Labs

Our research teams

The labs at the UK DRI are where discovery happens. Led by our Group Leaders and Emerging Leaders, they are dynamic hubs of innovation, bringing together researchers at all career stages to investigate the fundamental mechanisms of dementia. Each lab contributes unique expertise and approaches to our collective mission, creating a vibrant ecosystem of scientific inquiry that spans molecular biology, genetics, immune biology, and beyond.

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Krupic Lab

Understanding early changes in neuron-glia circuits in Alzheimer’s disease

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Lally Lab

Quantifying microstructural injury in the substantia nigra of people living with Parkinson’s disease

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Mallach Lab

Understanding microglial interactions in Parkinson’s and how changes in cellular interactions drive cell death

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A brain with PSP dementia imaged with PET-TSPO

Malpetti Lab

Using specialist brain scans and novel blood tests to measure inflammation and accelerate the development of new treatments

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Marzi Lab

Investigating how epigenetics regulates biological mechanisms in health and disease

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Image showing neuron degeneration in Huntington's disease

Massey Lab

Using recent genetic discoveries to develop new drug targets for Huntington's disease

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Matthews Lab

Exploring neuronal vulnerability and genetic risk variants in Alzheimer’s progression

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McColl Lab

Investigating the role of microglia in neurodegenerative disease

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McEwan Lab

Deciphering the mechanisms of tau accumulation and exploring new methods for treatment of tauopathies

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