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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Sleep
Published
Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: association with more slow waves and daytime sleepiness.
Authors
Vincenzo Muto, Ekaterina Koshmanova, Pouya Ghaemmaghami, Mathieu Jaspar, Christelle Meyer, Mahmoud Elansary, Maxime Van Egroo, Daphne Chylinski, Christian Berthomier, Marie Brandewinder, Charlotte Mouraux, Christina Schmidt, Grégory Hammad, Wouter Coppieters, Naima Ahariz, Christian Degueldre, André Luxen, Eric Salmon, Christophe Phillips, Simon N Archer, Loic Yengo, Enda Byrne, Fabienne Collette, Michel Georges, Derk-Jan Dijk, Pierre Maquet, Peter M Visscher, Gilles Vandewalle
Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: association with more slow waves and daytime sleepiness.
Sleep
Published
Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: association with more slow waves and daytime sleepiness.
Authors
Vincenzo Muto, Ekaterina Koshmanova, Pouya Ghaemmaghami, Mathieu Jaspar, Christelle Meyer, Mahmoud Elansary, Maxime Van Egroo, Daphne Chylinski, Christian Berthomier, Marie Brandewinder, Charlotte Mouraux, Christina Schmidt, Grégory Hammad, Wouter Coppieters, Naima Ahariz, Christian Degueldre, André Luxen, Eric Salmon, Christophe Phillips, Simon N Archer, Loic Yengo, Enda Byrne, Fabienne Collette, Michel Georges, Derk-Jan Dijk, Pierre Maquet, Peter M Visscher, Gilles Vandewalle
Alzheimer's disease genetic risk and sleep phenotypes in healthy young men: association with more slow waves and daytime sleepiness.
Acta Neuropathol
Published
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.
Authors
Arpan R Mehta, Jenna M Gregory, Owen Dando, Roderick N Carter, Karen Burr, Jyoti Nanda, David Story, Karina McDade, Colin Smith, Nicholas M Morton, Don J Mahad, Giles E Hardingham, Siddharthan Chandran, Bhuvaneish T Selvaraj
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.
Brain Commun
Published
Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective.
Authors
Charis Wong, Maria Stavrou, Elizabeth Elliott, Jenna M Gregory, Nigel Leigh, Ashwin A Pinto, Timothy L Williams, Jeremy Chataway, Robert Swingler, Mahesh K B Parmar, Nigel Stallard, Christopher J Weir, Richard A Parker, Amina Chaouch, Hisham Hamdalla, John Ealing, George Gorrie, Ian Morrison, Callum Duncan, Peter Connelly, Francisco Javier Carod-Artal, Richard Davenport, Pablo Garcia Reitboeck, Aleksandar Radunovic, Venkataramanan Srinivasan, Jenny Preston, Arpan R Mehta, Danielle Leighton, Stella Glasmacher, Emily Beswick, Jill Williamson, Amy Stenson, Christine Weaver, Judith Newton, Dawn Lyle, Rachel Dakin, Malcolm Macleod, Suvankar Pal, Siddharthan Chandran
Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective.
Nat Commun
Published
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Authors
Daniel Jutzi, Sébastien Campagne, Ralf Schmidt, Stefan Reber, Jonas Mechtersheimer, Foivos Gypas, Christoph Schweingruber, Martino Colombo, Christine von Schroetter, Fionna E Loughlin, Anny Devoy, Eva Hedlund, Mihaela Zavolan, Frédéric H-T Allain, Marc-David Ruepp
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun
Published
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Authors
Daniel Jutzi, Sébastien Campagne, Ralf Schmidt, Stefan Reber, Jonas Mechtersheimer, Foivos Gypas, Christoph Schweingruber, Martino Colombo, Christine von Schroetter, Fionna E Loughlin, Anny Devoy, Eva Hedlund, Mihaela Zavolan, Frédéric H-T Allain, Marc-David Ruepp
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun
Published
Cerebral small vessel disease genomics and its implications across the lifespan.
Authors
Muralidharan Sargurupremraj, Hideaki Suzuki, Xueqiu Jian, Chloé Sarnowski, Tavia E Evans, Joshua C Bis, Gudny Eiriksdottir, Saori Sakaue, Natalie Terzikhan, Mohamad Habes, Wei Zhao, Nicola J Armstrong, Edith Hofer, Lisa R Yanek, Saskia P Hagenaars, Rajan B Kumar, Erik B van den Akker, Rebekah E McWhirter, Stella Trompet, Aniket Mishra, Yasaman Saba, Claudia L Satizabal, Gregory Beaudet, Laurent Petit, Ami Tsuchida, Laure Zago, Sabrina Schilling, Sigurdur Sigurdsson, Rebecca F Gottesman, Cora E Lewis, Neelum T Aggarwal, Oscar L Lopez, Jennifer A Smith, Maria C Valdés Hernández, Jeroen van der Grond, Margaret J Wright, Maria J Knol, Marcus Dörr, Russell J Thomson, Constance Bordes, Quentin Le Grand, Marie-Gabrielle Duperron, Albert V Smith, David S Knopman, Pamela J Schreiner, Denis A Evans, Jerome I Rotter, Alexa S Beiser, Susana Muñoz Maniega, Marian Beekman, Julian Trollor, David J Stott, Meike W Vernooij, Katharina Wittfeld, Wiro J Niessen, Aicha Soumaré, Eric Boerwinkle, Stephen Sidney, Stephen T Turner, Gail Davies, Anbupalam Thalamuthu, Uwe Völker, Mark A van Buchem, R Nick Bryan, Josée Dupuis, Mark E Bastin, David Ames, Alexander Teumer, Philippe Amouyel, John B Kwok, Robin Bülow, Ian J Deary, Peter R Schofield, Henry Brodaty, Jiyang Jiang, Yasuharu Tabara, Kazuya Setoh, Susumu Miyamoto, Kazumichi Yoshida, Manabu Nagata, Yoichiro Kamatani, Fumihiko Matsuda, Bruce M Psaty, David A Bennett, Philip L De Jager, Thomas H Mosley, Perminder S Sachdev, Reinhold Schmidt, Helen R Warren, Evangelos Evangelou, David-Alexandre Trégouët, , , Mohammad A Ikram, Wei Wen, Charles DeCarli, Velandai K Srikanth, J Wouter Jukema, Eline P Slagboom, Sharon L R Kardia, Yukinori Okada, Bernard Mazoyer, Joanna M Wardlaw, Paul A Nyquist, Karen A Mather, Hans J Grabe, Helena Schmidt, Cornelia M Van Duijn, Vilmundur Gudnason, William T Longstreth, Lenore J Launer, Mark Lathrop, Sudha Seshadri, Christophe Tzourio, Hieab H Adams, Paul M Matthews, Myriam Fornage, Stéphanie Debette
Cerebral small vessel disease genomics and its implications across the lifespan.