Publications

Our scientific output and findings

From groundbreaking discoveries in basic science to innovative clinical insights, our publications showcase the breadth and depth of research taking place at the UK DRI. 

Featured

Cytokines released by T cells after encountering cancer cells

A balancing act: preventing an overactive immune system

Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity. The study, led by Prof Jernej Ule (UK DRI at King's)...

Learn more A balancing act: preventing an overactive immune system
Brain Pathol
Published

The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome.

Authors
Benjamin J Cooze, Matthew Dickerson, Rukshikah Loganathan, Lewis M Watkins, Ethan Grounds, Ben R Pearson, Ryan Jack Bevan, B Paul Morgan, Roberta Magliozzi, Richard Reynolds, James W Neal, Owain W Howell
The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome.
Nat Commun
Published

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.

Authors
Zoeb Jiwaji, Sachin S Tiwari, Rolando X Avilés-Reyes, Monique Hooley, David Hampton, Megan Torvell, Delinda A Johnson, Jamie McQueen, Paul Baxter, Kayalvizhi Sabari-Sankar, Jing Qiu, Xin He, Jill Fowler, James Febery, Jenna Gregory, Jamie Rose, Jane Tulloch, Jamie Loan, David Story, Karina McDade, Amy M Smith, Peta Greer, Matthew Ball, Peter C Kind, Paul M Matthews, Colin Smith, Owen Dando, Tara L Spires-Jones, Jeffrey A Johnson, Siddharthan Chandran, Giles E Hardingham
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Nat Commun
Published

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.

Authors
Zoeb Jiwaji, Sachin S Tiwari, Rolando X Avilés-Reyes, Monique Hooley, David Hampton, Megan Torvell, Delinda A Johnson, Jamie McQueen, Paul Baxter, Kayalvizhi Sabari-Sankar, Jing Qiu, Xin He, Jill Fowler, James Febery, Jenna Gregory, Jamie Rose, Jane Tulloch, Jamie Loan, David Story, Karina McDade, Amy M Smith, Peta Greer, Matthew Ball, Peter C Kind, Paul M Matthews, Colin Smith, Owen Dando, Tara L Spires-Jones, Jeffrey A Johnson, Siddharthan Chandran, Giles E Hardingham
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Dev Cell
Published

iPSC-derived myelinoids to study myelin biology of humans.

Authors
Owen G James, Bhuvaneish T Selvaraj, Dario Magnani, Karen Burr, Peter Connick, Samantha K Barton, Navneet A Vasistha, David W Hampton, David Story, Robert Smigiel, Rafal Ploski, Peter J Brophy, Charles Ffrench-Constant, David A Lyons, Siddharthan Chandran
iPSC-derived myelinoids to study myelin biology of humans.
Dev Cell
Published

iPSC-derived myelinoids to study myelin biology of humans.

Authors
Owen G James, Bhuvaneish T Selvaraj, Dario Magnani, Karen Burr, Peter Connick, Samantha K Barton, Navneet A Vasistha, David W Hampton, David Story, Robert Smigiel, Rafal Ploski, Peter J Brophy, Charles Ffrench-Constant, David A Lyons, Siddharthan Chandran
iPSC-derived myelinoids to study myelin biology of humans.
Front Comput Neurosci
Published

Recent Trends in Non-invasive Neural Recording Based Brain-to-Brain Synchrony Analysis on Multidisciplinary Human Interactions for Understanding Brain Dynamics: A Systematic Review.

Authors
Tahnia Nazneen, Iffath Binta Islam, Md Sakibur Rahman Sajal, Wasifa Jamal, M Ashraful Amin, Ravi Vaidyanathan, Tom Chau, Khondaker A Mamun
Recent Trends in Non-invasive Neural Recording Based Brain-to-Brain Synchrony Analysis on Multidisciplinary Human Interactions for Understanding Brain Dynamics: A Systematic Review.
J Struct Biol
Published

Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2.

Authors
Antonette Bennett, Joshua Hull, Nelly Jolinon, Julie Tordo, Katie Moss, Enswert Binns, Mario Mietzsch, Cathleen Hagemann, R Michael Linden, Andrea Serio, Paul Chipman, Duncan Sousa, Felix Broecker, Peter Seeberger, Els Henckaerts, Robert McKenna, Mavis Agbandje-McKenna
Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2.
Molecules
Published

Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis.

Authors
Sonia Burgaz, Concepción García, Claudia Gonzalo-Consuegra, Marta Gómez-Almería, Francisco Ruiz-Pino, Juan Diego Unciti, María Gómez-Cañas, Juan Alcalde, Paula Morales, Nadine Jagerovic, Carmen Rodríguez-Cueto, Eva de Lago, Eduardo Muñoz, Javier Fernández-Ruiz
Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis.