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Ann Neurol
Published

Thalamic Influence on Slow Wave Slope Renormalization During Sleep.

Authors

Valeria Jaramillo, Jasmine Jendoubi, Angelina Maric, Armand Mensen, Natalie C Heyse, Aleksandra K Eberhard-Moscicka, Roland Wiest, Claudio L A Bassetti, Reto Huber

Abstract

Slow waves are thought to mediate an overall reduction in synaptic strength during sleep. The specific contribution of the thalamus to this so-called synaptic renormalization is unknown. Thalamic stroke is associated with daytime sleepiness, along with changes to sleep electroencephalography and cognition, making it a unique "experiment of nature" to assess the relationship between sleep rhythms, synaptic renormalization, and daytime functions.

PMID:34516002 | DOI:

UK DRI Authors

Valeria jaramillo profile

Dr Valeria Jaramillo

Emerging Leader

Using multimodal approaches to evaluate interventions to improve REM sleep in ageing and dementia

Dr Valeria Jaramillo