Prof Bart De Strooper

Biography

Prof Bart De Strooper is a world-renowned Alzheimer's disease researcher, formerly based at the KU Leuven in Belgium, and was the founding Institute Director for the UK DRI (2017- 2023).

He was Director at the Vlaams Instituut voor Biotechnologie and led a neuroscience department of over 250 researchers. He was elected to the Academy of Medical Sciences Fellowship in 2020, and has received several awards including the Potamkin prize, the Metlife Foundation Award for Medical Research, Alois Alzheimer’s prize, the highly prestigious Brain Prize 2018 and Commander in the Order of Leopold I.

Prof De Strooper's research group at the UK DRI at UCL interrogates the fundamental mechanisms underlying Alzheimer’s and Parkinson’s disease.

News

Jan 29, 2024 - Research

Evidence grows for transmissible amyloid beta, but should we be concerned?

A new study from Dr Gargi Banerjee, Prof John Collinge and colleagues at the UCL...

Learn more Evidence grows for transmissible amyloid beta, but should we be concerned?

Jan 02, 2024 - Update

Introducing Julija Krupic, UK DRI at UCL: Understanding the earliest brain changes in Alzheimer’s

Dr Julija Krupic is the UK DRI at UCL’s newest Group Leader. A physicist by...

Learn more Introducing Julija Krupic, UK DRI at UCL: Understanding the earliest brain changes in Alzheimer’s

Key publications

Cell Stem Cell

Published Oct 07, 2021

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.

Authors

Hannah Walgrave, Sriram Balusu, Sarah Snoeck, Elke Vanden Eynden, Katleen Craessaerts, Nicky Thrupp, Leen Wolfs, Katrien Horré, Yannick Fourne, Alicja Ronisz, Edina Silajdžić, Amber Penning, Giorgia Tosoni, Zsuzsanna Callaerts-Vegh, Rudi D'Hooge, Dietmar Rudolf Thal, Henrik Zetterberg, Sandrine Thuret, Mark Fiers, Carlo Sala Frigerio, Bart De Strooper, Evgenia Salta

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.

Nat Commun

Published Jul 23, 2021

Identifying individuals with high risk of Alzheimer's disease using polygenic risk scores.

Authors

Ganna Leonenko, Emily Baker, Joshua Stevenson-Hoare, Annerieke Sierksma, Mark Fiers, Julie Williams, Bart de Strooper, Valentina Escott-Price

Identifying individuals with high risk of Alzheimer's disease using polygenic risk scores.

Nat Neurosci

Published Feb 15, 2021

Reactive astrocyte nomenclature, definitions, and future directions.

Authors

Carole Escartin, Elena Galea, András Lakatos, James P O'Callaghan, Gabor C Petzold, Alberto Serrano-Pozo, Christian Steinhäuser, Andrea Volterra, Giorgio Carmignoto, Amit Agarwal, Nicola J Allen, Alfonso Araque, Luis Barbeito, Ari Barzilai, Dwight E Bergles, Gilles Bonvento, Arthur M Butt, Wei-Ting Chen, Martine Cohen-Salmon, Colm Cunningham, Benjamin Deneen, Bart De Strooper, Blanca Díaz-Castro, Cinthia Farina, Marc Freeman, Vittorio Gallo, James E Goldman, Steven A Goldman, Magdalena Götz, Antonia Gutiérrez, Philip G Haydon, Dieter H Heiland, Elly M Hol, Matthew G Holt, Masamitsu Iino, Ksenia V Kastanenka, Helmut Kettenmann, Baljit S Khakh, Schuichi Koizumi, C Justin Lee, Shane A Liddelow, Brian A MacVicar, Pierre Magistretti, Albee Messing, Anusha Mishra, Anna V Molofsky, Keith K Murai, Christopher M Norris, Seiji Okada, Stéphane H R Oliet, João F Oliveira, Aude Panatier, Vladimir Parpura, Marcela Pekna, Milos Pekny, Luc Pellerin, Gertrudis Perea, Beatriz G Pérez-Nievas, Frank W Pfrieger, Kira E Poskanzer, Francisco J Quintana, Richard M Ransohoff, Miriam Riquelme-Perez, Stefanie Robel, Christine R Rose, Jeffrey D Rothstein, Nathalie Rouach, David H Rowitch, Alexey Semyanov, Swetlana Sirko, Harald Sontheimer, Raymond A Swanson, Javier Vitorica, Ina-Beate Wanner, Levi B Wood, Jiaqian Wu, Binhai Zheng, Eduardo R Zimmer, Robert Zorec, Michael V Sofroniew, Alexei Verkhratsky

Reactive astrocyte nomenclature, definitions, and future directions.

Lancet Neurol

Published Oct 30, 2020

Potential human transmission of amyloid β pathology: surveillance and risks.

Authors

Elsa Lauwers, Giovanna Lalli, Sebastian Brandner, John Collinge, Veerle Compernolle, Charles Duyckaerts, Gustaf Edgren, Stéphane Haïk, John Hardy, Adel Helmy, Adrian J Ivinson, Zane Jaunmuktane, Mathias Jucker, Richard Knight, Robin Lemmens, I-Chun Lin, Seth Love, Simon Mead, V Hugh Perry, James Pickett, Guy Poppy, Sheena E Radford, Frederic Rousseau, Carol Routledge, Giampietro Schiavo, Joost Schymkowitz, Dennis J Selkoe, Colin Smith, Dietmar R Thal, Tom Theys, Pierre Tiberghien, Peter van den Burg, Philippe Vandekerckhove, Clare Walton, Hans L Zaaijer, Henrik Zetterberg, Bart De Strooper

Potential human transmission of amyloid β pathology: surveillance and risks.