On 27 June, an international forum of scientists came together at King’s College London to examine the core biology of the synapse and explore possible reasons for its demise in pathological conditions. We take a look at what was discussed, and some key messages taken from the day.
Fundamental to communication in the nervous system, synapses are not only mere junctions between neurons, but dynamic and sophisticated arrangements, coding information passed across the brain and beyond. Dysfunction, and ultimate disintegration of synapses, is a core characteristic of neurodegenerative disease and much research is focussed on finding ways to protect these precious structures.
Organised by UK DRI Group Leader Kei Cho, and in conjunction with King’s College London, the summer synapse symposium -'Physiology and Pathophysiology' - aimed to provoke stimulating discussion on this fundamental topic area in dementia research, by assembling a diverse range of international speakers from both within the UK DRI and further afield.