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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Scientific reports
Published
Associations of inferior frontal sulcal hyperintensities on brain MRI with cerebral small vessel disease, cognitive function, and depression symptoms
Authors
Marc Dörner, Malte Pfister, Anthony Tyndall, Roland von Känel, Katja Neumann, Frank Schreiber, Philipp Arndt, Erelle Fuchs, Cornelia Garz, Wenzel Glanz, Michaela Butryn, Anna-Charlotte John, Annkatrin Hildebrand, Sebastian Euler, Andreas B Hofmann, Lena Machetanz, Johannes Kirchebner, Pawel Tacik, Alexander Grimm, Robin Jansen, Marc Pawlitzki, Solveig Henneicke, Valentina Perosa, Bendix Labeit, Emrah Düzel, Sven G Meuth, Stefan Vielhaber, Hendrik Mattern, Jose Bernal, Stefanie Schreiber
Associations of inferior frontal sulcal hyperintensities on brain MRI with cerebral small vessel disease, cognitive function, and depression symptoms
Brain communications
Published
Identify biological Alzheimer's disease using a novel nucleic acid-linked protein immunoassay
Authors
Yi-Ting Wang, Nicholas J Ashton, Joseph Therriault, Andréa L Benedet, Arthur C Macedo, Ilaria Pola, Etienne Aumont, Guglielmo Di Molfetta, Jaime Fernandez-Arias, Kubra Tan, Nesrine Rahmouni, Stijn Johannes G Servaes, Richard Isaacson, Tevy Chan, Seyyed Ali Hosseini, Cécile Tissot, Sulantha Mathotaarachchi, Jenna Stevenson, Firoza Z Lussier, Tharick A Pascoal, Serge Gauthier, Kaj Blennow, Henrik Zetterberg, Pedro Rosa-Neto
Identify biological Alzheimer's disease using a novel nucleic acid-linked protein immunoassay
JAMA network open
Published
Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study
Authors
Julie E Oomens, Veerle van Gils, Stephanie J B Vos, Whitney M Freeze, Nancy N Maserejian, Gioacchino Curiale, Cai Gillis, Mercè Boada, Wiesje M van der Flier, Jakub Hort, Sterling C Johnson, Alberto Lleó, Inez H Ramakers, Karen M Rodrigue, Pascual Sánchez-Juan, Marie Sarazin, Nikolaos Scarmeas, Henrik Zetterberg, Daniel Alcolea, Frederik Barkhof, Kaj Blennow, Michel Bottlaender, Anouk den Braber, Jirí Cerman, Marta Drake-Perez, Juan Fortea, Ron Handels, Silvia Ingala, Julio F Jiménez-Bonilla, Stratos Karavasilis, Julien Lagarde, Nienke Legdeur, Luigi Lorenzini, Marta Marquié, Justine E F Moonen, Pauline Olivieri, Adelina Orellana, Rik Ossenkoppele, Leonardo A Rivera-Rivera, Eloy Rodríguez-Rodriguez, Agustín Ruiz Laza, Charlotte E Teunissen, Betty M Tijms, Giorgos Velonakis, Frans R J Verhey, Pieter Jelle Visser, Willemijn J Jansen, European Prevention of Alzheimer’s Dementia (EPAD) Consortium, Fundació ACE Healthy Brain Initiative (FACEHBI) Study Group, BIOFACE Study Group
Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study
JAMA psychiatry
Published
Depressive Symptoms and Amyloid Pathology
Authors
Wietse A Wiels, Julie E Oomens, Sebastiaan Engelborghs, Chris Baeken, Christine A F von Arnim, Mercè Boada, Mira Didic, Bruno Dubois, Tormod Fladby, Wiesje M van der Flier, Giovanni B Frisoni, Lutz Fröhlich, Kiran Dip Gill, Timo Grimmer, Helmut Hildebrandt, Jakub Hort, Yoshiaki Itoh, Takeshi Iwatsubo, Aleksandra Klimkowicz-Mrowiec, Dong Young Lee, Alberto Lleó, Pablo Martinez-Lage, Alexandre de Mendonça, Philipp T Meyer, Elisabeth N Kapaki, Piero Parchi, Matteo Pardini, Lucilla Parnetti, Julius Popp, Lorena Rami, Eric M Reiman, Juha O Rinne, Karen M Rodrigue, Pascual Sánchez-Juan, Isabel Santana, Marie Sarazin, Nikolaos Scarmeas, Ingmar Skoog, Peter J Snyder, Reisa A Sperling, Sylvia Villeneuve, Anders Wallin, Jens Wiltfang, Henrik Zetterberg, Rik Ossenkoppele, Frans R J Verhey, Stephanie J B Vos, Pieter Jelle Visser, Willemijn J Jansen, Amyloid Biomarker Study group, Alzheimer’s Disease Neuroimaging Initiative (ADNI), the A4 Study group, Dominantly Inherited Alzheimer Network (DIAN), European Prevention of Alzheimer’s Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI), Harvard Aging Brain Stud, Daniel Alcolea, Daniele Altomare, Simone Baiardi, Ines Baldeiras, Randall J Bateman, Kaj Blennow, Michel Bottlaender, Anouk den Braber, Mark A van Buchem, Min Soo Byun, Jirí Cerman, Kewei Chen, Elena Chipi, Gregory S Day, Alexander Drzezga, Marie Eckerström, Laura L Ekblad, Stéphane Epelbaum, Stefan Förster, Juan Fortea, Yvonne Freund-Levi, Lars Frings, Eric Guedj, Lucrezia Hausner, Sabine Hellwig, Edward D Huey, Julio F Jiménez-Bonilla, Keith A Johnson, Ane Iriondo Juaristi, Ramesh Kandimalla, George Paraskevas, Silke Kern, Bjørn-Eivind S Kirsebom, Johannes Kornhuber, Julien Lagarde, Susan M Landau, Nienke Legdeur, Jorge J Llibre Guerra, Nancy N Maserejian, Marta Marquié, Shinobu Minatani, Silvia Daniela Morbelli, Barbara Mroczko, Eva Ntanasi, Catarina Resende de Oliveira, Pauline Olivieri, Adelina Orellana, Richard J Perrin, Oliver Peters, Sudesh Prabhakar, Inez H Ramakers, Eloy Rodríguez-Rodriguez, Agustín Ruiz, Eckart Rüther, Per Selnes, Dina Silva, Hilkka Soininen, Luiza Spiru, Akitoshi Takeda, Marc Teichmann, Betty M Tijms, Charlotte E Teunissen, Loisa I Thompson, Jonathan Vogelgsangs, Jonathan Vöglein, Gunhild Waldemar, Åsa K Wallin, Mary Yannakoulia, Dahyun Yi, Anna Zettergren
Depressive Symptoms and Amyloid Pathology
The Clinical neuropsychologist
Published
Single- versus two-test criteria for cognitive impairment: associations with CSF and imaging markers in former American football players
Authors
Monica T Ly, Caroline Altaras, Yorghos Tripodis, Charles H Adler, Laura J Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Elaine R Peskind, Sarah J Banks, William B Barr, Jennifer V Wethe, Steve Lenio, Mark W Bondi, Lisa M Delano-Wood, Robert C Cantu, Michael J Coleman, David W Dodick, Jesse Mez, Daniel H Daneshvar, Joseph N Palmisano, Brett Martin, Alexander P Lin, Inga K Koerte, Sylvain Bouix, Jeffrey L Cummings, Eric M Reiman, Martha E Shenton, Robert A Stern, Michael L Alosco
Single- versus two-test criteria for cognitive impairment: associations with CSF and imaging markers in former American football players
Aging cell
Published
Assessing Metabolic Ageing via DNA Methylation Surrogate Markers: A Multicohort Study in Britain, Ireland and the USA
Authors
Kexin Xu, Belinda Hernández, Thalida Em Arpawong, Stephane Camuzeaux, Elena Chekmeneva, Eileen M Crimmins, Paul Elliott, Giovani Fiorito, Beatriz Jiménez, Rose Anne Kenny, Cathal McCrory, Sinead McLoughlin, Rui Pinto, Caroline Sands, Paolo Vineis, Chung-Ho E Lau, Oliver Robinson
Assessing Metabolic Ageing via DNA Methylation Surrogate Markers: A Multicohort Study in Britain, Ireland and the USA
medRxiv : the preprint server for health sciences
Published
Predilection for Perplexion: Preoperative microstructural damage is linked to postoperative delirium
Authors
Tyler H Reekes, Vinith R Upadhya, Jenna L Merenstein, Mary Cooter-Wright, David J Madden, Melody A Reese, Piper C Boykin, Noah J Timko, Judd W Moul, Grant E Garrigues, Katherine T Martucci, Harvey Jay Cohen, Heather E Whitson, Joseph P Mathew, Michael J Devinney, Henrik Zetterberg, Kaj Blennow, Leslie M Shaw, Teresa Waligorska, Jeffrey N Browndyke, Miles Berger, MADCO-PC and INTUIT Investigators
Predilection for Perplexion: Preoperative microstructural damage is linked to postoperative delirium
Biological psychiatry
Published
MAPPING THE CEREBROSPINAL FLUID PROTEOME IN BIPOLAR DISORDER
Authors
Andreas Göteson, Jessica Holmén-Larsson, Hatice Celik, Aurimantas Pelanis, Carl M Sellgren, Timea Sparding, Erik Pålsson, Henrik Zetterberg, Kaj Blennow, Lina Jonsson, Johan Gobom, Mikael Landén
MAPPING THE CEREBROSPINAL FLUID PROTEOME IN BIPOLAR DISORDER
Annals of neurology
Published
Clinical Relevance of 'Cap' and 'Track' Development after Recent Small Subcortical Infarct
Authors
Yajun Cheng, Carmen Arteaga-Reyes, Una Clancy, Daniela Jaime Garcia, Maria Del C Valdés Hernández, Michael J Thrippleton, Michael S Stringer, Gordon W Blair, Stewart Wiseman, Francesca M Chappell, Junfang Zhang, Xiaodi Liu, Angela C C Jochems, Susana Muñoz Maniega, Eleni Sakka, Mark E Bastin, Rosalind Brown, Caroline M J Loos, Stephen D J Makin, Ming Liu, Bo Wu, Fergus N Doubal, Joanna M Wardlaw, MSS‐2, MSS‐3 and the INVESTIGATE‐SVDs Study Group
Clinical Relevance of 'Cap' and 'Track' Development after Recent Small Subcortical Infarct
Scientific reports
Published
Association between herpes simplex virus infection and Alzheimer's disease biomarkers: analysis within the MAPT trial
Authors
Morgane Linard, Isabelle Garrigue, Bruno Vellas, Nicola Coley, Henrik Zetterberg, Kaj Blennow, Nicholas James Ashton, Pierre Payoux, Anne-Sophie Salabert, Jean-François Dartigues, Joachim Mazere, Sandrine Andrieu, Catherine Helmer
Association between herpes simplex virus infection and Alzheimer's disease biomarkers: analysis within the MAPT trial