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Maura Malpetti profile

Dr Maura Malpetti

Emerging Leader

Using specialist brain scans and novel blood tests to measure inflammation and accelerate the development of new treatments

Techniques

Bioinformatics, Flow cytometry, Fluid biomarkers, Human brain imaging, Statistical modelling

Biography

Dr Maura Malpetti is a Race Against Dementia Alzheimer’s Research UK Fellow and a Senior Research Associate in the Department of Clinical Neurosciences at the University of Cambridge. She originally trained in Italy for her BSc and MSc, and obtained her PhD in Clinical Neurosciences at the University of Cambridge. She further trained as a visiting researcher at the University of California San Francisco, and the Ludwig Maximilian University of Munich. Her research focusses on in vivo biomarkers for inflammation, tau and synaptic loss to investigate the pathophysiology of primary tauopathies, frontotemporal dementia, and related disorders. To this end, her lab integrates PET imaging and clinical data with fluid markers and post-mortem pathology to identify and validate early diagnostic and prognostic markers that can inform the design of new disease-modifying treatment strategies

News

Key publications

Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Biomarkers
Authors
Colin Groot, Emma M Coomans, Christopher C Rowe, Vincent Dore, Azadeh Feizpour, Elsmarieke van de Giessen, Wiesje M van der Flier, Yolande A L Pijnenburg, Pieter Jelle Visser, Anouk den Braber, Michael J Pontecorvo, Samantha C Burnham, Ian A Kennedy, Ming Lu, William J Jagust, Suzanne L Baker, Theresa M Harrison, Juan Domingo Gispert, Mahnaz Shekari, Carolina Minguillón, Ruben Smith, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Olof Strandberg, Erik Stomrud, Adam Brickman, José A Luchsinger, Jennifer J Manly, Patrick J Lao, William Charles Kreisl, Maura Malpetti, John T O'Brien, James B Rowe, Elena Jäger, Gérard N Bischof, Alexander Drzezga, Fang Xie, Xiaoxie Mao, Yihui Guan, Valentina Garibotto, Giovanni B Frisoni, Débora E Peretti, Michael Schöll, Ingmar Skoog, Silke Kern, Reisa A Sperling, Keith A Johnson, Shannon Risacher, Andrew J Saykin, Maria C Carrillo, Brad Dickerson, Liana G Apostolova, Gil D Rabinovici, Henryk Barthel, Michael Rullmann, Konstantin Messerschmidt, Rik Vandenberghe, Koen Van Laere, Laure Spruyt, Ronald Petersen, Clifford R Jack, Nicolai Franzmeier, Matthias Brendel, Johannes Gnörich, Tammie Benzinger, Julien Lagarde, Marie Sarazin, Michel Bottlaender, Sylvia Villeneuve, Judes Poirier, Sang Won Seo, Yuna Gu, Jun Pyo Kim, Beth Mormino, Christina B Young, Hillary Vossler, Pedro Rosa-Neto, Joseph Therriault, Nesrine Rahmouni, William Coath, David M Cash, Jonathan M Schott, Bernard J Hanseeuw, Yasmine Salman, Vincent Malotaux, Willemijn J Jansen, Renaud La Joie, Howard J Rosen, Sterling C Johnson, Bradley T Christian, Tobey J Betthauser, Susan M Landau, Sid E O'Bryant, Oskar Hansson, Rik Ossenkoppele, ADNI, ADNI‐DOD, A‐Study, MCSA, Prevent‐AD
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Biomarkers
Authors
Hannah de Bruin, Colin Groot, Alzheimer's Disease Neuroimaging Initiative (ADNI), Henryk Barthel, Gérard N Bischof, Ganna Blazhenets, Ronald Boellaard, Baayla D C Boon, Matthias Brendel, David M Cash, William Coath, Gregory S Day, Brad C Dickerson, Elena Doering, Alexander Drzezga, Christopher H van Dyck, Thilo van Eimeren, Wiesje M van der Flier, Carolyn A Fredericks, Tim D Fryer, Elsmarieke van de Giessen, Brian A Gordon, Jonathan Graff Radford, Lea T Grinberg, Oskar Hansson, Diana A Hobbs, Günter U Höglinger, Merle C Hönig, David J Irwin, P Simon Jones, Keith A Josephs, Yuta Katsumi, Renaud La Joie, Eddie B Lee, Johannes Levin, Maura Malpetti, Scott M McGinnis, Adam P Mecca, Rosaleena Mohanty, Ilya M Nasrallah, John T O'Brien, Ryan S O'Dell, Carla Palleis, Robert Perneczky, Jeffrey S Phillips, Deepti Putcha, Gil D Rabinovici, Nesrine Rahmouni, Pedro Rosa-Neto, James B Rowe, Michael Rullmann, Osama Sabri, Dorothee Saur, Andreas Schildan, Jonathan M Schott, Matthias L Schroeter, William W Seeley, Stijn Servaes, Irene Sintini, Ruben Smith, Salvatore Spina, Jenna Stevenson, Erik Stomrud, Olof Strandberg, Joseph Therriault, Pontus Tideman, Alexandra Touroutoglou, Anne E Trainer, Denise Visser, Fattin Wekselman, Philip Sj Weston, Jennifer L Whitwell, David A Wolk, Keir X X Yong, Yolande A L Pijnenburg, Nicolai Franzmeier, Rik Ossenkoppele
Biomarkers
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Biomarkers
Authors
Robert Durcan, Amanda J Heslegrave, Peter Swann, Julia Goddard, Leonidas Chouliaras, Henrik Zetterberg, James B Rowe, John T O'Brien, Maura Malpetti
Biomarkers
Brain communications
Published
Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy
Authors
Noah L Shapiro, Peter Simon Jones, Elijah Mak, Kamen A Tsvetanov, Julia Goddard, Davi S Vontobel, Robert Durcan, Leonidas Chouliaras, Tim Fryer, Young T Hong, Franklin Aigbirhio, Amanda Heslegrave, Nicolai Franzmeier, Matthias Brendel, Henrik Zetterberg, John T O'Brien, James B Rowe, Maura Malpetti
Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy

Malpetti Lab

Explore the work of the Malpetti Lab, focused on investigating inflammation in people living with dementia, to accelerate the development of new treatments.

A brain with PSP dementia imaged with PET-TSPO