"We aim to reveal how entorhinal-hippocampal neuron-glia networks change during Alzheimer's disease and find effective methods to intervene with these changes." Julija Krupic
UK DRI Group Leader
Dr Krupic earned her undergraduate degree in Physics at Vilnius University, followed by a Master's in Bioimaging sciences at Imperial College London where she started to apply physics to biological problems working on cerebellar Purkinje cells. She then completed her PhD in Neuroscience at UCL in Prof John O’Keefe’s group, working on the medial entorhinal grid cells. Her work showed that hexagonal grid cell symmetry fundamentally depends on the geometry of the enclosures. After her PhD, she was awarded a Sir Henry Wellcome postdoctoral fellowship and moved to the Salk Institute to develop techniques for in vivo single-cell tracing in the hippocampus and entorhinal cortex. From Salk, she moved to the University of Cambridge to start her group as a Sir Henry Dale fellow, where she continued to study the basic mechanisms of entorhinal-hippocampal neural circuits and how they generate allocentric spatial maps. At the UK DRI at UCL, Dr Krupic will use her expertise in basic science to infer the early mechanisms of entorhinal-hippocampal neuron-glia circuit impairments in Alzheimer’s disease.
1. Lab website
2. Team Members
Dr Pauline Kerekes (Postdoctoral Researcher)
Hinze Ho (Research Assistant)
Marino Krstulovic (Research Assistant)