Characterization of overnight slow-wave slope changes across development in an age-, amplitude-, and region-dependent manner.

Abstract

The restorative function of sleep has been linked to a net reduction in synaptic strength. The slope of slow-waves, a major characteristic of non-rapid eye movement (NREM) sleep, has been shown to directly reflect synaptic strength, when accounting for amplitude changes across the night. In this study, we aimed to investigate overnight slope changes in the course of development in an age-, amplitude-, and region-dependent manner.

PMID:32154557 | DOI:10.1093/sleep/zsaa038