Labs

Our research teams

The labs at the UK DRI are where discovery happens. Led by our Group Leaders and Emerging Leaders, they are dynamic hubs of innovation, bringing together researchers at all career stages to investigate the fundamental mechanisms of dementia. Each lab contributes unique expertise and approaches to our collective mission, creating a vibrant ecosystem of scientific inquiry that spans molecular biology, genetics, immune biology, and beyond.

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Mixed species co-culture

Hardingham Lab

Studying astrocytes to better understand their role in helping maintain a healthy brain

Learn more Hardingham Lab

Hardy Lab

Harnessing genetics to build a better understanding of dementia

Learn more Hardy Lab
Astrocytes on the brain surface

Hasel Lab

Deciphering the role of astrocytes at brain borders in neurodegeneration

Learn more Hasel Lab
Three-dimensional reconstruction of perivascular macrophages

Hong Lab

Dissecting pathways by which microglia contribute to region-specific synapse dysfunction in neurodegeneration

Learn more Hong Lab
Small blood vessels in mice

Hunt Lab

Investigating how innate immune activation causes damage to the microvasculature of the brain

Learn more Hunt Lab
iPSC cells

Isaacs Lab

Deciphering the fundamental molecular causes of frontotemporal dementia and ALS

Learn more Isaacs Lab

Jackson Lab

Investigating synaptic vulnerability in Alzheimer's

Learn more Jackson Lab
Woman sleeping in bed

Jaramillo Lab

Using multimodal approaches to evaluate interventions to improve REM sleep in ageing and dementia

Learn more Jaramillo Lab
Co-culture

Klenerman Lab

Determining how protein clumps form, damage the brain and change as the different neurodegenerative diseases develop to know which ones to target for therapies

Learn more Klenerman Lab