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Lancet (London, England)
Published

Alzheimer's disease

Authors

Alberto Serrano-Pozo, Valentina Escott-Price, Lea T Grinberg, Tharick Pascoal, Marc Suárez-Calvet, Bruno Dubois, Reisa A Sperling

Abstract

Lancet. 2026 May 30;407(10544):2241-2262. doi: 10.1016/S0140-6736(26)00198-4.

ABSTRACT

Alzheimer's disease is the leading cause of dementia and among the top ten leading causes of death in high-income countries. Exponential advances in epidemiology, genetics, diagnostic imaging and fluid biomarkers, treatment, and prevention in the last decade reinforce the notion that we are entering a new era in the clinical management of Alzheimer's disease. However, far from triumphalism, this momentum should be accelerated to achieve the goals of preventing Alzheimer's disease and arresting its progression. In this Seminar, we summarise this progress and highlight unmet needs and areas of research priority.

PMID:42208565 | DOI:10.1016/S0140-6736(26)00198-4

UK DRI Authors

Prof Valentina Escott-Price

Group Leader

Using Big Data, machine learning and AI to accelerate discoveries into dementia

Prof Valentina Escott-Price