Biography
Frances holds a BA from the University of Oxford, and a MRes and PhD from the University of Edinburgh, and in 2018 she was awarded an Alzheimer’s Research UK Senior Fellowship. She has particular expertise in the use of genetically altered animal models for the study of neurological disease. Reflecting this she sits on the executive board of the Medical Research Council National Mouse Genetics Network. Dr. Wiseman’s research focus is the early-onset of Alzheimer’s disease in people who have Down syndrome, using a range of research approaches. She is an active member of the Trisomy 21 Research Society, co-chairing the society's preclinical committee and sitting on the society’s Executive Board.
UK DRI Programme Leader for Animal Models
In addition to her research programme, Dr Frances Wiseman is the ‘UK DRI Programme Leader for Animal Models’. The utilisation of mammalian animal models is fundamental to much of the research that takes place in the dementia field, and basic biomedical investigation as a whole. However, there is still much to be done to refine these models so that the research translates into the development of effective therapeutics in the clinic.
As part of the role, Frances develops a collaborative programme and directs a team effort to improve the value of genetically and non-genetically modified rodent models in dementia research. The UK DRI are particularly interested in innovative technologies to analyse brain function in vivo, and novel ways to create better models for disease. From the UK DRI at UCL and MRC Harwell, Frances will coordinate this massive effort and be the first point of contact for enquiries related to animal research.
Wiseman Lab
Explore the work of the Wiseman Lab, investigating dementia in people living with Down syndrome
