Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Acta Neuropathol
Published
Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model.
Authors
Sophie Quick, Tessa V Procter, Jonathan Moss, Luise Seeker, Marc Walton, Angus Lawson, Serena Baker, Anna Beletski, Daniela Jaime Garcia, Mehreen Mohammad, William Mungall, Ami Onishi, Zuzanna Tobola, Michael Stringer, Maurits A Jansen, Antoine Vallatos, Ylenia Giarratano, Miguel O Bernabeu, Joanna M Wardlaw, Anna Williams
Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model.
Cell Rep
Published
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Authors
Benjamin J Tuck, Lauren V C Miller, Taxiarchis Katsinelos, Annabel E Smith, Emma L Wilson, Sophie Keeling, Shi Cheng, Marina J Vaysburd, Claire Knox, Lucy Tredgett, Emmanouil Metzakopian, Leo C James, William A McEwan
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Exp Neurol
Published
DyNeuMo Mk-1: Design and pilot validation of an investigational motion-adaptive neurostimulator with integrated chronotherapy.
Authors
Mayela Zamora, Robert Toth, Francesca Morgante, Jon Ottaway, Tom Gillbe, Sean Martin, Guy Lamb, Tara Noone, Moaad Benjaber, Zachary Nairac, Devang Sehgal, Timothy G Constandinou, Jeffrey Herron, Tipu Z Aziz, Ivor Gillbe, Alexander L Green, Erlick A C Pereira, Timothy Denison
DyNeuMo Mk-1: Design and pilot validation of an investigational motion-adaptive neurostimulator with integrated chronotherapy.
Biosens Bioelectron
Published
Multiplexed immunosensors for point-of-care diagnostic applications.
Authors
Bruno Gil Rosa, Oluwatomi E Akingbade, Xiaotong Guo, Laura Gonzalez-Macia, Michael A Crone, Loren P Cameron, Paul Freemont, Kwang-Leong Choy, Firat Güder, Eric Yeatman, David J Sharp, Bing Li
Multiplexed immunosensors for point-of-care diagnostic applications.
Biosens Bioelectron
Published
Multiplexed immunosensors for point-of-care diagnostic applications.
Authors
Bruno Gil Rosa, Oluwatomi E Akingbade, Xiaotong Guo, Laura Gonzalez-Macia, Michael A Crone, Loren P Cameron, Paul Freemont, Kwang-Leong Choy, Firat Güder, Eric Yeatman, David J Sharp, Bing Li
Multiplexed immunosensors for point-of-care diagnostic applications.
Nature
Published
Somatic mosaicism reveals clonal distributions of neocortical development.
Authors
Martin W Breuss, Xiaoxu Yang, Johannes C M Schlachetzki, Danny Antaki, Addison J Lana, Xin Xu, Changuk Chung, Guoliang Chai, Valentina Stanley, Qiong Song, Traci F Newmeyer, An Nguyen, Sydney O'Brien, Marten A Hoeksema, Beibei Cao, Alexi Nott, Jennifer McEvoy-Venneri, Martina P Pasillas, Scott T Barton, Brett R Copeland, Shareef Nahas, Lucitia Van Der Kraan, Yan Ding, Christopher K Glass, Joseph G Gleeson
Somatic mosaicism reveals clonal distributions of neocortical development.
Nature
Published
Somatic mosaicism reveals clonal distributions of neocortical development.
Authors
Martin W Breuss, Xiaoxu Yang, Johannes C M Schlachetzki, Danny Antaki, Addison J Lana, Xin Xu, Changuk Chung, Guoliang Chai, Valentina Stanley, Qiong Song, Traci F Newmeyer, An Nguyen, Sydney O'Brien, Marten A Hoeksema, Beibei Cao, Alexi Nott, Jennifer McEvoy-Venneri, Martina P Pasillas, Scott T Barton, Brett R Copeland, Shareef Nahas, Lucitia Van Der Kraan, Yan Ding, , Christopher K Glass, Joseph G Gleeson
Somatic mosaicism reveals clonal distributions of neocortical development.
J Neurosci
Published
Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice.
Authors
Paula de Oliveira, Claire Cella, Nicolas Locker, Kiran K G Ravindran, Agampodi Mendis, Keith Wafford, Gary Gilmour, Derk-Jan Dijk, Raphaelle Winsky-Sommerer
Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice.
J Neurosci
Published
Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice.
Authors
Paula de Oliveira, Claire Cella, Nicolas Locker, Kiran K G Ravindran, Agampodi Mendis, Keith Wafford, Gary Gilmour, Derk-Jan Dijk, Raphaelle Winsky-Sommerer
Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice.