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Bart De Strooper

Prof Bart De Strooper

Group Leader

Investigating the cellular reaction to amyloid beta and tau protein in Alzheimer's disease

Biography

Prof Bart De Strooper is a world-renowned Alzheimer's disease researcher, formerly based at the KU Leuven in Belgium, and was the founding Institute Director for the UK DRI (2017- 2023). 

He was Director at the Vlaams Instituut voor Biotechnologie and led a neuroscience department of over 250 researchers. He was elected to the Academy of Medical Sciences Fellowship in 2020, and has received several awards including the Potamkin prize, the Metlife Foundation Award for Medical Research, Alois Alzheimer’s prize, the highly prestigious Brain Prize 2018 and Commander in the Order of Leopold I. 

Prof De Strooper's research group at the UK DRI at UCL interrogates the fundamental mechanisms underlying Alzheimer’s and Parkinson’s disease.

News

Key publications

Nature communications
Published
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease
Authors
Kitty B Murphy, Di Hu, Leen Wolfs, Susan K Rohde, Gonzalo Leguía Fauró, Ivana Geric, Renzo Mancuso, Bart De Strooper, Sarah J Marzi
The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia xenografted into a mouse model of Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
Authors
Emre Fertan, Jeff Y L Lam, Giulia Albertini, Maarten Dewilde, Yunzhao Wu, Oluwatomi E S Akingbade, Dorothea Böken, Elizabeth A English, Bart De Strooper, David Klenerman
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Basic Science and Pathogenesis
Authors
Sebastiaan Moonen, Marta J Koper, Alicja Ronisz, Simona Ospitalieri, Zsuzsanna Vegh, Dries T'Syen, Sabine Rabe, Matthias Staufenbiel, Bart De Strooper, Sriram Balusu, Dietmar Rudolf Thal
Basic Science and Pathogenesis

De Strooper Lab

Explore the work of the De Strooper Lab Investigating the cellular reaction to amyloid beta and tau protein in Alzheimer's disease