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Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Therapeutic advances in neurological disorders
Published
Differential risk factor profile and neuroimaging markers of small vessel disease between lacunar ischemic stroke and deep intracerebral hemorrhage
Authors
Yajun Cheng, Maria Del C Valdés Hernández, Mangmang Xu, Shuting Zhang, Xiaohua Pan, Baoqiang An, Joanna M Wardlaw, Ming Liu, Bo Wu
Differential risk factor profile and neuroimaging markers of small vessel disease between lacunar ischemic stroke and deep intracerebral hemorrhage
Cell reports
Published
The neuron mixer and its impact on human brain dynamics
Authors
Charlotte E Luff, Robert Peach, Emma-Jane Mallas, Edward Rhodes, Felix Laumann, Edward S Boyden, David J Sharp, Mauricio Barahona, Nir Grossman
The neuron mixer and its impact on human brain dynamics
Nature biotechnology
Published
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq
Authors
Bernardo Aguzzoli Heberle, J Anthony Brandon, Madeline L Page, Kayla A Nations, Ketsile I Dikobe, Brendan J White, Lacey A Gordon, Grant A Fox, Mark E Wadsworth, Patricia H Doyle, Brittney A Williams, Edward J Fox, Anantharaman Shantaraman, Mina Ryten, Sara Goodwin, Elena Ghiban, Robert Wappel, Senem Mavruk-Eskipehlivan, Justin B Miller, Nicholas T Seyfried, Peter T Nelson, John D Fryer, Mark T W Ebbert
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq
Human molecular genetics
Published
PSMC5 insufficiency and P320R mutation impair proteasome function
Authors
Zhong-Qiu Yu, Jenny Carmichael, Galen A Collins, Maria Daniela D'Agostino, Mathieu Lessard, Helen V Firth, Pooja Harijan, Andrew E Fry, John Dean, Jiuchun Zhang, Usha Kini, Alfred L Goldberg, David C Rubinsztein
PSMC5 insufficiency and P320R mutation impair proteasome function
JAMA network open
Published
Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia
Authors
Muralidharan Sargurupremraj, Aicha Soumaré, Joshua C Bis, Ida Surakka, Tuuli Jürgenson, Pierre Joly, Maria J Knol, Ruiqi Wang, Qiong Yang, Claudia L Satizabal, Alexander Gudjonsson, Aniket Mishra, Vincent Bouteloup, Chia-Ling Phuah, Cornelia M van Duijn, Carlos Cruchaga, Carole Dufouil, Geneviève Chêne, Oscar L Lopez, Bruce M Psaty, Christophe Tzourio, Philippe Amouyel, Hieab H Adams, Hélène Jacqmin-Gadda, Mohammad Arfan Ikram, Vilmundur Gudnason, Lili Milani, Bendik S Winsvold, Kristian Hveem, Paul M Matthews, W T Longstreth, Sudha Seshadri, Lenore J Launer, Stéphanie Debette
Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia
Cell reports
Published
Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity
Authors
Anirudh Patir, Jack Barrington, Stefan Szymkowiak, Gaia Brezzo, Dana Straus, Alessio Alfieri, Lucas Lefevre, Zhaoyuan Liu, Florent Ginhoux, Neil C Henderson, Karen Horsburgh, Prakash Ramachandran, Barry W McColl
Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity
Neuro-degenerative diseases
Published
The Taxonomy of Subjective Cognitive Decline: Proposal and First Clinical Evidence from the Geneva Memory Clinic Cohort
Authors
Federica Ribaldi, Rafael Palomo, Daniele Altomare, Max Scheffler, Frederic Assal, Nicholas J Ashton, Henrik Zetterberg, Kaj Blennow, Marc Abramowicz, Valentina Garibotto, Christian Chicherio, Giovanni B Frisoni
The Taxonomy of Subjective Cognitive Decline: Proposal and First Clinical Evidence from the Geneva Memory Clinic Cohort