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Dr Audrey Chagnot

PhD

Postdoctoral Researcher

Blood brain barrier, pericytes, brain ageing, dementia

Techniques

Advanced microscopy & imaging, Mouse in vivo imaging

Biography

I joined the Montagne lab in February 2022. I completed my PhD in the Pathophysiology and Imaging of Neurological Disorders team (INSERM U1237) at the University of Caen Normandy, France, where I developped Magnetic Resonance Imaging protocols to study the glymphatic system in mice.

Research interest

I focus my research within the Montagne Lab on understanding how the pericytes regulate the neurovascular coupling and the blood-brain barrier permeability in brain capillaries. For this purpose, I developed image processing tool for microscopy to investigate subtle changes in cellular morphology. By understanding the fundamental mechanisms behind microvascular dysfunction, I aim to discover new therapeutic options against brain ageing and dementia.

Key publications

Links

Links