzheimer's pathology
Authors
Larissa Fischer, Dana Parker, Samira Maboudian, Corrina Fonseca, Claudia Tato-Fernández, Lucie Annen, Prithvi Arunachalam, Julia R Bacci, Michelle Barboure, Serena Capelli, Stamatia Karagianni, Lyduine E Collij, Paul Edison, Nick C Fox, Nicolai Franzmeier, Michel J Grothe, William J Jagust, Anne Maass, Maura Malpetti, Ross W Paterson, Aitana Sogorb-Esteve, Michael Schöll
Longitudinal biomarker studies in human neuroimaging: capturing biological change of Alzheimer's pathology
Brain : a journal of neurology
Published
Disease-modifying effects of TMEM106B in genetic frontotemporal dementia: a longitudinal GENFI study
Authors
Saira S Mirza, Maurice Pasternak, Andrew D Paterson, Ekaterina Rogaeva, Maria C Tartaglia, Sara B Mitchell, Sandra E Black, Morris Freedman, David Tang-Wai, Arabella Bouzigues, Lucy L Russell, Phoebe H Foster, Eve Ferry-Bolder, Martina Bocchetta, David M Cash, Henrik Zetterberg, Aitana Sogorb-Esteve, John van Swieten, Lize C Jiskoot, Harro Seelaar, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tiraboschi, Isabel Santana, Alexander Gerhard, Johannes Levin, Sandro Sorbi, Markus Otto, Florence Pasquier, Simon Ducharme, Chris Butler, Isabelle Le Ber, Elizabeth Finger, James B Rowe, Matthis Synofzik, Fermin Moreno, Barbara Borroni, Jonathan D Rohrer, Mario Masellis, GENetic Frontotemporal dementia Initiative (GENFI)
Disease-modifying effects of TMEM106B in genetic frontotemporal dementia: a longitudinal GENFI study
Science translational medicine
Published
Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes
Authors
Aitana Sogorb-Esteve, Sophia Weiner, Joel Simrén, Imogen J Swift, Martina Bocchetta, Emily G Todd, David M Cash, Arabella Bouzigues, Lucy L Russell, Phoebe H Foster, Eve Ferry-Bolder, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tiraboschi, Isabel Santana, Alexander Gerhard, Johannes Levin, Sandro Sorbi, Markus Otto, Florence Pasquier, Simon Ducharme, Chris R Butler, Isabelle Le Ber, Elizabeth Finger, Maria Carmela Tartaglia, Mario Masellis, James B Rowe, Matthis Synofzik, Fermin Moreno, Barbara Borroni, None Genfi, Kaj Blennow, Henrik Zetterberg, Jonathan D Rohrer, Johan Gobom, GENFI
Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes