A new study led by Prof Paul Matthews (UK DRI at Imperial) has identified a genetic link between damage to the main blood vessels of the heart, and brain small vessel disease, a common cause of vascular dementia.
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A new study led by Prof David Rubinsztein (UK DRI at Cambridge) has identified a way to enhance the cell’s ability to clear away misfolded proteins, such as those implicated in neurodegenerative diseases like Alzheimer’s.
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In a new blog post this week, Roudie Shafie, a partner at OVID Health, argues that while beating dementia is a “Herculean task”, the UK has all the necessary components in its research ecosystem to achieve real results.
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Amid ongoing negotiations about the UK’s association to Horizon Europe, the UK Government's Department for Business, Energy & Industrial Strategy (BEIS) has published a policy paper outlining how the UK will transition to a new R&D programme. UK DRI Director Prof Bart De Strooper comments on the release.
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Prof Derk-Jan Dijk (UK DRI Care Research & Technology) published an article in The Conversation discussing his latest study into sleep and dementia - read it here.
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Researchers led by Prof Karen Duff (UK DRI Centre Director at UCL) and Prof Andrew Yoo (Washington University School of Medicine) have created a new model system for studying the pathology of tau, a protein implicated in Alzheimer’s disease (AD), frontotemporal lobe dementias (FTD) and other neurodegenerative conditions, as reported in a new study published in Cell Stem Cell.
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A new study led by Dr Frances Wiseman (UK DRI at UCL) has identified a subset of genes that may protect against the accumulation of amyloid beta, a protein implicated in Alzheimer’s disease, in people who have Down syndrome. The study is published in The Journal of Neuroscience.
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The directors of four of Europe’s leading neuroscience research institutes – which together form the CURE-ND alliance (Catalysing a United Response in Europe to Neurodegeneration) – have today called upon the President of the European Commission, Ursula von der Leyen, to confirm the UK’s full association to Horizon Europe without delay.
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We are pleased to announce the latest recipients of our cross-centre postdoctoral awards – a scheme designed to stimulate exciting new academic relationships, and encourage collaboration between researchers across our seven centres.
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This World Parkinson’s Day (11 April), researchers from the UK DRI Centre at Cardiff welcomed people affected by the condition to hear about the latest cutting-edge research in the field, and discuss future therapeutic prospects for the disease. A portion of the event was broadcast virtually and can now be accessed online.
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Researchers led by Prof David Klenerman (UK DRI at Cambridge) have designed a new ‘chemical antibody’ that will help them understand the origins of neurological disorders such as Parkinson’s and Alzheimer’s disease.
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A new mouse study led by Prof Bill Wisden (UK DRI at Imperial) has found that stress can boost sleep and subsequently relieve anxiety. With emotional distress being a common symptom for those living with dementia, the findings could lead to new treatments targeting the underlying mechanism identified.
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Baroness Sally Greengross sadly passed away on 23 June this year – a loss that will be felt by the whole dementia research community.
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Members of the public gathered at the Francis Crick Institute to learn about cutting edge dementia research from scientists at ‘Dementia Demystified’, an open event run in collaboration with UK DRI to enhance public understanding of the condition.
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We are delighted to announce a collaboration with the Cell and Gene Therapy Catapult (CGTC), an Innovate UK funded organisation, to accelerate the development of AAV based gene therapy treatments.
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A novel framework that assesses the progression of Huntington’s disease, has been developed by scientists including Prof Sarah Tabrizi (UK DRI at UCL), as part of an international consortium.
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We are pleased to announce that the UK DRI has secured £1.2 million from UK Research and Innovation’s Impact Acceleration Account (IAA) to jumpstart knowledge exchange, translation and commercialisation.
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Today, we are thrilled to announce that the medical research charity LifeArc is committing £30 million over five years to the UK Dementia Research Institute, in a huge boost to our translational work.
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We are pleased to announce the eight awardees in the fourth round of the UK DRI Pilot Studies programme - an initiative designed to encourage UK DRI early career researchers to take the next step towards forming an independent lab group, and consider new and innovative avenues of research aimed at treating or advancing understanding of dementia.
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Applications for the 2022 UK DRI Prize for ‘Computational Reproducibility in Dementia Research’ are now open. We spoke to last year’s winners, PhD students Kitty Murphy and Brian Schilder, both from the UK DRI at Imperial, about their experiences, and they shared some advice and resources for anyone thinking about applying this year.
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