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Dr Francesco Gobbo

PhD (He/Him)

Postdoctoral Researcher

Francesco applies his knowledge in advanced imaging and molecular technologies to advance our understanding of the brain in cognition and neurodegeneration.

Techniques

Advanced microscopy & imaging, Mouse behaviour, Mouse in vivo imaging, Viral-mediated expression, Optogenetics

Biography

Francesco was born in Italy near Padua in 1989. In 2008, he was admitted to prestigious Scuola Normale Superiore for Natural Sciences, where he graduated in 2013. He obtained a BSc and MSc in Molecular and Cellular Biology from the University of Pisa in 2011 and 2013. In 2018 he obtained a PhD in Neurobiology from Scuola Normale Superiore.

Research interest

After joining the University of Edinburgh, I have worked with Prof. Richard Morris for 5 years and later joined the lab or Prof. Tara Spires-Jones. My interests include memory and related molecular modifications at the synaptic level in health and neurodegeneration. During my PhD, I developed potentiation reporters to map potentiated synapses in the brain during behavioural tasks. In Richard Morris's lab, I developed the application of microendoscopic recording of calcium activity in the rat hippocampus to study the stability of memories. and how information is accessed during remembering and planning. In Spires-Jones's lab, I am applying my molecular and imaging expertise to elucidate the correlate of synaptic elimination or survival with their activity status during early neurodegenerative injuries. 

Key publications

Acta Neuropathol
Published

Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.

Authors
Martí Colom-Cadena, Jamie Toombs, Elizabeth Simzer, Kristjan Holt, Robert McGeachan, Jane Tulloch, Rosemary J Jackson, James H Catterson, Maxwell P Spires-Jones, Jamie Rose, Lora Waybright, Anthony O Caggiano, Declan King, Francesco Gobbo, Caitlin Davies, Monique Hooley, Sophie Dunnett, Robert Tempelaar, Soraya Meftah, Makis Tzioras, Mary E Hamby, Nicholas J Izzo, Susan M Catalano, Claire S Durrant, Colin Smith, Owen Dando, Tara L Spires-Jones
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.