Labs

Our research teams

The labs at the UK DRI are where discovery happens. Led by our Group Leaders and Emerging Leaders, they are dynamic hubs of innovation, bringing together researchers at all career stages to investigate the fundamental mechanisms of dementia. Each lab contributes unique expertise and approaches to our collective mission, creating a vibrant ecosystem of scientific inquiry that spans molecular biology, genetics, immune biology, and beyond.

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Autophagosome microscopy image - David Rubinsztein

Rubinsztein Lab

Deciphering the link between neurodegeneration and autophagy

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Cytoplasmic mutant TAF15 engulfs U12 snRNAs in the cytoplasm of HeLa cells

Ruepp Lab

Exploring RNA metabolism in health and neurodegeneration

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Lewy bodies in neuron

Ryten Lab

Leveraging brain transcriptomics to understand the pathophysiology of Lewy body diseases

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A woman looks at her smart watch

Sandor Lab

Developing new ways to detect and monitor Parkinson’s

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Schiavo Lab

Restoring axonal transport deficits as a therapeutic strategy for neurodegenerative diseases

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Researcher putting on EEG cap

Scott Lab

Improving care for patients with neurological conditions by studying the brain's electrical activity

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A sphere of red and blue made stem cell organoid

Selvaraj Lab

Using disruptive technologies to decipher the underlying mechanisms that lead to neuron degeneration in ALS

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A sphere of neurons

Serio Lab

Combining bioengineering, imaging, and stem cell modelling to better understand motor neuron disease and dementia

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Sharp Lab

Using radical new approaches to assess the effects of dementia and improve the lives of people living with the condition

Learn more Sharp Lab