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Joanna Wardlaw

Prof Joanna Wardlaw

(CBE, MB ChB (Hons), MD, FRCR, FRCP, FMedSci, FRSE (she/her))

Group Leader and Clinical Director of the CVDR

Discovering how small vessel disease damages the brain and what we can do to prevent or treat it

Techniques

Advanced microscopy & imaging, Drug screening, Experimental medicine, Fluid biomarkers, Human brain imaging, Lipidomics, Mass spec-based proteomics, Metabolomics, Mouse behaviour, Mouse in vivo imaging, Single cell / nucleus transcriptomics, Software development, Statistical modelling, Viral-mediated expression

Biography

Prof Joanna Wardlaw, CBE, MB ChB (Hons), MD, FRCR, FRCP, FMedSci, FRSE, is Professor of Applied Neuroimaging at the University of Edinburgh, Foundation Chair of the UK DRI at Edinburgh, Director of the Row Fogo Centre for Research into Ageing and the Brain, and Consultant Neuroradiologist for NHS Lothian. Her work focuses on understanding the brain and its blood supply, and treatments to improve blood flow to the brain, including thrombolytic drugs that are now in routine use to treat stroke, and more recently treatments for small vessel disease and vascular dementia. Working with many colleagues, she has been instrumental in advancing understanding of the causes of cerebral small vessel disease and is now testing treatments in clinical trials. She has set up national research imaging facilities, co-ordinated international research networks, advanced stroke care worldwide and published over 1000 papers. A Fellow of the Royal Society of Edinburgh and the UK Academy of Medical Sciences, she has received awards from many UK and international brain and heart organisations, and was made a Commander of the Order of the British Empire (CBE) for services to Medicine and Neuroscience in 2016.

News

Key publications

International journal of stroke : official journal of the International Stroke Society
Published
Intravenous thrombolysis in patients with acute ischemic stroke and cerebral microbleeds: results from the ENCHANTED trial
Authors
Zien Zhou, Yilun Ge, Sohei Yoshimura, Takako Torii-Yoshimura, Yuki Sakamoto, Xiaoqiu Liu, Cheryl Carcel, Xiaoying Chen, Leibo Liu, Mark Parsons, Grant Mair, Richard Lindley, Joanna Wardlaw, Anderson Craig, Candice Delcourt
Intravenous thrombolysis in patients with acute ischemic stroke and cerebral microbleeds: results from the ENCHANTED trial
European stroke journal
Published
Randomised, controlled Trial of CT perfusion and angiography compared to CT alone in thrombolysis-eligible acute ischaemic stroke patients: The penumbra and recanalisation acute computed tomography in ischaemic stroke evaluation (PRACTISE) trial
Authors
Keith W Muir, Salwa El Tawil, Alex McConnachie, Ian Ford, Grant Mair, Jattinder Khaira, Kausik Chatterjee, Laszlo Sztriha, Omid Halse, Ibrahim Balogun, Sanjeev Nayak, Phil White, Elizabeth A Warburton, Joanna Wardlaw
Randomised, controlled Trial of CT perfusion and angiography compared to CT alone in thrombolysis-eligible acute ischaemic stroke patients: The penumbra and recanalisation acute computed tomography in ischaemic stroke evaluation (PRACTISE) trial
Nature communications
Published
Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI
Authors
Anna E Fürtjes, Isabelle F Foote, Charley Xia, Gail Davies, Joanna Moodie, Adele Taylor, David C Liewald, Paul Redmond, Janie Corley, Andrew M McIntosh, Heather C Whalley, Susana Muñoz Maniega, Maria Valdés Hernández, Ellen Backhouse, Karen Ferguson, Mark E Bastin, Joanna Wardlaw, Javier de la Fuente, Andrew D Grotzinger, Michelle Luciano, W David Hill, Ian J Deary, Elliot M Tucker-Drob, Simon R Cox
Measurement characteristics and genome-wide correlates of lifetime brain atrophy estimated from a single MRI
BMJ open
Published
Carbon footprint of a sample of clinical trials for people with neurological disorders: cross-sectional analysis
Authors
Denise Cranley, Sarah Dunn, John-Paul Taylor, Michael Jr Desborough, Jennifer Craig, Nikola Sprigg, Rachel McComish, Thomas Foltynie, Joanna Wardlaw, Katherine Oatey, Anna Heye, Philip Bath, Karen Innes, Lynn Dinsmore, Jessica Griffiths, Lisa Fox, Paula R Williamson, Rustam Al-Shahi Salman
Carbon footprint of a sample of clinical trials for people with neurological disorders: cross-sectional analysis

Wardlaw lab

Explore the work of the Wardlaw lab focused on understanding how small vessel disease damages the brain and what we can do to prevent and treat it.

Superintendent Radiographer Charlotte Jardine and colleague examines brain scans on a computer screen