Skip to main content
Search
Main content

Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Brain : a journal of neurology
Published
Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum
Authors
Jaime Fernández Arias, Wagner S Brum, Gemma Salvadó, Joseph Therriault, Stijn Servaes, Yi-Ting Wang, Etienne Aumont, Nesrine Rahmouni, Arthur Macedo, Kely Quispialaya, Seyyed Ali Hosseini, Peter Kunach, Wan Lu Jia, Tevy Chan, Lydia Trudel, Brandon Hall, Yanseng Zheng, Sejal Mohapatra, Sulantha S Mathotaarachchi, Paolo Vitali, Cécile Tissot, Gleb Bezgin, Yasser Iturria-Medina, Nicholas J Ashton, Andréa Lessa Benedet, Thomas K Karikari, Gallen Triana-Baltzer, Jesse Klostranec, Hartmuth C Kolb, Eduardo R Zimmer, Shorena Janelidze, Niklas Mattson-Carlgren, Erik Stomrud, Sebastian Palmqvist, Henrik Zetterberg, Kaj Blennow, Tharick Pascoal, Maxime Montembeault, Oskar Hansson, Pedro Rosa-Neto
Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum
Journal of neuroinflammation
Published
Characteristics of TSPO expression in marmoset EAE
Authors
Irene Falk, Dragan Maric, Emily Leibovitch, Pascal Sati, Jennifer Lefeuvre, Nicholas J Luciano, Joseph Guy, Seung-Kwon Ha, David R Owen, Franklin Aigbirhio, Paul M Matthews, Daniel S Reich, Steven Jacobson
Characteristics of TSPO expression in marmoset EAE
Nature communications
Published
Splicing accuracy varies across human introns, tissues, age and disease
Authors
S García-Ruiz, D Zhang, E K Gustavsson, G Rocamora-Perez, M Grant-Peters, A Fairbrother-Browne, R H Reynolds, J W Brenton, A L Gil-Martínez, Z Chen, D C Rio, J A Botia, S Guelfi, L Collado-Torres, M Ryten
Splicing accuracy varies across human introns, tissues, age and disease
European psychiatry : the journal of the Association of European Psychiatrists
Published
Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts
Authors
A J Edmondson-Stait, E Davyson, X Shen, M J Adams, G M Khandaker, V E Miron, A M McIntosh, S M Lawrie, A S F Kwong, H C Whalley
Associations between IL-6 and trajectories of depressive symptoms across the life course: Evidence from ALSPAC and UK Biobank cohorts
bioRxiv : the preprint server for biology
Published
Gene expression patterns of the developing human face at single cell resolution reveal cell type contributions to normal facial variation and disease risk
Authors
Nagham Khouri-Farah, Emma Wentworth Winchester, Brian M Schilder, Kelsey Robinson, Sarah W Curtis, Nathan G Skene, Elizabeth J Leslie-Clarkson, Justin Cotney
Gene expression patterns of the developing human face at single cell resolution reveal cell type contributions to normal facial variation and disease risk
Medicina (Kaunas, Lithuania)
Published
Functional and Cognitive Impairment in Patients with Relapsing-Remitting Multiple Sclerosis: Cognitive Tests and Plasma Neurofilament Light Chain Levels
Authors
Elina Polunosika, Joel Simren, Arta Akmene, Nikita Klimovskis, Kaj Blennow, Daina Pastare, Henrik Zetterberg, Renars Erts, Guntis Karelis
Functional and Cognitive Impairment in Patients with Relapsing-Remitting Multiple Sclerosis: Cognitive Tests and Plasma Neurofilament Light Chain Levels
Clinical epigenetics
Published
Blood-based epigenome-wide association study and prediction of alcohol consumption
Authors
Elena Bernabeu, Aleksandra D Chybowska, Jacob K Kresovich, Matthew Suderman, Daniel L McCartney, Robert F Hillary, Janie Corley, Maria Del C Valdés-Hernández, Susana Muñoz Maniega, Mark E Bastin, Joanna M Wardlaw, Zongli Xu, Dale P Sandler, Archie Campbell, Sarah E Harris, Andrew M McIntosh, Jack A Taylor, Paul Yousefi, Simon R Cox, Kathryn L Evans, Matthew R Robinson, Catalina A Vallejos, Riccardo E Marioni
Blood-based epigenome-wide association study and prediction of alcohol consumption
Cell chemical biology
Published
SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
Authors
Shekhar Kedia, Emre Fertan, Yunzhao Wu, Yu P Zhang, Georg Meisl, Jeff Y L Lam, Frances K Wiseman, William A McEwan, Annelies Quaegebeur, Maria Grazia Spillantini, John S H Danial, David Klenerman
SynPull: An advanced method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
Alzheimer's & dementia : the journal of the Alzheimer's Association
Published
Polygenic risk discriminates Lewy body dementia from Alzheimer's disease
Authors
Anna McKeever, Peter Swann, Maura Malpetti, Paul C Donaghy, Alan Thomas, Elijah Mak, Stephen F Carter, Jerry H K Tan, Young T Hong, Tim D Fryer, Amanda Heslegrave, Henrik Zetterberg, Li Su, Leonidas Chouliaras, James B Rowe, John T O'Brien
Polygenic risk discriminates Lewy body dementia from Alzheimer's disease